Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2003 1
2005 1
2007 1
2008 2
2011 1
2012 2
2013 1
2014 2
2015 2
2016 3
2017 4
2018 2
2019 2
2020 7
2021 8
2022 6
2023 10
2024 6
2025 7
2026 3

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

64 results

Results by year

Filters applied: . Clear all
Page 1
OSBPL3 modulates the immunosuppressive microenvironment and predicts therapeutic outcomes in pancreatic cancer.
Sun Q, Zhu X, Zou Q, Chen Y, Wen T, Jiang T, Li X, Wei F, Xie K, Liu J. Sun Q, et al. Biol Direct. 2025 Jan 9;20(1):5. doi: 10.1186/s13062-025-00596-0. Biol Direct. 2025. PMID: 39789613 Free PMC article.
Transcriptomic sequencing following OSBPL3 knockdown revealed enrichment of immune-related pathways, suggesting OSBPL3's influence on the immune microenvironment. ...Additionally, OSBPL3 expression was linked to resistance to immunotherapy, with high OSBPL …
Transcriptomic sequencing following OSBPL3 knockdown revealed enrichment of immune-related pathways, suggesting OSBPL3's influ …
The relationships of OSBPL3 expression with KI-67 expression and KRAS mutations in CRC: implications for diagnosis and prognosis.
Zhang M, Meng L, Zhang Z, Wu J, Chen X, Wang Y, He J. Zhang M, et al. BMC Med Genomics. 2022 Dec 14;15(1):259. doi: 10.1186/s12920-022-01402-w. BMC Med Genomics. 2022. PMID: 36517805 Free PMC article.
In addition, OSBPL3 and Ki-67 expression was significantly correlated. CONCLUSIONS: OSBPL3 is highly expressed in CRC samples and predicts a worse prognosis. OSBPL3 may become a new potential therapeutic target for CRC....
In addition, OSBPL3 and Ki-67 expression was significantly correlated. CONCLUSIONS: OSBPL3 is highly expressed in CRC samples …
Upregulation of OSBPL3 by HIF1A promotes colorectal cancer progression through activation of RAS signaling pathway.
Jiao HL, Weng BS, Yan SS, Lin ZM, Wang SY, Chen XP, Liang GH, Li XQ, Zhao WY, Huang JY, Zhang D, Zhang LJ, Han FY, Li SN, Chen LJ, Zhu JH, He WF, Ding YQ, Ye YP. Jiao HL, et al. Cell Death Dis. 2020 Jul 24;11(7):571. doi: 10.1038/s41419-020-02793-3. Cell Death Dis. 2020. Retraction in: Cell Death Dis. 2022 Nov 2;13(11):920. doi: 10.1038/s41419-022-05367-7. PMID: 32709922 Free PMC article. Retracted.
Oxysterol-binding protein like protein 3 (OSBPL3) has been shown involving in the development of several human cancers. However, the relationship between OSBPL3 and colorectal cancer (CRC), particularly the role of OSBPL3 in the proliferation, invasion and me …
Oxysterol-binding protein like protein 3 (OSBPL3) has been shown involving in the development of several human cancers. However, the …
OSBPL3 drives colorectal cancer progression via Hippo-YAP signaling and modulates MEK inhibitor sensitivity.
Zhong Y, Zheng C, Wang Z, Zhang W, Wu H, Luo J, Zhang H, Wang C, Zhang C, Hu H, Yuan Z, Wang M, Zhang Q, Wang G. Zhong Y, et al. Commun Biol. 2026 Mar 7. doi: 10.1038/s42003-026-09811-8. Online ahead of print. Commun Biol. 2026. PMID: 41794997 Free article.
Here we demonstrate that oxysterol-binding protein-like 3 (OSBPL3) modulates Hippo-YAP signaling to drive tumor aggressiveness. Analysis of clinical specimens and experimental models shows that elevated OSBPL3 levels in colorectal cancer tissues correlate with short …
Here we demonstrate that oxysterol-binding protein-like 3 (OSBPL3) modulates Hippo-YAP signaling to drive tumor aggressiveness. Analy …
Glucocorticoids, genes and brain function.
Juszczak GR, Stankiewicz AM. Juszczak GR, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Mar 2;82:136-168. doi: 10.1016/j.pnpbp.2017.11.020. Epub 2017 Nov 24. Prog Neuropsychopharmacol Biol Psychiatry. 2018. PMID: 29180230 Review.
Other genes are involved in the regulation of metabolism (Gpd1, Aldoc and Pdk4), actin cytoskeleton (Myh2, Nedd9, Mical2, Rhou, Arl4d, Osbpl3, Arhgef3, Sdc4, Rdx, Wipf3, Chst1 and Hepacam), autophagy (Eva1a and Plekhf1), vesicular transport (Rhob, Ehd3, Vps37b and Scamp2), …
Other genes are involved in the regulation of metabolism (Gpd1, Aldoc and Pdk4), actin cytoskeleton (Myh2, Nedd9, Mical2, Rhou, Arl4d, Os …
OSBPL3 promotes LUAD metastasis and glycolysis through transcriptional upregulation of PLAU via NFE2L2.
Zhang Q, Zhang J, Li J, Chen S, Liu Y, Li K, Guo M. Zhang Q, et al. Transl Oncol. 2026 Feb 12;66:102693. doi: 10.1016/j.tranon.2026.102693. Online ahead of print. Transl Oncol. 2026. PMID: 41687403 Free PMC article.
In this study, we elucidate the oncogenic functions and underlying mechanisms of OSBPL3 in LUAD pathogenesis. Analysis of clinical specimens revealed upregulated OSBPL3 expression in LUAD, which correlated with unfavorable patient outcomes. ...Both genetic inhibitio …
In this study, we elucidate the oncogenic functions and underlying mechanisms of OSBPL3 in LUAD pathogenesis. Analysis of clinical sp …
Prognostic and biological function value of OSBPL3 in colorectal cancer analyzed by multi-omic data analysis.
Wang C, He Y, He Y, Liang W, Zhou C, Wu M, Meng Z, Li W, Cao J. Wang C, et al. BMC Gastroenterol. 2023 Aug 7;23(1):270. doi: 10.1186/s12876-023-02824-1. BMC Gastroenterol. 2023. PMID: 37550605 Free PMC article.
Correlations between immune cells and OSBPL3 was analyzed. Drug sensitivity between the two OSBPL3 expression groups was compared. ...T cell gamma delta and T cell follicular helper were significantly different in the high and low OSBPL3 expression groups. Mo …
Correlations between immune cells and OSBPL3 was analyzed. Drug sensitivity between the two OSBPL3 expression groups was compa …
Integrated bioinformatics analysis reveals the function and prognostic value of OSBPL3 in hepatocellular carcinoma.
Su Y, Xue C, Gu X, Sun Y, Zhang R, Li L. Su Y, et al. Heliyon. 2023 Jun 12;9(6):e17223. doi: 10.1016/j.heliyon.2023.e17223. eCollection 2023 Jun. Heliyon. 2023. PMID: 37389070 Free PMC article.
Recent studies have shown that oxysterol-binding protein-like 3 (OSBPL3) plays a crucial role in human cancers. Nevertheless, the specific functional roles and potential clinical values of OSBPL3 in LIHC are not completely known. METHODS: Multiple web portals and pu …
Recent studies have shown that oxysterol-binding protein-like 3 (OSBPL3) plays a crucial role in human cancers. Nevertheless, the spe …
Oxysterol binding protein-like 3 (OSBPL3) is a novel driver gene that promotes tumor growth in part through R-Ras/Akt signaling in gastric cancer.
Hu Q, Masuda T, Koike K, Sato K, Tobo T, Kuramitsu S, Kitagawa A, Fujii A, Noda M, Tsuruda Y, Otsu H, Kuroda Y, Ito S, Oki E, Mimori K. Hu Q, et al. Sci Rep. 2021 Sep 28;11(1):19178. doi: 10.1038/s41598-021-98485-9. Sci Rep. 2021. PMID: 34584127 Free PMC article.
The biological functions and mechanisms of OSBPL3 in GC were examined in vitro and in vivo using GC cells. The association between OSBPL3 expression and clinical outcome in GC patients was also evaluated. Overexpression of OSBPL3 was detected in GC cells with …
The biological functions and mechanisms of OSBPL3 in GC were examined in vitro and in vivo using GC cells. The association between …
64 results