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Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function.
Meisgen S, Hedlund M, Ambrosi A, Folkersen L, Ottosson V, Forsberg D, Thorlacius GE, Biavati L, Strandberg L, Mofors J, Ramskold D, Ruhrmann S, Meneghel L, Nyberg W, Espinosa A, Hamilton RM, Franco-Cereceda A, Hamsten A, Olsson T, Greene L, Eriksson P, Gemzell-Danielsson K, Salomonsson S, Kuchroo VK, Herlenius E, Kockum I, Sonesson SE, Wahren-Herlenius M. Meisgen S, et al. Among authors: ottosson v. Ann Rheum Dis. 2022 Aug;81(8):1151-1161. doi: 10.1136/annrheumdis-2021-221714. Epub 2022 Apr 25. Ann Rheum Dis. 2022. PMID: 35470161 Free PMC article.
Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero.
Hedlund M, Thorlacius GE, Ivanchenko M, Ottosson V, Kyriakidis N, Lagnefeldt L, Tingström J, Sirsjö A, Bengtsson AA, Aronsson E, Gemzell-Danielsson K, Ronnblom L, Bergman G, Espinosa A, Sonesson SE, Eloranta ML, Wahren-Herlenius M. Hedlund M, et al. Among authors: ottosson v. RMD Open. 2020 Jan;6(1):e000989. doi: 10.1136/rmdopen-2019-000989. RMD Open. 2020. PMID: 31958275 Free PMC article.
Natural killer cells and type II interferon in Ro/SSA and La/SSB autoantibody-exposed newborns at risk of congenital heart block.
Ivanchenko M, Thorlacius GE, Hedlund M, Ottosson V, Meneghel L, Björkander S, Ossoinak A, Tingström J, Bremme K, Sverremark-Ekström E, Gemzell-Danielsson K, Sonesson SE, Chemin K, Wahren-Herlenius M. Ivanchenko M, et al. Among authors: ottosson v. Ann Rheum Dis. 2021 Feb;80(2):194-202. doi: 10.1136/annrheumdis-2019-216786. Epub 2020 Oct 1. Ann Rheum Dis. 2021. PMID: 33004330