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Did you mean p niklas (386 results)?
Genome-wide cell-free DNA fragmentation in patients with cancer.
Cristiano S, Leal A, Phallen J, Fiksel J, Adleff V, Bruhm DC, Jensen SØ, Medina JE, Hruban C, White JR, Palsgrove DN, Niknafs N, Anagnostou V, Forde P, Naidoo J, Marrone K, Brahmer J, Woodward BD, Husain H, van Rooijen KL, Ørntoft MW, Madsen AH, van de Velde CJH, Verheij M, Cats A, Punt CJA, Vink GR, van Grieken NCT, Koopman M, Fijneman RJA, Johansen JS, Nielsen HJ, Meijer GA, Andersen CL, Scharpf RB, Velculescu VE. Cristiano S, et al. Nature. 2019 Jun;570(7761):385-389. doi: 10.1038/s41586-019-1272-6. Epub 2019 May 29. Nature. 2019. PMID: 31142840 Free PMC article.
Genome-wide repeat landscapes in cancer and cell-free DNA.
Annapragada AV, Niknafs N, White JR, Bruhm DC, Cherry C, Medina JE, Adleff V, Hruban C, Mathios D, Foda ZH, Phallen J, Scharpf RB, Velculescu VE. Annapragada AV, et al. Sci Transl Med. 2024 Mar 13;16(738):eadj9283. doi: 10.1126/scitranslmed.adj9283. Epub 2024 Mar 13. Sci Transl Med. 2024. PMID: 38478628 Free PMC article.
Detection and characterization of lung cancer using cell-free DNA fragmentomes.
Mathios D, Johansen JS, Cristiano S, Medina JE, Phallen J, Larsen KR, Bruhm DC, Niknafs N, Ferreira L, Adleff V, Chiao JY, Leal A, Noe M, White JR, Arun AS, Hruban C, Annapragada AV, Jensen SØ, Ørntoft MW, Madsen AH, Carvalho B, de Wit M, Carey J, Dracopoli NC, Maddala T, Fang KC, Hartman AR, Forde PM, Anagnostou V, Brahmer JR, Fijneman RJA, Nielsen HJ, Meijer GA, Andersen CL, Mellemgaard A, Bojesen SE, Scharpf RB, Velculescu VE. Mathios D, et al. Nat Commun. 2021 Aug 20;12(1):5060. doi: 10.1038/s41467-021-24994-w. Nat Commun. 2021. PMID: 34417454 Free PMC article.
ctDNA response after pembrolizumab in non-small cell lung cancer: phase 2 adaptive trial results.
Anagnostou V, Ho C, Nicholas G, Juergens RA, Sacher A, Fung AS, Wheatley-Price P, Laurie SA, Levy B, Brahmer JR, Balan A, Niknafs N, Avrutin E, Zhu L, Sausen M, Bradbury PA, O'Donnell-Tormey J, Gaudreau PO, Ding K, Dancey J. Anagnostou V, et al. Nat Med. 2023 Oct;29(10):2559-2569. doi: 10.1038/s41591-023-02598-9. Epub 2023 Oct 9. Nat Med. 2023. PMID: 37814061 Free PMC article. Clinical Trial.
Detecting Liver Cancer Using Cell-Free DNA Fragmentomes.
Foda ZH, Annapragada AV, Boyapati K, Bruhm DC, Vulpescu NA, Medina JE, Mathios D, Cristiano S, Niknafs N, Luu HT, Goggins MG, Anders RA, Sun J, Meta SH, Thomas DL, Kirk GD, Adleff V, Phallen J, Scharpf RB, Kim AK, Velculescu VE. Foda ZH, et al. Cancer Discov. 2023 Mar 1;13(3):616-631. doi: 10.1158/2159-8290.CD-22-0659. Cancer Discov. 2023. PMID: 36399356 Free PMC article.
We have developed an approach for examining genome-wide cfDNA fragmentation features to provide a high-performing and cost-effective approach for liver cancer detection. See related commentary Rolfo and Russo, p. 532. This article is highlighted in the In This Issue featur …
We have developed an approach for examining genome-wide cfDNA fragmentation features to provide a high-performing and cost-effective approac …
Pathologic features of response to neoadjuvant anti-PD-1 in resected non-small-cell lung carcinoma: a proposal for quantitative immune-related pathologic response criteria (irPRC).
Cottrell TR, Thompson ED, Forde PM, Stein JE, Duffield AS, Anagnostou V, Rekhtman N, Anders RA, Cuda JD, Illei PB, Gabrielson E, Askin FB, Niknafs N, Smith KN, Velez MJ, Sauter JL, Isbell JM, Jones DR, Battafarano RJ, Yang SC, Danilova L, Wolchok JD, Topalian SL, Velculescu VE, Pardoll DM, Brahmer JR, Hellmann MD, Chaft JE, Cimino-Mathews A, Taube JM. Cottrell TR, et al. Ann Oncol. 2018 Aug 1;29(8):1853-1860. doi: 10.1093/annonc/mdy218. Ann Oncol. 2018. PMID: 29982279 Free PMC article. Clinical Trial.
The regression bed is characterized by (i) immune activation-dense tumor infiltrating lymphocytes with macrophages and tertiary lymphoid structures; (ii) massive tumor cell death-cholesterol clefts; and (iii) tissue repair-neovascularization and proliferative fibrosis (each featu …
The regression bed is characterized by (i) immune activation-dense tumor infiltrating lymphocytes with macrophages and tertiary lymphoid str …
Genomic Landscapes of Endometrioid and Mucinous Ovarian Cancers and Morphologically Similar Tumor Types.
Hallberg D, Eastman AC, Koul S, Bruhm DC, Papp E, Davenport S, Adleff V, Ferreira L, Niknafs N, Medina JE, Cristiano S, Hruban C, Fiksel J, Lebarbenchon KP, Aparicio L, Vulpescu NA, Kuo KT, Ahuja N, Drapkin R, Jung E, Kim SH, Eckert MA, Lengyel E, Nakayama K, Ayhan A, Shih IM, Wang TL, Lavie O, Rennert G, Easwaran H, Baylin SB, Press MF, Velculescu VE, Scharpf RB. Hallberg D, et al. Cancer Res Commun. 2025 Nov 1;5(11):1952-1966. doi: 10.1158/2767-9764.CRC-25-0147. Cancer Res Commun. 2025. PMID: 40981433 Free PMC article.
Dynamics of Sequence and Structural Cell-Free DNA Landscapes in Small-Cell Lung Cancer.
Sivapalan L, Iams WT, Belcaid Z, Scott SC, Niknafs N, Balan A, White JR, Kopparapu P, Cann C, Landon BV, Pereira G, Velculescu VE, Hann CL, Lovly CM, Anagnostou V. Sivapalan L, et al. Clin Cancer Res. 2023 Jun 13;29(12):2310-2323. doi: 10.1158/1078-0432.CCR-22-2242. Clin Cancer Res. 2023. PMID: 37071497 Free PMC article.

Patients with sustained molecular responses had longer overall (log-rank P = 0.0006) and progression-free (log-rank P < 0.0001) survival, with molecular responses detected on average 4 weeks earlier than imaging. ...See related commentary by Pellini and Chaudhuri

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Patients with sustained molecular responses had longer overall (log-rank P = 0.0006) and progression-free (log-rank P < 0.0

…
Cell-free DNA fragmentomes for noninvasive detection of liver cirrhosis and other diseases.
Annapragada AV, Foda ZH, Orjuela H, Norton C, Koul S, Niknafs N, Short S, Boyapati K, Bartolomucci A, Mathios D, Noë M, Cherry C, Carey J, Leal A, Chesnick B, Dracopoli NC, Medina JE, Vulpescu NA, Bruhm DC, Bacus S, Adleff V, Kim AK, Baylin SB, Kirk GD, Sorop A, Iacob R, Iacob S, Gheorghe L, Dima S, Ramírez-Zea M, McGlynn KA, Feltoft CL, Johansen JS, Groopman J, Phallen J, Scharpf RB, Velculescu VE. Annapragada AV, et al. Sci Transl Med. 2026 Mar 4;18(839):eadw2603. doi: 10.1126/scitranslmed.adw2603. Epub 2026 Mar 4. Sci Transl Med. 2026. PMID: 41779869 Free PMC article.
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