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Page 1
Vibrational perturbations in the spectra of N-substituted polycyclic aromatic heterocycles revealed by rotational analysis.
Chawananon S, Pirali O, Goubet M, Asselin P. Chawananon S, et al. Phys Chem Chem Phys. 2025 Mar 12;27(11):5531-5542. doi: 10.1039/d4cp04769a. Phys Chem Chem Phys. 2025. PMID: 40007478
In the continuity of a recent high resolution rovibrational study of two-ring centrosymmetric PAHs [S. Chawananon, O. Pirali, M. Goubet and P. Asselin, J. Chem. Phys., 2022, 157, 064301], the present work targets four PAHs with one or two N atoms substituted on one …
In the continuity of a recent high resolution rovibrational study of two-ring centrosymmetric PAHs [S. Chawananon, O. Pirali, M. Goub …
CIC-39Na reverses the thrombocytopenia that characterizes tubular aggregate myopathy.
Cordero-Sanchez C, Pessolano E, Riva B, Vismara M, Trivigno SMG, Clemente N, Aprile S, Ruffinatti FA, Portararo P, Filigheddu N, Zaggia I, Bhela IP, Serafini M, Pirali T, Colombo MP, Torti M, Sangaletti S, Bertoni A, Genazzani AA. Cordero-Sanchez C, et al. Blood Adv. 2022 Aug 9;6(15):4471-4484. doi: 10.1182/bloodadvances.2021006378. Blood Adv. 2022. PMID: 35696753 Free PMC article.
Our group has previously demonstrated that a mouse model bearing the STIM1 p.I115F mutation recapitulates the main features of the STIM1 gain-of-function disorders: muscle weakness and thrombocytopenia. ...Subtle differences in thrombopoiesis were observed in STIM1 p
Our group has previously demonstrated that a mouse model bearing the STIM1 p.I115F mutation recapitulates the main features of the ST …
Artesunate, as a HSP70 ATPase activity inhibitor, induces apoptosis in breast cancer cells.
Pirali M, Taheri M, Zarei S, Majidi M, Ghafouri H. Pirali M, et al. Int J Biol Macromol. 2020 Dec 1;164:3369-3375. doi: 10.1016/j.ijbiomac.2020.08.198. Epub 2020 Aug 27. Int J Biol Macromol. 2020. PMID: 32861782
Our results demonstrated that the artesunate not only induced apoptosis but also lead to the inhibition of HSP70 ATPase activity the in vitro (P < 0.001). The extent of HSP70 refolding inhibition increased with increasing muM concentrations of artesunate. ...
Our results demonstrated that the artesunate not only induced apoptosis but also lead to the inhibition of HSP70 ATPase activity the in vitr …
A multicomponent approach in the discovery of indoleamine 2,3-dioxygenase 1 inhibitors: Synthesis, biological investigation and docking studies.
Griglio A, Torre E, Serafini M, Bianchi A, Schmid R, Coda Zabetta G, Massarotti A, Sorba G, Pirali T, Fallarini S. Griglio A, et al. Bioorg Med Chem Lett. 2018 Feb 15;28(4):651-657. doi: 10.1016/j.bmcl.2018.01.032. Epub 2018 Feb 2. Bioorg Med Chem Lett. 2018. PMID: 29398544
In this study, the Passerini and Ugi multicomponent reactions have been employed to assemble a small library of imidazothiazoles that target IDO1. While the p-bromophenyl and the imidazothiazole moieties have been kept fixed, a full SAR study has been performed on the side …
In this study, the Passerini and Ugi multicomponent reactions have been employed to assemble a small library of imidazothiazoles that target …
Acaricidal effect of Pelargonium roseum and Eucalyptus globulus essential oils against adult stage of Rhipicephalus (Boophilus) annulatus in vitro.
Pirali-Kheirabadi K, Razzaghi-Abyaneh M, Halajian A. Pirali-Kheirabadi K, et al. Vet Parasitol. 2009 Jun 10;162(3-4):346-9. doi: 10.1016/j.vetpar.2009.03.015. Epub 2009 Mar 17. Vet Parasitol. 2009. PMID: 19356854
The mass of produced eggs in adult female ticks exposed to both P. roseum and E. globulus EOs had decreased dose-dependently. It was significant for only 2.5% and 5.0% dilutions of P. roseum EO, comparing the non-treated control (P<0.05). The highest decre …
The mass of produced eggs in adult female ticks exposed to both P. roseum and E. globulus EOs had decreased dose-dependently. It was …
Gout, allopurinol intake and clinical outcomes in the hospitalized multimorbid elderly.
Franchi C, Salerno F, Conca A, Djade CD, Tettamanti M, Pasina L, Corrao S, Marengoni A, Marcucci M, Mannucci PM, Nobili A; REPOSI Investigators. Franchi C, et al. Eur J Intern Med. 2014 Nov;25(9):847-52. doi: 10.1016/j.ejim.2014.09.019. Epub 2014 Oct 22. Eur J Intern Med. 2014. PMID: 25439099
They had more co-morbidities (7.0 vs 5.6; P<0.0001) and consumed more drugs (6.8 vs 5.0; P<0.0001). The CIRS (co-morbidity index) was worse in these patients (OR 1.28 95% CI 1.15-1.41). ...
They had more co-morbidities (7.0 vs 5.6; P<0.0001) and consumed more drugs (6.8 vs 5.0; P<0.0001). The CIRS (co-morbidi …
The basal to total insulin ratio in outpatients with diabetes on basal-bolus regimen.
Castellano E, Attanasio R, Giagulli VA, Boriano A, Terzolo M, Papini E, Guastamacchia E, Monti S, Aglialoro A, Agrimi D, Ansaldi E, Babini AC, Blatto A, Brancato D, Casile C, Cassibba S, Crescenti C, De Feo ML, Del Prete A, Disoteo O, Ermetici F, Fiore V, Fusco A, Gioia D, Grassi A, Gullo D, Lo Pomo F, Miceli A, Nizzoli M, Pellegrino M, Pirali B, Santini C, Settembrini S, Tortato E, Triggiani V, Vacirca A, Borretta G; all on behalf of Associazione Medici Endocrinologi (AME). Castellano E, et al. J Diabetes Metab Disord. 2018 Oct 1;17(2):393-399. doi: 10.1007/s40200-018-0358-2. eCollection 2018 Dec. J Diabetes Metab Disord. 2018. PMID: 30918874 Free PMC article.
The b/T ratio was lower than 0.50 in both groups: 0.46 0.14 in DM1 and 0.43 0.15 in DM2 patients (p = 0.0011). The b/T was significantly higher in the patients taking metformin in both groups, and significantly different according to the type of basal insulin (Degludec …
The b/T ratio was lower than 0.50 in both groups: 0.46 0.14 in DM1 and 0.43 0.15 in DM2 patients (p = 0.0011). The b/T was signif …
28 results