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58 results

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Page 1
Acute kidney disease beyond day 7 after major surgery: a secondary analysis of the EPIS-AKI trial.
Meersch M, Weiss R, Strauß C, Albert F, Booke H, Forni L, Pittet JF, Kellum JA, Rosner M, Mehta R, Bellomo R, Rosenberger P, Zarbock A; EPIS-AKI Investigators. Meersch M, et al. Intensive Care Med. 2024 Feb;50(2):247-257. doi: 10.1007/s00134-023-07314-2. Epub 2024 Jan 29. Intensive Care Med. 2024. PMID: 38285051 Free PMC article.

Rates of AKD after 7 days significantly increased with the severity (19.1% Kidney Disease Improving Global Outcomes [KDIGO] 1, 24.5% KDIGO2, 34.3% KDIGO3; P < 0.001) and duration (15.5% transient vs 38.3% persistent AKI; P < 0.001) of early postoperative-AKI.

Rates of AKD after 7 days significantly increased with the severity (19.1% Kidney Disease Improving Global Outcomes [KDIGO] 1, 24.5% KDIGO2, …
Evaluation of protective effects of methylene blue on cisplatin-induced nephrotoxicity.
Usefzay O, Yari S, Amiri P, Hasanein P. Usefzay O, et al. Biomed Pharmacother. 2022 Jun;150:113023. doi: 10.1016/j.biopha.2022.113023. Epub 2022 Apr 25. Biomed Pharmacother. 2022. PMID: 35483196 Free article.

The results showed that the MB (4 mg/kg) + CP treated rats underwent a lesser weight loss compared to the CP group (p < 0.05 and p < 0.001, respectively). The kidney weight decreased significantly in the CP + MB group compared to the CP group (p < 0.

The results showed that the MB (4 mg/kg) + CP treated rats underwent a lesser weight loss compared to the CP group (p < 0.05 and

Preventive use of berberine in inhibition of lead-induced renal injury in rats.
Hasanein P, Riahi H. Hasanein P, et al. Environ Sci Pollut Res Int. 2018 Feb;25(5):4896-4903. doi: 10.1007/s11356-017-0702-y. Epub 2017 Dec 4. Environ Sci Pollut Res Int. 2018. PMID: 29204934

Lead caused an increase in malondialdehyde (P < 0.001) and total oxidant status (P < 0.01), and a decrease in reduced glutathione (P < 0.001), catalase (P < 0.01), superoxide dismutase (P < 0.001), and total antioxidant capacity (

Lead caused an increase in malondialdehyde (P < 0.001) and total oxidant status (P < 0.01), and a decrease in reduced gl

Awareness and preparedness of healthcare workers against the first wave of the COVID-19 pandemic: A cross-sectional survey across 57 countries.
Huy NT, Chico RM, Huan VT, Shaikhkhalil HW, Uyen VNT, Qarawi ATA, Alhady STM, Vuong NL, Truong LV, Luu MN, Dumre SP, Imoto A, Lee PN, Tam DNH, Ng SJ, Hashan MR, Matsui M, Duc NTM, Karimzadeh S, Koonrungsesomboon N, Smith C, Cox S, Moji K, Hirayama K, Linh LK, Abbas KS, Dung TNT, Mohammed Ali Al-Ahdal T, Balogun EO, Duy NT, Mohamed Eltaras M, Huynh T, Hue NTL, Khue BD, Gad A, Tawfik GM, Kubota K, Nguyen HM, Pavlenko D, Trang VTT, Vu LT, Hai Yen T, Yen-Xuan NT, Trang LT, Dong V, Sharma A, Dat VQ, Soliman M, Abdul Aziz J, Shah J, Hung PDL, Jee YS, Phuong DTH, Quynh TTH, Giang HTN, Huynh VTN, Thi NA, Dhouibi N, Phan T, Duru V, Nam NH, Ghozy S; contributors of the TMGH-Global COVID-19 Collaborative; TMGH-Global COVID-19 Collaborative. Huy NT, et al. PLoS One. 2021 Dec 22;16(12):e0258348. doi: 10.1371/journal.pone.0258348. eCollection 2021. PLoS One. 2021. PMID: 34936646 Free PMC article.
HCWs at COVID-19 designated facilities with previous outbreak experience, or HCWs who were trained for dealing with the SARS-CoV-2 outbreak, had significantly higher levels of preparedness and awareness (p<0.001). Association rule mining suggests that nurses and doctors …
HCWs at COVID-19 designated facilities with previous outbreak experience, or HCWs who were trained for dealing with the SARS-CoV-2 outbreak, …
Alogliptin after acute coronary syndrome in patients with type 2 diabetes.
White WB, Cannon CP, Heller SR, Nissen SE, Bergenstal RM, Bakris GL, Perez AT, Fleck PR, Mehta CR, Kupfer S, Wilson C, Cushman WC, Zannad F; EXAMINE Investigators. White WB, et al. N Engl J Med. 2013 Oct 3;369(14):1327-35. doi: 10.1056/NEJMoa1305889. Epub 2013 Sep 2. N Engl J Med. 2013. PMID: 23992602 Free article. Clinical Trial.
A primary end-point event occurred in 305 patients assigned to alogliptin (11.3%) and in 316 patients assigned to placebo (11.8%) (hazard ratio, 0.96; upper boundary of the one-sided repeated confidence interval, 1.16; P<0.001 for noninferiority). Glycated hemoglobin le …
A primary end-point event occurred in 305 patients assigned to alogliptin (11.3%) and in 316 patients assigned to placebo (11.8%) (hazard ra …
Beneficial effects of rosmarinic acid against alcohol-induced hepatotoxicity in rats.
Hasanein P, Seifi R. Hasanein P, et al. Can J Physiol Pharmacol. 2018 Jan;96(1):32-37. doi: 10.1139/cjpp-2017-0135. Epub 2017 Jul 4. Can J Physiol Pharmacol. 2018. PMID: 28675794
Ethanol increased hepatic lipid peroxidation (P < 0.001) and decreased hepatic levels of reduced glutathione (P < 0.01), catalase (P < 0.05), and superoxide dismutase (P < 0.001) compared with control group. ...

Ethanol increased hepatic lipid peroxidation (P < 0.001) and decreased hepatic levels of reduced glutathione (P < 0.01),

The interactive effects of verapamil and CB1 cannabinoid receptor antagonist/inverse agonist, AM251 on passive avoidance learning and memory in rat.
Karimi SA, Noorbakhsh M, Komaki H, Reza Nikoo M, Hasanein P, Shahidi S, Faraji N, Komaki A. Karimi SA, et al. Behav Pharmacol. 2022 Apr 1;33(2&3):222-229. doi: 10.1097/FBP.0000000000000638. Behav Pharmacol. 2022. PMID: 34845169
Male Wistar rats were administered verapamil (10, 25 and 50 mg/kg) or saline intraperitoneally (i.p) daily for 13 days (n = 10/group). After this treatment period, a learning test (acquisition) was performed, and a retrieval test was performed the following day. ...Pre-tra …
Male Wistar rats were administered verapamil (10, 25 and 50 mg/kg) or saline intraperitoneally (i.p) daily for 13 days (n = 10/group) …
Anterior or posterior SWL in proximal ureteral stones opposite to 4th and 5th lumbar vertebrae?
Fathelbab TK, Hasanein MGS, Fawzy AM. Fathelbab TK, et al. World J Urol. 2021 Jan;39(1):255-261. doi: 10.1007/s00345-020-03174-3. Epub 2020 Apr 15. World J Urol. 2021. PMID: 32296925 Clinical Trial.
RESULTS: Anterior approach needed less power to reach SFR (p = 0.05) in less number of sessions where 90% of cases in anterior group had only one session to reach SFR versus 52% in posterior group (p = 0.001). ...SFR does not differed significantly between study gro …
RESULTS: Anterior approach needed less power to reach SFR (p = 0.05) in less number of sessions where 90% of cases in anterior group …
58 results