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Eplerenone reduces renal ischaemia/reperfusion injury by modulating Klotho, NF-κB and SIRT1/SIRT3/PGC-1α signalling pathways.
Barati A, Rahbar Saadat Y, Meybodi SM, Nouraei S, Moradi K, Kamrani Moghaddam F, Malekinejad Z, Hosseiniyan Khatibi SM, Zununi Vahed S, Bagheri Y. Barati A, et al. Among authors: kamrani moghaddam f. J Pharm Pharmacol. 2023 Jun 5;75(6):819-827. doi: 10.1093/jpp/rgac054. J Pharm Pharmacol. 2023. PMID: 35866843

KEY FINDINGS: Eplerenone pre-treatment significantly could improve IR-induced pathological changes and kidney function and increase the renal antioxidant factors compared to the IR group (P < 0.05). Furthermore, in the Eplerenone + IR group, significant elevation of the

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KEY FINDINGS: Eplerenone pre-treatment significantly could improve IR-induced pathological changes and kidney function and increase the rena …
The inhibition of epidermal growth factor receptor signaling by hexagonal selenium nanoparticles modified by SiRNA.
Kamrani Moghaddam L, Ramezani Paschepari S, Zaimy MA, Abdalaian A, Jebali A. Kamrani Moghaddam L, et al. Cancer Gene Ther. 2016 Sep;23(9):321-5. doi: 10.1038/cgt.2016.38. Epub 2016 Sep 9. Cancer Gene Ther. 2016. PMID: 27608774
The percentage of apoptotic cells was significantly increased in all cell lines when exposed to HSNM-SiRNA (P>0.05). HSNM-SiRNA in A549 and H1299 cells significantly increased the proportion of cells in G1/G0 phase and significantly decreased the proportion of cells in …
The percentage of apoptotic cells was significantly increased in all cell lines when exposed to HSNM-SiRNA (P>0.05). HSNM-SiRNA in …