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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
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2004 6
2005 3
2006 1
2008 2
2009 5
2010 8
2011 2
2012 10
2013 6
2014 8
2015 4
2016 5
2017 8
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116 results

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Page 1
P2RY13 Exacerbates Intestinal Inflammation by Damaging the Intestinal Mucosal Barrier via Activating IL-6/STAT3 Pathway.
Wu X, Wei S, Chen M, Li J, Wei Y, Zhang J, Dong W. Wu X, et al. Int J Biol Sci. 2022 Aug 1;18(13):5056-5069. doi: 10.7150/ijbs.74304. eCollection 2022. Int J Biol Sci. 2022. PMID: 35982893 Free PMC article.
The pathogenesis of ulcerative colitis (UC) is unclear, while genetic factors have been confirmed to play an important role in its development. P2RY13 is a G protein-coupled receptor (GPCRs), which are involved in the pathogenesis of inflammation and immune disorders. ...I …
The pathogenesis of ulcerative colitis (UC) is unclear, while genetic factors have been confirmed to play an important role in its developme …
P2RY13 is a prognostic biomarker and associated with immune infiltrates in renal clear cell carcinoma: A comprehensive bioinformatic study.
Chu J, Liu W, Hu X, Zhang H, Jiang J. Chu J, et al. Health Sci Rep. 2023 Dec 1;6(12):e1646. doi: 10.1002/hsr2.1646. eCollection 2023 Dec. Health Sci Rep. 2023. PMID: 38045624 Free PMC article.
This study aimed to investigate the role of P2RY13 in the progression of ccRCC and elucidate its mechanism of action. METHODS: Gene Expression Omnibus and The Cancer Genome Atlas databases were used to extract gene expression profiles of ccRCC. ...P2RY13 may play a …
This study aimed to investigate the role of P2RY13 in the progression of ccRCC and elucidate its mechanism of action. METHODS: Gene E …
Identification of P2RY13 as an immune-related prognostic biomarker in lung adenocarcinoma: A public database-based retrospective study.
Lin J, Wu C, Ma D, Hu Q. Lin J, et al. PeerJ. 2021 May 5;9:e11319. doi: 10.7717/peerj.11319. eCollection 2021. PeerJ. 2021. PMID: 33996281 Free PMC article.
Univariate Cox regression and survival analyses revealed that P2Y purinoceptor 13 (P2RY13) was a favorable factor for the prognosis of LUAD. ssGSEA and Spearman correlation analysis demonstrated that P2RY13 was highly correlated with various TIICs and immune functio …
Univariate Cox regression and survival analyses revealed that P2Y purinoceptor 13 (P2RY13) was a favorable factor for the prognosis o …
Neutrophil infiltration associated genes on the prognosis and tumor immune microenvironment of lung adenocarcinoma.
Liu R, Zhu G, Sun Y, Li M, Hu Z, Cao P, Li X, Song Z, Chen J. Liu R, et al. Front Immunol. 2023 Dec 22;14:1304529. doi: 10.3389/fimmu.2023.1304529. eCollection 2023. Front Immunol. 2023. PMID: 38204755 Free PMC article.
We further found that overexpressed TNFAIP6 and TLR6 and downregulated P2RY13, SCARF1, DPEP2, PRAM1, CYP27A1, CFP, GPX3, and NCF1 in LUAD tissue might be potentially associated with neutrophils pro-tumor effects. The following in vitro experiments demonstrated that TNFAIP6 …
We further found that overexpressed TNFAIP6 and TLR6 and downregulated P2RY13, SCARF1, DPEP2, PRAM1, CYP27A1, CFP, GPX3, and NCF1 in …
Transcriptomic analysis reveals shared gene signatures and molecular mechanisms between obesity and periodontitis.
Cai Y, Zuo X, Zuo Y, Wu S, Pang W, Ma K, Yi Q, Tan L, Deng H, Qu X, Chen X. Cai Y, et al. Front Immunol. 2023 Mar 29;14:1101854. doi: 10.3389/fimmu.2023.1101854. eCollection 2023. Front Immunol. 2023. PMID: 37063877 Free PMC article.
Functional analysis showed that these genes were mainly enriched in immune-related pathways such as B cell receptor signalling, leukocyte migration and cellular defence responses. 14 hub genes (FGR, MNDA, NCF2, FYB1, EVI2B, LY86, IGSF6, CTSS, CXCR4, LCK, FCN1, CXCL2, P2RY13 …
Functional analysis showed that these genes were mainly enriched in immune-related pathways such as B cell receptor signalling, leukocyte mi …
Identification of key biomarkers for predicting atherosclerosis progression in polycystic ovary syndrome via bioinformatics analysis and machine learning.
Zhang W, Wu Y, Yuan Y, Wang L, Yu B, Li X, Yao Z, Liang B. Zhang W, et al. Comput Biol Med. 2024 Dec;183:109239. doi: 10.1016/j.compbiomed.2024.109239. Epub 2024 Oct 12. Comput Biol Med. 2024. PMID: 39396400
Furthermore, we identified two hub genes (MMP9 and P2RY13) by three machine learning algorithms. The nomogram model based on MMP9 and P2RY13 can be used as a new diagnostic model to differentiate AS in PCOS women (AUC>0.9). ...Single gene GSEA analysis suggested …
Furthermore, we identified two hub genes (MMP9 and P2RY13) by three machine learning algorithms. The nomogram model based on MMP9 and …
Single cell RNA sequencing confirms retinal microglia activation associated with early onset retinal degeneration.
Kumari A, Ayala-Ramirez R, Zenteno JC, Huffman K, Sasik R, Ayyagari R, Borooah S. Kumari A, et al. Sci Rep. 2022 Sep 10;12(1):15273. doi: 10.1038/s41598-022-19351-w. Sci Rep. 2022. PMID: 36088481 Free PMC article.
Single cell RNA sequencing of Mfrp(KI/KI) mice retinal microglia showed a significantly higher number of pan-macrophage marker Iba-1 and F4/80 positive cells with increased expression of activation marker (CD68) and lowered microglial homeostatic markers (TMEM119, P2ry13, …
Single cell RNA sequencing of Mfrp(KI/KI) mice retinal microglia showed a significantly higher number of pan-macrophage marker Iba-1 and F4/ …
Plasma cell signatures predict prognosis and treatment efficacy for lung adenocarcinoma.
Shu L, Tang J, Liu S, Tao Y. Shu L, et al. Cell Oncol (Dordr). 2024 Apr;47(2):555-571. doi: 10.1007/s13402-023-00883-w. Epub 2023 Oct 9. Cell Oncol (Dordr). 2024. PMID: 37814076
RESULTS: We constructed PC scores based on seventeen PC-related hub genes (ELOVL6, MFI2, FURIN, DOK1, ERO1LB, CLEC7A, ZNF431, KIAA1324, NUCB2, TXNDC11, ICAM3, CR2, CLIC6, CARNS1, P2RY13, KLF15, and SLC24A4). Higher age, TNM stage, and PC scores independently predicted shor …
RESULTS: We constructed PC scores based on seventeen PC-related hub genes (ELOVL6, MFI2, FURIN, DOK1, ERO1LB, CLEC7A, ZNF431, KIAA1324, NUCB …
Novel candidate blood-based transcriptional biomarkers of Machado-Joseph disease.
Raposo M, Bettencourt C, Maciel P, Gao F, Ramos A, Kazachkova N, Vasconcelos J, Kay T, Rodrigues AJ, Bettencourt B, Bruges-Armas J, Geschwind D, Coppola G, Lima M. Raposo M, et al. Mov Disord. 2015 Jun;30(7):968-75. doi: 10.1002/mds.26238. Epub 2015 Apr 25. Mov Disord. 2015. PMID: 25914309
Fourteen of these were further tested in an independent set of 42 patients and 35 controls; 10 genes maintained the up-regulation trend (FCGR3B, CSR2RA, CLC, TNFSF14, SLA, P2RY13, FPR2, SELPLG, YIPF6, and GPR96); FCGR3B, P2RY13, and SELPLG were significantly up-regu …
Fourteen of these were further tested in an independent set of 42 patients and 35 controls; 10 genes maintained the up-regulation trend (FCG …
Integrated bioinformatics approaches to investigate alterations in transcriptomic profiles of monkeypox infected human cell line model.
Anuraga G, Lang J, Xuan DTM, Ta HDK, Jiang JZ, Sun Z, Dey S, Kumar S, Singh A, Kajla G, Wang WJ, Wang CY. Anuraga G, et al. J Infect Public Health. 2024 Jan;17(1):60-69. doi: 10.1016/j.jiph.2023.10.035. Epub 2023 Nov 2. J Infect Public Health. 2024. PMID: 37992435 Free article.
This association was identified based on the regulation of genes such as C1orf21, C19orf48, HRK, IL8, GULP1, SCAND2, ATP5C1, FEZ1, SGSH, TACC2, CYP4X1, MMP1, CPB1, P2RY13, WDR27, PRPF4, and ENDOD1. CONCLUSIONS: This study can improve our understanding of the mechanisms und …
This association was identified based on the regulation of genes such as C1orf21, C19orf48, HRK, IL8, GULP1, SCAND2, ATP5C1, FEZ1, SGSH, TAC …
116 results