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Substituted imidazole of 5-fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine Inactivates cytochrome P450 2D6 by protein adduction.
Nagy LD, Mocny CS, Diffenderfer LE, Hsi DJ, Butler BF, Arthur EJ, Fletke KJ, Palamanda JR, Nomeir AA, Furge LL. Nagy LD, et al. Among authors: palamanda jr. Drug Metab Dispos. 2011 Jun;39(6):974-83. doi: 10.1124/dmd.110.037630. Epub 2011 Mar 21. Drug Metab Dispos. 2011. PMID: 21422192 Free PMC article.
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