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2021 5
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Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Leppek K, Byeon GW, Kladwang W, Wayment-Steele HK, Kerr CH, Xu AF, Kim DS, Topkar VV, Choe C, Rothschild D, Tiu GC, Wellington-Oguri R, Fujii K, Sharma E, Watkins AM, Nicol JJ, Romano J, Tunguz B, Diaz F, Cai H, Guo P, Wu J, Meng F, Shi S, Participants E, Dormitzer PR, Solórzano A, Barna M, Das R. Leppek K, et al. Among authors: participants e. Nat Commun. 2022 Mar 22;13(1):1536. doi: 10.1038/s41467-022-28776-w. Nat Commun. 2022. PMID: 35318324 Free PMC article.
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Wayment-Steele HK, Kim DS, Choe CA, Nicol JJ, Wellington-Oguri R, Watkins AM, Parra Sperberg RA, Huang PS, Participants E, Das R. Wayment-Steele HK, et al. Among authors: participants e. Nucleic Acids Res. 2021 Oct 11;49(18):10604-10617. doi: 10.1093/nar/gkab764. Nucleic Acids Res. 2021. PMID: 34520542 Free PMC article.
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Leppek K, Byeon GW, Kladwang W, Wayment-Steele HK, Kerr CH, Xu AF, Kim DS, Topkar VV, Choe C, Rothschild D, Tiu GC, Wellington-Oguri R, Fujii K, Sharma E, Watkins AM, Nicol JJ, Romano J, Tunguz B, Participants E, Barna M, Das R. Leppek K, et al. Among authors: participants e. bioRxiv. 2021 Mar 30:2021.03.29.437587. doi: 10.1101/2021.03.29.437587. Preprint. bioRxiv. 2021. PMID: 33821271 Free PMC article. Updated.
Theoretical basis for stabilizing messenger RNA through secondary structure design.
Wayment-Steele HK, Kim DS, Choe CA, Nicol JJ, Wellington-Oguri R, Watkins AM, Sperberg RAP, Huang PS, Participants E, Das R. Wayment-Steele HK, et al. Among authors: participants e. bioRxiv. 2021 Feb 19:2020.08.22.262931. doi: 10.1101/2020.08.22.262931. Preprint. bioRxiv. 2021. PMID: 32869022 Free PMC article. Updated.
Deep learning models for predicting RNA degradation via dual crowdsourcing.
Wayment-Steele HK, Kladwang W, Watkins AM, Kim DS, Tunguz B, Reade W, Demkin M, Romano J, Wellington-Oguri R, Nicol JJ, Gao J, Onodera K, Fujikawa K, Mao H, Vandewiele G, Tinti M, Steenwinckel B, Ito T, Noumi T, He S, Ishi K, Lee Y, Öztürk F, Chiu A, Öztürk E, Amer K, Fares M, Participants E, Das R. Wayment-Steele HK, et al. Among authors: participants e. ArXiv. 2021 Oct 14:arXiv:2110.07531v2. Preprint. ArXiv. 2021. PMID: 34671698 Free PMC article. Updated.