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Showing results for parvin part i
Your search for Parvin Partoi retrieved no results
Syndecan-4 interacts directly with beta-parvin and regulates the ILK-PINCH-beta-parvin complex, the beta-parvin-beta-PIX-Rac1 axis, and cardiomyocyte geometry in a sex-dependent manner.
Mathiesen SB, Støle TP, Romaine A, Lunde M, Martinsen M, Aronsen JM, Sjaastad I, Louch WE, Christensen G, Carlson CR. Mathiesen SB, et al. Front Cell Dev Biol. 2025 Aug 29;13:1569185. doi: 10.3389/fcell.2025.1569185. eCollection 2025. Front Cell Dev Biol. 2025. PMID: 40977892 Free PMC article.
Smaller cardiomyocytes with elongation defects have been observed in animal models with beta-parvin deficiency, where the loss of this mechano-sensor disrupts the guanine nucleotide exchange factor (GEF) beta-PIX-GTPase Rac1 axis, which is essential for proper cell elongat …
Smaller cardiomyocytes with elongation defects have been observed in animal models with beta-parvin deficiency, where the loss of thi …
Risk Analysis for Quality Control Part 1: The Impact of Transition Assumptions in the Parvin Model.
Schmidt RL, Moore RA, Walker BS, Rudolf JW. Schmidt RL, et al. J Appl Lab Med. 2023 Jan 4;8(1):14-22. doi: 10.1093/jalm/jfac117. J Appl Lab Med. 2023. PMID: 36610423 Free article.
Recent approaches to QC have focused on the assessment of false-negative results. The Parvin model is the most-used model for risk analysis. The Parvin model assumes that the system makes a transition from an in-control to an out-of-control (OOC) state but makes no …
Recent approaches to QC have focused on the assessment of false-negative results. The Parvin model is the most-used model for risk an …
Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet. 2022 Feb 12;399(10325):665-676. doi: 10.1016/S0140-6736(22)00163-5. Lancet. 2022. PMID: 35151397 Free PMC article. Clinical Trial.
METHODS: RECOVERY is a randomised, controlled, open-label platform trial comparing several possible treatments with usual care in patients admitted to hospital with COVID-19. 127 UK hospitals took part in the evaluation of casirivimab and imdevimab. Eligible participants w …
METHODS: RECOVERY is a randomised, controlled, open-label platform trial comparing several possible treatments with usual care in patients a …
Infertility: Focus on the therapeutic potential of extracellular vesicles.
Parvin A, Erabi G, Mohammadpour D, Maleki-Kakelar H, Sadeghpour S, Pashaei MR, Taheri-Anganeh M, Ghasemnejad-Berenji H. Parvin A, et al. Reprod Biol. 2024 Sep;24(3):100925. doi: 10.1016/j.repbio.2024.100925. Epub 2024 Jul 16. Reprod Biol. 2024. PMID: 39018753 Review.
EVs (extracellular vesicles) transplantation has been shown in many studies to be a key part of regenerating different parts of the reproductive system, including the production of oocytes and the start of sperm production. ...
EVs (extracellular vesicles) transplantation has been shown in many studies to be a key part of regenerating different parts of the r …
Molnupiravir or nirmatrelvir-ritonavir plus usual care versus usual care alone in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group. RECOVERY Collaborative Group. Lancet Infect Dis. 2025 Sep;25(9):1000-1010. doi: 10.1016/S1473-3099(25)00093-3. Epub 2025 May 15. Lancet Infect Dis. 2025. PMID: 40383127 Free PMC article. Clinical Trial.
The molnupiravir comparison was conducted at 75 hospitals in the UK, two in Nepal, and two in Indonesia; the nirmatrelvir-ritonavir comparison was conducted at 32 hospitals in the UK. Participants could take part in both comparisons. The primary outcome was 28-day mortalit …
The molnupiravir comparison was conducted at 75 hospitals in the UK, two in Nepal, and two in Indonesia; the nirmatrelvir-ritonavir comparis …
New challenges in pseudopodial proteomics by a laser-assisted cell etching technique.
Mimae T, Ito A. Mimae T, et al. Biochim Biophys Acta. 2015 Jun;1854(6):538-46. doi: 10.1016/j.bbapap.2014.10.009. Epub 2014 Oct 18. Biochim Biophys Acta. 2015. PMID: 25461796 Review.
Using the excimer laser-assisted method, we showed that alpha-parvin, an actin-binding adaptor protein, is localized to pseudopodia, and is involved in breast cancer invasiveness. Our results clearly indicate that excimer laser-assisted cell etching is a useful technique f …
Using the excimer laser-assisted method, we showed that alpha-parvin, an actin-binding adaptor protein, is localized to pseudopodia, …
Risk Analysis for Quality Control Part 2: Theoretical Foundations for Risk Analysis.
Moore RA, Rudolf JW, Schmidt RL. Moore RA, et al. J Appl Lab Med. 2023 Jan 4;8(1):23-33. doi: 10.1093/jalm/jfac106. J Appl Lab Med. 2023. PMID: 36610426 Free article.
BACKGROUND: Risk analysis can be used to determine control limits for quality control (QC). The Parvin model is the most commonly used method for risk analysis; however; the Parvin model rests on assumptions that have been shown to produce paradoxical results and to …
BACKGROUND: Risk analysis can be used to determine control limits for quality control (QC). The Parvin model is the most commonly use …
Extracellular matrix remodelling in obesity and metabolic disorders.
Musale V, Wasserman DH, Kang L. Musale V, et al. Life Metab. 2023 Aug;2(4):load021. doi: 10.1093/lifemeta/load021. Epub 2023 May 26. Life Metab. 2023. PMID: 37383542 Free PMC article.
Increased ECM deposition contributes to the pathogenesis of insulin resistance at least in part through activation of cell surface integrin receptors and CD44 signalling cascades. ...These are the collagen-integrin receptor-IPP (ILK-PINCH-Parvin) axis and the hyalur …
Increased ECM deposition contributes to the pathogenesis of insulin resistance at least in part through activation of cell surface in …
PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival.
Fukuda T, Chen K, Shi X, Wu C. Fukuda T, et al. J Biol Chem. 2003 Dec 19;278(51):51324-33. doi: 10.1074/jbc.M309122200. Epub 2003 Oct 8. J Biol Chem. 2003. PMID: 14551191 Free article.
We report here the following. First, PINCH-1 and ILK, but not alpha-parvin, are essential for prompt cell spreading and motility. Second, PINCH-1 and ILK, like alpha-parvin, are crucial for cell survival. ...Fifth, PINCH-1, ILK and to a less extent alpha-parvin
We report here the following. First, PINCH-1 and ILK, but not alpha-parvin, are essential for prompt cell spreading and motility. Sec …
57 results