Patilea-Vrana GI[au] - Search Results

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Year	Number of Results
2017	1
2018	2
2019	2
2021	1
2022	1
2023	0

Page 1

Characterizing and Quantifying Extrahepatic Metabolism of (-)-Δ⁹-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, (±)-11-Hydroxy-Δ⁹-THC (11-OH-THC).

Kumar AR, Patilea-Vrana GI, Anoshchenko O, Unadkat JD. Kumar AR, et al. Among authors: patilea vrana gi. Drug Metab Dispos. 2022 Jun;50(6):734-740. doi: 10.1124/dmd.122.000868. Epub 2022 Apr 3. Drug Metab Dispos. 2022. PMID: 35370140

Hepatic Enzymes Relevant to the Disposition of (-)-∆⁹-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC.

Patilea-Vrana GI, Anoshchenko O, Unadkat JD. Patilea-Vrana GI, et al. Drug Metab Dispos. 2019 Mar;47(3):249-256. doi: 10.1124/dmd.118.085548. Epub 2018 Dec 19. Drug Metab Dispos. 2019. PMID: 30567877 Free PMC article.

Development and Verification of a Linked Δ ⁹-THC/11-OH-THC Physiologically Based Pharmacokinetic Model in Healthy, Nonpregnant Population and Extrapolation to Pregnant Women.

Patilea-Vrana GI, Unadkat JD. Patilea-Vrana GI, et al. Drug Metab Dispos. 2021 Jul;49(7):509-520. doi: 10.1124/dmd.120.000322. Epub 2021 May 5. Drug Metab Dispos. 2021. PMID: 33952608 Free PMC article.

Quantifying Hepatic Enzyme Kinetics of (-)-∆⁹-Tetrahydrocannabinol (THC) and Its Psychoactive Metabolite, 11-OH-THC, through In Vitro Modeling.

Patilea-Vrana GI, Unadkat JD. Patilea-Vrana GI, et al. Drug Metab Dispos. 2019 Jul;47(7):743-752. doi: 10.1124/dmd.119.086470. Epub 2019 May 2. Drug Metab Dispos. 2019. PMID: 31048453 Free PMC article.

When Does the Rate-Determining Step in the Hepatic Clearance of a Drug Switch from Sinusoidal Uptake to All Hepatobiliary Clearances? Implications for Predicting Drug-Drug Interactions.

Patilea-Vrana GI, Unadkat JD. Patilea-Vrana GI, et al. Drug Metab Dispos. 2018 Nov;46(11):1487-1496. doi: 10.1124/dmd.118.081307. Epub 2018 Aug 16. Drug Metab Dispos. 2018. PMID: 30115647 Free PMC article.

Development of a Novel Maternal-Fetal Physiologically Based Pharmacokinetic Model I: Insights into Factors that Determine Fetal Drug Exposure through Simulations and Sensitivity Analyses.

Zhang Z, Imperial MZ, Patilea-Vrana GI, Wedagedera J, Gaohua L, Unadkat JD. Zhang Z, et al. Among authors: patilea vrana gi. Drug Metab Dispos. 2017 Aug;45(8):920-938. doi: 10.1124/dmd.117.075192. Epub 2017 Jun 6. Drug Metab Dispos. 2017. PMID: 28588050 Free PMC article.

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