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Page 1
Structural mechanism of bridge RNA-guided recombination.
Hiraizumi M, Perry NT, Durrant MG, Soma T, Nagahata N, Okazaki S, Athukoralage JS, Isayama Y, Pai JJ, Pawluk A, Konermann S, Yamashita K, Hsu PD, Nishimasu H. Hiraizumi M, et al. Among authors: pawluk a. Nature. 2024 Jun;630(8018):994-1002. doi: 10.1038/s41586-024-07570-2. Epub 2024 Jun 26. Nature. 2024. PMID: 38926616 Free PMC article.
Bridge RNAs direct programmable recombination of target and donor DNA.
Durrant MG, Perry NT, Pai JJ, Jangid AR, Athukoralage JS, Hiraizumi M, McSpedon JP, Pawluk A, Nishimasu H, Konermann S, Hsu PD. Durrant MG, et al. Among authors: pawluk a. Nature. 2024 Jun;630(8018):984-993. doi: 10.1038/s41586-024-07552-4. Epub 2024 Jun 26. Nature. 2024. PMID: 38926615 Free PMC article.
Deep learning and CRISPR-Cas13d ortholog discovery for optimized RNA targeting.
Wei J, Lotfy P, Faizi K, Baungaard S, Gibson E, Wang E, Slabodkin H, Kinnaman E, Chandrasekaran S, Kitano H, Durrant MG, Duffy CV, Pawluk A, Hsu PD, Konermann S. Wei J, et al. Among authors: pawluk a. Cell Syst. 2023 Dec 20;14(12):1087-1102.e13. doi: 10.1016/j.cels.2023.11.006. Epub 2023 Dec 12. Cell Syst. 2023. PMID: 38091991 Free article.
Discovery of bioactive microbial gene products in inflammatory bowel disease.
Zhang Y, Bhosle A, Bae S, McIver LJ, Pishchany G, Accorsi EK, Thompson KN, Arze C, Wang Y, Subramanian A, Kearney SM, Pawluk A, Plichta DR, Rahnavard A, Shafquat A, Xavier RJ, Vlamakis H, Garrett WS, Krueger A, Huttenhower C, Franzosa EA. Zhang Y, et al. Among authors: pawluk a. Nature. 2022 Jun;606(7915):754-760. doi: 10.1038/s41586-022-04648-7. Epub 2022 May 25. Nature. 2022. PMID: 35614211 Free PMC article.
Bridge RNAs direct modular and programmable recombination of target and donor DNA.
Durrant MG, Perry NT, Pai JJ, Jangid AR, Athukoralage JS, Hiraizumi M, McSpedon JP, Pawluk A, Nishimasu H, Konermann S, Hsu PD. Durrant MG, et al. Among authors: pawluk a. bioRxiv [Preprint]. 2024 Jan 26:2024.01.24.577089. doi: 10.1101/2024.01.24.577089. bioRxiv. 2024. Update in: Nature. 2024 Jun;630(8018):984-993. doi: 10.1038/s41586-024-07552-4. PMID: 38328150 Free PMC article. Updated. Preprint.
Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes.
Thompson KN, Bonham KS, Ilott NE, Britton GJ, Colmenero P, Bullers SJ, McIver LJ, Ma S, Nguyen LH, Filer A, Brough I, Pearson C, Moussa C, Kumar V, Lam LH, Jackson MA, Pawluk A; Inflammatory Arthritis Microbiome Consortium (IAMC) investigators group; Kiriakidis S, Taylor PC, Wedderburn LR, Marsden B, Young SP, Littman DR, Faith JJ, Pratt AG, Bowness P, Raza K, Powrie F, Huttenhower C; IAMC. Thompson KN, et al. Among authors: pawluk a. Sci Transl Med. 2023 Jul 26;15(706):eabn4722. doi: 10.1126/scitranslmed.abn4722. Epub 2023 Jul 26. Sci Transl Med. 2023. PMID: 37494472
Breaking the Rules.
Pawluk A. Pawluk A. Cell. 2018 May 3;173(4):805-807. doi: 10.1016/j.cell.2018.04.011. Cell. 2018. PMID: 29727666 Free article. No abstract available.
Finding Common Ground.
Pawluk A. Pawluk A. Cell. 2019 May 30;177(6):1361-1363. doi: 10.1016/j.cell.2019.05.018. Cell. 2019. PMID: 31150613 Free article. No abstract available.
Anti-CRISPR: discovery, mechanism and function.
Pawluk A, Davidson AR, Maxwell KL. Pawluk A, et al. Nat Rev Microbiol. 2018 Jan;16(1):12-17. doi: 10.1038/nrmicro.2017.120. Epub 2017 Oct 24. Nat Rev Microbiol. 2018. PMID: 29062071 Review.
28 results