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Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial.
Verstovsek S, Mesa RA, Gotlib J, Gupta V, DiPersio JF, Catalano JV, Deininger MW, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH Jr, Arcasoy MO, Hexner EO, Lyons RM, Paquette R, Raza A, Jones M, Kornacki D, Sun K, Kantarjian H; COMFORT-I investigators. Verstovsek S, et al. J Hematol Oncol. 2017 Feb 22;10(1):55. doi: 10.1186/s13045-017-0417-z. J Hematol Oncol. 2017. PMID: 28228106 Free PMC article. Clinical Trial.
The secondary endpoints evaluated in this analysis were durability of a 35% reduction from baseline in spleen volume (spleen response) and overall survival, evaluated in the intent-to-treat population. Safety was evaluated in patients who received study treatment. RESULTS: …
The secondary endpoints evaluated in this analysis were durability of a 35% reduction from baseline in spleen volume (spleen response) and o …
Transforming Positive Pressure IR Suites to Treat COVID-19 Patients.
Lamparello NA, Choi S, Charalel R, Lee KS, Kesselman A, Scherer K, Harnain CM, Browne WF, Shiffman M, Holzwanger DJ, Pua BB. Lamparello NA, et al. J Vasc Interv Radiol. 2020 Sep;31(9):1496-1499. doi: 10.1016/j.jvir.2020.06.019. Epub 2020 Jun 30. J Vasc Interv Radiol. 2020. PMID: 32747141 Free PMC article. No abstract available.
Standardized Emblica officinalis fruit extract inhibited the activities of α-amylase, α-glucosidase, and dipeptidyl peptidase-4 and displayed antioxidant potential.
Majeed M, Majeed S, Mundkur L, Nagabhushanam K, Arumugam S, Beede K, Ali F. Majeed M, et al. J Sci Food Agric. 2020 Jan 30;100(2):509-516. doi: 10.1002/jsfa.10020. Epub 2019 Nov 13. J Sci Food Agric. 2020. PMID: 31487036 Free PMC article.
BACKGROUND: Emblica officinalis, known as amla in Ayurveda, has been used as a folk medicine to treat numerous pathological conditions, including diabetes. However, the novel extract of E. officinalis fruit extract (amla fruit extract, AFE, Saberry) containing 100 g kg(-1) …
BACKGROUND: Emblica officinalis, known as amla in Ayurveda, has been used as a folk medicine to treat numerous pathological condition …