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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1934 1
1955 1
1956 1
1965 1
1970 2
1982 2
1983 1
1984 2
1985 4
1986 3
1987 1
1988 2
1989 1
1990 3
1991 6
1992 1
1993 2
1995 3
1997 2
1998 3
1999 3
2000 2
2001 1
2002 3
2003 3
2004 3
2005 1
2006 3
2007 1
2008 2
2009 4
2010 2
2011 10
2012 9
2013 11
2014 9
2015 10
2016 8
2017 7
2018 8
2019 8
2020 8
2021 2
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145 results
Results by year
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Page 1
CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer.
Sanij E, Hannan KM, Xuan J, Yan S, Ahern JE, Trigos AS, Brajanovski N, Son J, Chan KT, Kondrashova O, Lieschke E, Wakefield MJ, Frank D, Ellis S, Cullinane C, Kang J, Poortinga G, Nag P, Deans AJ, Khanna KK, Mileshkin L, McArthur GA, Soong J, Berns EMJJ, Hannan RD, Scott CL, Sheppard KE, Pearson RB. Sanij E, et al. Among authors: pearson rb. Nat Commun. 2020 May 26;11(1):2641. doi: 10.1038/s41467-020-16393-4. Nat Commun. 2020. PMID: 32457376 Free PMC article.
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma.
AbuHammad S, Cullinane C, Martin C, Bacolas Z, Ward T, Chen H, Slater A, Ardley K, Kirby L, Chan KT, Brajanovski N, Smith LK, Rao AD, Lelliott EJ, Kleinschmidt M, Vergara IA, Papenfuss AT, Lau P, Ghosh P, Haupt S, Haupt Y, Sanij E, Poortinga G, Pearson RB, Falk H, Curtis DJ, Stupple P, Devlin M, Street I, Davies MA, McArthur GA, Sheppard KE. AbuHammad S, et al. Among authors: pearson rb. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17990-18000. doi: 10.1073/pnas.1901323116. Epub 2019 Aug 22. Proc Natl Acad Sci U S A. 2019. PMID: 31439820 Free PMC article.
Patient-derived Models of Abiraterone- and Enzalutamide-resistant Prostate Cancer Reveal Sensitivity to Ribosome-directed Therapy.
Lawrence MG, Obinata D, Sandhu S, Selth LA, Wong SQ, Porter LH, Lister N, Pook D, Pezaro CJ, Goode DL, Rebello RJ, Clark AK, Papargiris M, Van Gramberg J, Hanson AR, Banks P, Wang H, Niranjan B, Keerthikumar S, Hedwards S, Huglo A, Yang R, Henzler C, Li Y, Lopez-Campos F, Castro E, Toivanen R, Azad A, Bolton D, Goad J, Grummet J, Harewood L, Kourambas J, Lawrentschuk N, Moon D, Murphy DG, Sengupta S, Snow R, Thorne H, Mitchell C, Pedersen J, Clouston D, Norden S, Ryan A, Dehm SM, Tilley WD, Pearson RB, Hannan RD, Frydenberg M, Furic L, Taylor RA, Risbridger GP. Lawrence MG, et al. Among authors: pearson rb. Eur Urol. 2018 Nov;74(5):562-572. doi: 10.1016/j.eururo.2018.06.020. Epub 2018 Jul 23. Eur Urol. 2018. PMID: 30049486 Free PMC article.
Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis.
Parmenter TJ, Kleinschmidt M, Kinross KM, Bond ST, Li J, Kaadige MR, Rao A, Sheppard KE, Hugo W, Pupo GM, Pearson RB, McGee SL, Long GV, Scolyer RA, Rizos H, Lo RS, Cullinane C, Ayer DE, Ribas A, Johnstone RW, Hicks RJ, McArthur GA. Parmenter TJ, et al. Among authors: pearson rb. Cancer Discov. 2014 Apr;4(4):423-33. doi: 10.1158/2159-8290.CD-13-0440. Epub 2014 Jan 27. Cancer Discov. 2014. PMID: 24469106 Free PMC article.
Oncogene-induced senescence: From biology to therapy.
Zhu H, Blake S, Kusuma FK, Pearson RB, Kang J, Chan KT. Zhu H, et al. Among authors: pearson rb. Mech Ageing Dev. 2020 Apr;187:111229. doi: 10.1016/j.mad.2020.111229. Epub 2020 Mar 18. Mech Ageing Dev. 2020. PMID: 32171687 Review.
Therapeutic Approaches Targeting MYC-Driven Prostate Cancer.
Rebello RJ, Pearson RB, Hannan RD, Furic L. Rebello RJ, et al. Among authors: pearson rb. Genes (Basel). 2017 Feb 16;8(2):71. doi: 10.3390/genes8020071. Genes (Basel). 2017. PMID: 28212321 Free PMC article. Review.
Cystathionine β-Synthase in Physiology and Cancer.
Zhu H, Blake S, Chan KT, Pearson RB, Kang J. Zhu H, et al. Among authors: pearson rb. Biomed Res Int. 2018 Jun 28;2018:3205125. doi: 10.1155/2018/3205125. eCollection 2018. Biomed Res Int. 2018. PMID: 30050925 Free PMC article. Review.
Suppression of ABCE1-Mediated mRNA Translation Limits N-MYC-Driven Cancer Progression.
Gao J, Jung M, Mayoh C, Venkat P, Hannan KM, Fletcher JI, Kamili A, Gifford AJ, Kusnadi EP, Pearson RB, Hannan RD, Haber M, Norris MD, Somers K, Henderson MJ. Gao J, et al. Among authors: pearson rb. Cancer Res. 2020 Sep 1;80(17):3706-3718. doi: 10.1158/0008-5472.CAN-19-3914. Epub 2020 Jul 10. Cancer Res. 2020. PMID: 32651259
Targeting PI3 kinase/AKT/mTOR signaling in cancer.
Sheppard K, Kinross KM, Solomon B, Pearson RB, Phillips WA. Sheppard K, et al. Among authors: pearson rb. Crit Rev Oncog. 2012;17(1):69-95. doi: 10.1615/critrevoncog.v17.i1.60. Crit Rev Oncog. 2012. PMID: 22471665 Review.
Targeting the nucleolus for cancer intervention.
Quin JE, Devlin JR, Cameron D, Hannan KM, Pearson RB, Hannan RD. Quin JE, et al. Among authors: pearson rb. Biochim Biophys Acta. 2014 Jun;1842(6):802-16. doi: 10.1016/j.bbadis.2013.12.009. Epub 2014 Jan 2. Biochim Biophys Acta. 2014. PMID: 24389329 Free article. Review.
145 results
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