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Small RNAs are modified with N-glycans and displayed on the surface of living cells.
Flynn RA, Pedram K, Malaker SA, Batista PJ, Smith BAH, Johnson AG, George BM, Majzoub K, Villalta PW, Carette JE, Bertozzi CR. Flynn RA, et al. Among authors: pedram k. Cell. 2021 Jun 10;184(12):3109-3124.e22. doi: 10.1016/j.cell.2021.04.023. Epub 2021 May 17. Cell. 2021. PMID: 34004145 Free PMC article.
Revealing the human mucinome.
Malaker SA, Riley NM, Shon DJ, Pedram K, Krishnan V, Dorigo O, Bertozzi CR. Malaker SA, et al. Among authors: pedram k. Nat Commun. 2022 Jun 20;13(1):3542. doi: 10.1038/s41467-022-31062-4. Nat Commun. 2022. PMID: 35725833 Free PMC article.
Small molecule inhibitors of mammalian glycosylation.
Almahayni K, Spiekermann M, Fiore A, Yu G, Pedram K, Möckl L. Almahayni K, et al. Among authors: pedram k. Matrix Biol Plus. 2022 Mar 16;16:100108. doi: 10.1016/j.mbplus.2022.100108. eCollection 2022 Dec. Matrix Biol Plus. 2022. PMID: 36467541 Free PMC article.
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Pedram K, et al. Nat Biotechnol. 2023 Aug 3. doi: 10.1038/s41587-023-01840-6. Online ahead of print. Nat Biotechnol. 2023. PMID: 37537499
Quantitative Super-Resolution Microscopy of the Mammalian Glycocalyx.
Möckl L, Pedram K, Roy AR, Krishnan V, Gustavsson AK, Dorigo O, Bertozzi CR, Moerner WE. Möckl L, et al. Among authors: pedram k. Dev Cell. 2019 Jul 1;50(1):57-72.e6. doi: 10.1016/j.devcel.2019.04.035. Epub 2019 May 16. Dev Cell. 2019. PMID: 31105009 Free PMC article.
22 results