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1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia.
Pellegrini-Giampietro DE, Cozzi A, Peruginelli F, Leonardi P, Meli E, Pellicciari R, Moroni F. Pellegrini-Giampietro DE, et al. Among authors: peruginelli f. Eur J Neurosci. 1999 Oct;11(10):3637-47. doi: 10.1046/j.1460-9568.1999.00786.x. Eur J Neurosci. 1999. PMID: 10564371
Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: in vivo studies with (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a new potent and selective antagonist.
Cozzi A, Attucci S, Peruginelli F, Marinozzi M, Luneia R, Pellicciari R, Moroni F. Cozzi A, et al. Among authors: peruginelli f. Eur J Neurosci. 1997 Jul;9(7):1350-5. doi: 10.1111/j.1460-9568.1997.tb01489.x. Eur J Neurosci. 1997. PMID: 9240392