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Mcl-1 and tumor cell persistence.

Pfannenstiel LW, Gastman BR. Pfannenstiel LW, et al. Oncotarget. 2015 Jan 1;6(1):5-6. doi: 10.18632/oncotarget.3035. Oncotarget. 2015. PMID: 25575820 Free PMC article. No abstract available.

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Tumor-derived exosomes induce CD8⁺ T cell suppressors.

Maybruck BT, Pfannenstiel LW, Diaz-Montero M, Gastman BR. Maybruck BT, et al. Among authors: pfannenstiel lw. J Immunother Cancer. 2017 Aug 15;5(1):65. doi: 10.1186/s40425-017-0269-7. J Immunother Cancer. 2017. PMID: 28806909 Free PMC article.

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Immune-Checkpoint Blockade Opposes CD8⁺ T-cell Suppression in Human and Murine Cancer.

Pfannenstiel LW, Diaz-Montero CM, Tian YF, Scharpf J, Ko JS, Gastman BR. Pfannenstiel LW, et al. Cancer Immunol Res. 2019 Mar;7(3):510-525. doi: 10.1158/2326-6066.CIR-18-0054. Epub 2019 Feb 6. Cancer Immunol Res. 2019. PMID: 30728151 Free PMC article.

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Mcl-1 regulates reactive oxygen species via NOX4 during chemotherapy-induced senescence.

Demelash A, Pfannenstiel LW, Liu L, Gastman BR. Demelash A, et al. Among authors: pfannenstiel lw. Oncotarget. 2017 Apr 25;8(17):28154-28168. doi: 10.18632/oncotarget.15962. Oncotarget. 2017. PMID: 28423654 Free PMC article.

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Combination PD-1 blockade and irradiation of brain metastasis induces an effective abscopal effect in melanoma.

Pfannenstiel LW, McNeilly C, Xiang C, Kang K, Diaz-Montero CM, Yu JS, Gastman BR. Pfannenstiel LW, et al. Oncoimmunology. 2018 Oct 11;8(1):e1507669. doi: 10.1080/2162402X.2018.1507669. eCollection 2019. Oncoimmunology. 2018. PMID: 30546944 Free PMC article.

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Raiding the pharmacy: genomic screening identifies known chemotherapies as negative regulators of MCL1.

Pfannenstiel LW, Demelash A, Gastman BR. Pfannenstiel LW, et al. Genome Med. 2012 Jun 27;4(6):53. doi: 10.1186/gm352. Genome Med. 2012. PMID: 22742055 Free PMC article.

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Structure-Function Analysis of the Mcl-1 Protein Identifies a Novel Senescence-regulating Domain.

Demelash A, Pfannenstiel LW, Tannenbaum CS, Li X, Kalady MF, DeVecchio J, Gastman BR. Demelash A, et al. Among authors: pfannenstiel lw. J Biol Chem. 2015 Sep 4;290(36):21962-75. doi: 10.1074/jbc.M115.663898. Epub 2015 Jul 23. J Biol Chem. 2015. PMID: 26205817 Free PMC article.

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Interleukin-7 inhibits tumor-induced CD27-CD28- suppressor T cells: implications for cancer immunotherapy.

Zhang Y, Pfannenstiel LW, Bolesta E, Montes CL, Zhang X, Chapoval AI, Gartenhaus RB, Strome SE, Gastman BR. Zhang Y, et al. Among authors: pfannenstiel lw. Clin Cancer Res. 2011 Aug 1;17(15):4975-86. doi: 10.1158/1078-0432.CCR-10-3328. Epub 2011 Jun 28. Clin Cancer Res. 2011. PMID: 21712448 Free PMC article.

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Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice.

Pfannenstiel LW, Lam SS, Emens LA, Jaffee EM, Armstrong TD. Pfannenstiel LW, et al. Cell Immunol. 2010;263(1):79-87. doi: 10.1016/j.cellimm.2010.03.001. Epub 2010 Mar 6. Cell Immunol. 2010. PMID: 20346445 Free PMC article.

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Inhibition of Mcl-1 promotes senescence in cancer cells: implications for preventing tumor growth and chemotherapy resistance.

Bolesta E, Pfannenstiel LW, Demelash A, Lesniewski ML, Tobin M, Schlanger SE, Nallar SC, Papadimitriou JC, Kalvakolanu DV, Gastman BR. Bolesta E, et al. Among authors: pfannenstiel lw. Mol Cell Biol. 2012 May;32(10):1879-92. doi: 10.1128/MCB.06214-11. Epub 2012 Mar 26. Mol Cell Biol. 2012. PMID: 22451485 Free PMC article.

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