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Page 1
Regulator of G-protein signaling 18 controls both platelet generation and function.
Delesque-Touchard N, Pendaries C, Volle-Challier C, Millet L, Salel V, Hervé C, Pflieger AM, Berthou-Soulie L, Prades C, Sorg T, Herbert JM, Savi P, Bono F. Delesque-Touchard N, et al. Among authors: pflieger am. PLoS One. 2014 Nov 18;9(11):e113215. doi: 10.1371/journal.pone.0113215. eCollection 2014. PLoS One. 2014. PMID: 25405900 Free PMC article.
N-[6-(4-butanoyl-5-methyl-1H-pyrazol-1-yl)pyridazin-3-yl]-5-chloro-1-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1H-indole-3-carboxamide (SAR216471), a novel intravenous and oral, reversible, and directly acting P2Y12 antagonist.
Boldron C, Besse A, Bordes MF, Tissandié S, Yvon X, Gau B, Badorc A, Rousseaux T, Barré G, Meneyrol J, Zech G, Nazare M, Fossey V, Pflieger AM, Bonnet-Lignon S, Millet L, Briot C, Dol F, Hérault JP, Savi P, Lassalle G, Delesque N, Herbert JM, Bono F. Boldron C, et al. Among authors: pflieger am. J Med Chem. 2014 Sep 11;57(17):7293-316. doi: 10.1021/jm500588w. Epub 2014 Aug 25. J Med Chem. 2014. PMID: 25075638