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77 results

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LncRNA PGM5-AS1 Inhibits the Progression of Bladder Cancer by Regulating miR-587/SLIT3 Axis.
Duan X, Wang L, Wang Z, Wei W, Wang M, Ding D. Duan X, et al. Crit Rev Eukaryot Gene Expr. 2022;32(8):9-22. doi: 10.1615/CritRevEukaryotGeneExpr.2022042376. Crit Rev Eukaryot Gene Expr. 2022. PMID: 36017912
PGM5-AS1 overexpression significantly inhibited BC cell proliferation and migration, promoted apoptosis in vitro, and alleviated tumor growth in vivo. miR-587 has been shown to be a target of PGM5-AS1, and miR-587 overexpression can reverse the inhibitory effect of
PGM5-AS1 overexpression significantly inhibited BC cell proliferation and migration, promoted apoptosis in vitro, and alleviated tumo
LncRNA PGM5-AS1 inhibits non-small cell lung cancer progression by targeting miRNA-423-5p/SLIT2 axis.
Wang J, Ye J, Dang Y, Xu S. Wang J, et al. Cancer Cell Int. 2024 Jun 20;24(1):216. doi: 10.1186/s12935-024-03402-5. Cancer Cell Int. 2024. PMID: 38902704 Free PMC article.
Dysregulation of long non-coding RNAs (lncRNAs) has been shown to play an essential regulatory role in multiple cancers. However, the role of PGM5-AS1 in NSCLC remains unclear. Here, we found that PGM5-AS1 was down-regulated in NSCLC tissues and cells. ...Our rescue …
Dysregulation of long non-coding RNAs (lncRNAs) has been shown to play an essential regulatory role in multiple cancers. However, the role o …
PGM5-AS1 Promotes Progression of Diffuse Large B-Cell Lymphoma and Immune Escape by Regulating miR-503-5p.
Qin X, Li H, Wu J, Tang W, Li W, Li K. Qin X, et al. J Inflamm Res. 2024 Jul 1;17:4187-4197. doi: 10.2147/JIR.S453245. eCollection 2024. J Inflamm Res. 2024. PMID: 38973995 Free PMC article.
PURPOSE: Diffuse large B-cell lymphoma (DLBCL) is a prevalent malignant condition with a dismal prognosis. LncRNA PGM5 antisense RNA 1 (PGM5-AS1) appears to be intricately involved in the progression of DLBCL, yet the modulatory mechanism remains unclear. ...Our dis …
PURPOSE: Diffuse large B-cell lymphoma (DLBCL) is a prevalent malignant condition with a dismal prognosis. LncRNA PGM5 antisense RNA …
PGM5: a novel diagnostic and prognostic biomarker for liver cancer.
Jiao Y, Li Y, Jiang P, Han W, Liu Y. Jiao Y, et al. PeerJ. 2019 Jun 11;7:e7070. doi: 10.7717/peerj.7070. eCollection 2019. PeerJ. 2019. PMID: 31218127 Free PMC article.
Patents with low PGM5 levels had poorer overall survival and relapse-free survival. PGM5 was independently associated with patient prognosis. CONCLUSION: PGM5 has potential use as a diagnostic and prognostic biomarker for liver cancer....
Patents with low PGM5 levels had poorer overall survival and relapse-free survival. PGM5 was independently associated with pat …
Long non-coding RNAs PGM5-AS1 upregulates Decorin (DCN) to inhibit cervical cancer progression by sponging miR-4284.
Wang H, Wang D, Wei Q, Li C, Li C, Yang J. Wang H, et al. Bioengineered. 2022 Apr;13(4):9872-9884. doi: 10.1080/21655979.2022.2062088. Bioengineered. 2022. PMID: 35420507 Free PMC article.
Here, we investigated the function and mechanism of lncRNA PGM5-AS1 action in CC cells. Using real-time quantitative polymerase chain reaction or western blotting, PGM5-AS1 and decorin (DCN) were downregulated in CC tissues and cells, whereas miR-4284 was upregulate …
Here, we investigated the function and mechanism of lncRNA PGM5-AS1 action in CC cells. Using real-time quantitative polymerase chain …
PGM5 is a promising biomarker and may predict the prognosis of colorectal cancer patients.
Sun Y, Long H, Sun L, Sun X, Pang L, Chen J, Yi Q, Liang T, Shen Y. Sun Y, et al. Cancer Cell Int. 2019 Oct 1;19:253. doi: 10.1186/s12935-019-0967-y. eCollection 2019. Cancer Cell Int. 2019. PMID: 31582909 Free PMC article.
On the contrary, knockdown of PGM5 promotes the invasion and migration of CRC cells. CONCLUSIONS: PMG5 regulates proliferation, invasion, and migration in the CRC and decreased PGM5 is associated with poor prognosis. Therefore, PGM5 is a promising biomarker i …
On the contrary, knockdown of PGM5 promotes the invasion and migration of CRC cells. CONCLUSIONS: PMG5 regulates proliferation, invas …
PGM5-AS1 impairs miR-587-mediated GDF10 inhibition and abrogates progression of prostate cancer.
Du L, Gao Y. Du L, et al. J Transl Med. 2021 Jan 6;19(1):12. doi: 10.1186/s12967-020-02572-w. J Transl Med. 2021. PMID: 33407592 Free PMC article.
This study aims to clarify the inhibitory role of human PGM5 antisense RNA 1 (PGM5-AS1) in the proliferation and apoptosis of PCa cells. METHODS: The regulatory network of PGM5-AS1/microRNA-587 (miR-587)/growth and differentiation factor 10 (GDF10) axis was e …
This study aims to clarify the inhibitory role of human PGM5 antisense RNA 1 (PGM5-AS1) in the proliferation and apoptosis of …
Engineered exosomes for co-delivery of PGM5-AS1 and oxaliplatin to reverse drug resistance in colon cancer.
Hui B, Lu C, Wang J, Xu Y, Yang Y, Ji H, Li X, Xu L, Wang J, Tang W, Wang K, Gu Y. Hui B, et al. J Cell Physiol. 2022 Jan;237(1):911-933. doi: 10.1002/jcp.30566. Epub 2021 Aug 31. J Cell Physiol. 2022. PMID: 34463962
The results of this study show that the low expression of PGM5 antisense RNA 1 (PGM5-AS1) in colon cancer is induced by transcription inhibitor, GFI1B. ...Exosomes encapsulating oxaliplatin and PGM5-AS1 can reverse drug resistance. For identifying differentia …
The results of this study show that the low expression of PGM5 antisense RNA 1 (PGM5-AS1) in colon cancer is induced by transc …
Downregulation of PGM5 expression correlates with tumor progression and poor prognosis in human prostate cancer.
Sun J, Wang F, Zhou H, Zhao C, Li K, Fan C, Wang J. Sun J, et al. Discov Oncol. 2022 Jul 12;13(1):63. doi: 10.1007/s12672-022-00525-x. Discov Oncol. 2022. PMID: 35819729 Free PMC article.
Here, we reported that the expression of phosphoglucomutase-like protein 5 (PGM5) is significantly lower in prostate cancer tissue. The low expression of PGM5 and its related gene signature were found to be linked to poor clinical outcome and high Gleason score. ... …
Here, we reported that the expression of phosphoglucomutase-like protein 5 (PGM5) is significantly lower in prostate cancer tissue. T …
Reduced long noncoding RNA PGM5-AS1 facilitated proliferation and invasion of colorectal cancer through sponging miR-100-5p.
Zhou B, Yi F, Chen Y, Li CH, Cheng YS, Yang K. Zhou B, et al. Eur Rev Med Pharmacol Sci. 2020 Aug;24(15):7972-7981. doi: 10.26355/eurrev_202008_22480. Eur Rev Med Pharmacol Sci. 2020. PMID: 32767323 Free article.
The correlation between miR-100-5p and PGM5-AS1 was detected by statistical analysis. Bioinformatics prediction and Luciferase assay were performed to explore the interaction and binding site of PGM5-AS1 and miR-100-5p, miR-100-5p and SMAD4, respectively. RESULTS: W …
The correlation between miR-100-5p and PGM5-AS1 was detected by statistical analysis. Bioinformatics prediction and Luciferase assay …
77 results