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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1952 1
1957 1
1961 1
1963 1
1966 3
1967 2
1968 5
1969 3
1970 3
1972 1
1974 2
1976 1
1977 1
1980 4
1981 4
1983 2
1984 4
1985 2
1986 4
1988 1
1989 3
1990 3
1991 5
1992 4
1993 6
1994 3
1995 3
1996 5
1997 7
1998 4
1999 11
2000 12
2001 5
2002 5
2003 6
2004 8
2005 7
2006 17
2007 8
2008 10
2009 10
2010 13
2011 11
2012 9
2013 15
2014 12
2015 17
2016 15
2017 26
2018 21
2019 26
2020 23
2021 27
2022 35
2023 22
2024 12

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434 results

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Page 1
Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper.
Illuzzi G, Staniszewska AD, Gill SJ, Pike A, McWilliams L, Critchlow SE, Cronin A, Fawell S, Hawthorne G, Jamal K, Johannes J, Leonard E, Macdonald R, Maglennon G, Nikkilä J, O'Connor MJ, Smith A, Southgate H, Wilson J, Yates J, Cosulich S, Leo E. Illuzzi G, et al. Among authors: pike a. Clin Cancer Res. 2022 Nov 1;28(21):4724-4736. doi: 10.1158/1078-0432.CCR-22-0301. Clin Cancer Res. 2022. PMID: 35929986 Free PMC article.
The translational neural circuitry of anxiety.
Robinson OJ, Pike AC, Cornwell B, Grillon C. Robinson OJ, et al. Among authors: pike ac. J Neurol Neurosurg Psychiatry. 2019 Dec;90(12):1353-1360. doi: 10.1136/jnnp-2019-321400. Epub 2019 Jun 29. J Neurol Neurosurg Psychiatry. 2019. PMID: 31256001 Review.
Estrogen receptors: how do they signal and what are their targets.
Heldring N, Pike A, Andersson S, Matthews J, Cheng G, Hartman J, Tujague M, Ström A, Treuter E, Warner M, Gustafsson JA. Heldring N, et al. Among authors: pike a. Physiol Rev. 2007 Jul;87(3):905-31. doi: 10.1152/physrev.00026.2006. Physiol Rev. 2007. PMID: 17615392 Free article. Review.
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs.
Johannes JW, Balazs A, Barratt D, Bista M, Chuba MD, Cosulich S, Critchlow SE, Degorce SL, Di Fruscia P, Edmondson SD, Embrey K, Fawell S, Ghosh A, Gill SJ, Gunnarsson A, Hande SM, Heightman TD, Hemsley P, Illuzzi G, Lane J, Larner C, Leo E, Liu L, Madin A, Martin S, McWilliams L, O'Connor MJ, Orme JP, Pachl F, Packer MJ, Pei X, Pike A, Schimpl M, She H, Staniszewska AD, Talbot V, Underwood E, Varnes JG, Xue L, Yao T, Zhang K, Zhang AX, Zheng X. Johannes JW, et al. Among authors: pike a. J Med Chem. 2021 Oct 14;64(19):14498-14512. doi: 10.1021/acs.jmedchem.1c01012. Epub 2021 Sep 27. J Med Chem. 2021. PMID: 34570508
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1.
Staniszewska AD, Pilger D, Gill SJ, Jamal K, Bohin N, Guzzetti S, Gordon J, Hamm G, Mundin G, Illuzzi G, Pike A, McWilliams L, Maglennon G, Rose J, Hawthorne G, Cortes Gonzalez M, Halldin C, Johnström P, Schou M, Critchlow SE, Fawell S, Johannes JW, Leo E, Davies BR, Cosulich S, Sarkaria JN, O'Connor MJ, Hamerlik P. Staniszewska AD, et al. Among authors: pike a. Clin Cancer Res. 2024 Apr 1;30(7):1338-1351. doi: 10.1158/1078-0432.CCR-23-2094. Clin Cancer Res. 2024. PMID: 37967136
Pyridones in drug discovery: Recent advances.
Zhang Y, Pike A. Zhang Y, et al. Among authors: pike a. Bioorg Med Chem Lett. 2021 Apr 15;38:127849. doi: 10.1016/j.bmcl.2021.127849. Epub 2021 Feb 18. Bioorg Med Chem Lett. 2021. PMID: 33609656 Review.
Managing Canine Aggression in the Home.
Pike A. Pike A. Vet Clin North Am Small Anim Pract. 2018 May;48(3):387-402. doi: 10.1016/j.cvsm.2017.12.006. Epub 2018 Feb 9. Vet Clin North Am Small Anim Pract. 2018. PMID: 29429601 Review.
434 results