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Bis-(3-amino-2-pyridine) diselenide improves psychiatric disorders -atopic dermatitis comorbidity by regulating inflammatory and oxidative status in mice.

da Fonseca CAR, Dos Reis AS, Pinz MP, Peglow TJ, Schumacher RF, Perin G, Martins AWDS, Domingues WB, Campos VF, Soares MP, Roehrs JA, Luchese C, Wilhelm EA. da Fonseca CAR, et al. Among authors: pinz mp. Chem Biol Interact. 2021 Aug 25;345:109564. doi: 10.1016/j.cbi.2021.109564. Epub 2021 Jun 20. Chem Biol Interact. 2021. PMID: 34161785

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Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na⁺/K⁺-ATPase in an Alzheimer's disease model.

Pinz MP, Vogt AG, da Costa Rodrigues K, Dos Reis AS, Duarte LFB, Fronza MG, Domingues WB, Blodorn EB, Alves D, Campos VF, Savegnago L, Wilhelm EA, Luchese C. Pinz MP, et al. Metab Brain Dis. 2021 Jun;36(5):871-888. doi: 10.1007/s11011-021-00703-w. Epub 2021 Mar 2. Metab Brain Dis. 2021. PMID: 33651275

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Antioxidant compound (E)-2-benzylidene-4-phenyl-1,3-diselenole protects rats against thioacetamide-induced acute hepatotoxicity.

Reis AS, Pinz MP, Bortolatto CF, Jesse CR, Savegnago L, Roman S, Luchese C, Wilhelm EA. Reis AS, et al. Among authors: pinz mp. Can J Physiol Pharmacol. 2017 Sep;95(9):1039-1045. doi: 10.1139/cjpp-2016-0118. Epub 2017 Jul 13. Can J Physiol Pharmacol. 2017. PMID: 28704613

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Amnesia-ameliorative effect of a quinoline derivative through regulation of oxidative/cholinergic systems and Na⁺/K⁺-ATPase activity in mice.

Luchese C, Vogt AG, Pinz MP, Dos Reis AS, Gomes CB, Alves D, Wilhelm EA. Luchese C, et al. Among authors: pinz mp. Metab Brain Dis. 2020 Apr;35(4):589-600. doi: 10.1007/s11011-020-00535-0. Epub 2020 Feb 12. Metab Brain Dis. 2020. PMID: 32048104

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Synthesis of Isoxazolines by the Electrophilic Chalcogenation of β,γ-Unsaturated Oximes: Fishing Novel Anti-Inflammatory Agents.

Lopes EF, Penteado F, Thurow S, Pinz M, Reis AS, Wilhelm EA, Luchese C, Barcellos T, Dalberto B, Alves D, da Silva MS, Lenardão EJ. Lopes EF, et al. Among authors: pinz m. J Org Chem. 2019 Oct 4;84(19):12452-12462. doi: 10.1021/acs.joc.9b01754. Epub 2019 Sep 25. J Org Chem. 2019. PMID: 31509698

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Further analysis of acute antinociceptive and anti-inflammatory actions of 4-phenylselenyl-7-chloroquinoline in mice.

Silva VDG, Reis AS, Pinz MP, da Fonseca CAR, Duarte LFB, Roehrs JA, Alves D, Luchese C, Wilhelm EA. Silva VDG, et al. Among authors: pinz mp. Fundam Clin Pharmacol. 2017 Oct;31(5):513-525. doi: 10.1111/fcp.12295. Epub 2017 Jun 28. Fundam Clin Pharmacol. 2017. PMID: 28543930

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7-Chloro-4-(Phenylselanyl) Quinoline with Memory Enhancer Action in Aging Rats: Modulation of Neuroplasticity, Acetylcholinesterase Activity, and Cholesterol Levels.

Barth A, Vogt AG, Dos Reis AS, Pinz MP, Krüger R, Domingues WB, Alves D, Campos VF, Pinton S, Paroul N, Wilhelm EA, Luchese C. Barth A, et al. Among authors: pinz mp. Mol Neurobiol. 2019 Sep;56(9):6398-6408. doi: 10.1007/s12035-019-1530-5. Epub 2019 Feb 25. Mol Neurobiol. 2019. PMID: 30805835

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4-phenylselenyl-7-chloroquinoline, a novel multitarget compound with anxiolytic activity: Contribution of the glutamatergic system.

Reis AS, Pinz M, Duarte LFB, Roehrs JA, Alves D, Luchese C, Wilhelm EA. Reis AS, et al. Among authors: pinz m. J Psychiatr Res. 2017 Jan;84:191-199. doi: 10.1016/j.jpsychires.2016.10.007. Epub 2016 Oct 11. J Psychiatr Res. 2017. PMID: 27756019

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Polymeric nanocapsules as a technological alternative to reduce the toxicity caused by meloxicam in mice.

Villalba BT, Ianiski FR, Vogt AG, Pinz MP, Reis AS, Vaucher RA, Soares MP, Wilhelm EA, Luchese C. Villalba BT, et al. Among authors: pinz mp. Regul Toxicol Pharmacol. 2016 Nov;81:316-321. doi: 10.1016/j.yrtph.2016.09.023. Epub 2016 Sep 21. Regul Toxicol Pharmacol. 2016. PMID: 27664321

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Modulation of COX-2, INF-ɣ, glutamatergic and opioid systems contributes to antinociceptive, anti-inflammatory and anti-hyperalgesic effects of bis(3-amino-2-pyridine) diselenide.

Reis AS, Vogt AG, Pinz MP, Voss GT, da Fonseca CAR, Paltian JJ, Peglow TJ, Vaucher RA, Echenique JVZ, Soares MP, Schumacher RF, Perin G, Luchese C, Wilhelm EA. Reis AS, et al. Among authors: pinz mp. Chem Biol Interact. 2019 Sep 25;311:108790. doi: 10.1016/j.cbi.2019.108790. Epub 2019 Aug 7. Chem Biol Interact. 2019. PMID: 31400342

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