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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1996 2
1998 1
1999 3
2001 2
2002 4
2003 3
2004 3
2005 2
2009 2
2010 4
2011 6
2012 4
2013 4
2014 2
2015 2
2016 1
2017 6
2018 1
2019 2
2020 1
2021 6
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57 results
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Page 1
R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling.
Su R, Dong L, Li C, Nachtergaele S, Wunderlich M, Qing Y, Deng X, Wang Y, Weng X, Hu C, Yu M, Skibbe J, Dai Q, Zou D, Wu T, Yu K, Weng H, Huang H, Ferchen K, Qin X, Zhang B, Qi J, Sasaki AT, Plas DR, Bradner JE, Wei M, Marcucci G, Jiang X, Mulloy JC, Jin J, He C, Chen J. Su R, et al. Among authors: plas dr. Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14. Cell. 2018. PMID: 29249359 Free PMC article.
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis.
Qing Y, Dong L, Gao L, Li C, Li Y, Han L, Prince E, Tan B, Deng X, Wetzel C, Shen C, Gao M, Chen Z, Li W, Zhang B, Braas D, Ten Hoeve J, Sanchez GJ, Chen H, Chan LN, Chen CW, Ann D, Jiang L, Müschen M, Marcucci G, Plas DR, Li Z, Su R, Chen J. Qing Y, et al. Among authors: plas dr. Mol Cell. 2021 Mar 4;81(5):922-939.e9. doi: 10.1016/j.molcel.2020.12.026. Mol Cell. 2021. PMID: 33434505 Free PMC article.
The CD28 signaling pathway regulates glucose metabolism.
Frauwirth KA, Riley JL, Harris MH, Parry RV, Rathmell JC, Plas DR, Elstrom RL, June CH, Thompson CB. Frauwirth KA, et al. Among authors: plas dr. Immunity. 2002 Jun;16(6):769-77. doi: 10.1016/s1074-7613(02)00323-0. Immunity. 2002. PMID: 12121659 Free article.
Akt stimulates aerobic glycolysis in cancer cells.
Elstrom RL, Bauer DE, Buzzai M, Karnauskas R, Harris MH, Plas DR, Zhuang H, Cinalli RM, Alavi A, Rudin CM, Thompson CB. Elstrom RL, et al. Among authors: plas dr. Cancer Res. 2004 Jun 1;64(11):3892-9. doi: 10.1158/0008-5472.CAN-03-2904. Cancer Res. 2004. PMID: 15172999 Free article.
Tobacco smoking induces metabolic reprogramming of renal cell carcinoma.
Reigle J, Secic D, Biesiada J, Wetzel C, Shamsaei B, Chu J, Zang Y, Zhang X, Talbot NJ, Bischoff ME, Zhang Y, Thakar CV, Gaitonde K, Sidana A, Bui H, Cunningham JT, Zhang Q, Schmidt LS, Linehan WM, Medvedovic M, Plas DR, Figueroa JAL, Meller J, Czyzyk-Krzeska MF. Reigle J, et al. Among authors: plas dr. J Clin Invest. 2021 Jan 4;131(1):e140522. doi: 10.1172/JCI140522. J Clin Invest. 2021. PMID: 32970633 Free PMC article.
Pharmacologic Targeting of S6K1 in PTEN-Deficient Neoplasia.
Liu H, Feng X, Ennis KN, Behrmann CA, Sarma P, Jiang TT, Kofuji S, Niu L, Stratton Y, Thomas HE, Yoon SO, Sasaki AT, Plas DR. Liu H, et al. Among authors: plas dr. Cell Rep. 2017 Feb 28;18(9):2088-2095. doi: 10.1016/j.celrep.2017.02.022. Cell Rep. 2017. PMID: 28249155 Free PMC article.
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