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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1981 1
1982 1
1983 1
1984 2
1985 3
1989 2
1991 2
1997 1
2000 2
2002 2
2005 2
2006 4
2007 2
2008 3
2009 5
2010 3
2013 2
2014 1
2015 2
2016 4
2017 4
2018 4
2019 3
2020 5
2021 5
2022 2
2023 2
2024 4

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65 results

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Page 1
Information-Derived Mechanistic Hypotheses for Structural Cardiotoxicity.
Svensson F, Zoufir A, Mahmoud S, Afzal AM, Smit I, Giblin KA, Clements PJ, Mettetal JT, Pointon A, Harvey JS, Greene N, Williams RV, Bender A. Svensson F, et al. Among authors: pointon a. Chem Res Toxicol. 2018 Nov 19;31(11):1119-1127. doi: 10.1021/acs.chemrestox.8b00159. Epub 2018 Oct 17. Chem Res Toxicol. 2018. PMID: 30350600
Time for a Fully Integrated Nonclinical-Clinical Risk Assessment to Streamline QT Prolongation Liability Determinations: A Pharma Industry Perspective.
Vargas HM, Rolf MG, Wisialowski TA, Achanzar W, Bahinski A, Bass A, Benson CT, Chaudhary KW, Couvreur N, Dota C, Engwall MJ, Michael Foley C, Gallacher D, Greiter-Wilke A, Guillon JM, Guth B, Himmel HM, Hegele-Hartung C, Ito M, Jenkinson S, Chiba K, Lagrutta A, Levesque P, Martel E, Okai Y, Peri R, Pointon A, Qu Y, Teisman A, Traebert M, Yoshinaga T, Gintant GA, Leishman DJ, Valentin JP. Vargas HM, et al. Among authors: pointon a. Clin Pharmacol Ther. 2021 Feb;109(2):310-318. doi: 10.1002/cpt.2029. Epub 2020 Sep 24. Clin Pharmacol Ther. 2021. PMID: 32866317 Free PMC article. Review.
Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery.
Ewart L, Dehne EM, Fabre K, Gibbs S, Hickman J, Hornberg E, Ingelman-Sundberg M, Jang KJ, Jones DR, Lauschke VM, Marx U, Mettetal JT, Pointon A, Williams D, Zimmermann WH, Newham P. Ewart L, et al. Among authors: pointon a. Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:65-82. doi: 10.1146/annurev-pharmtox-010617-052722. Epub 2017 Oct 13. Annu Rev Pharmacol Toxicol. 2018. PMID: 29029591 Review.
Drug-induced myocardial dysfunction - recommendations for assessment in clinical and pre-clinical studies.
Ebrahimi A, Raichlen JS, Pointon A, Gottfridsson C, Munley J, Hockings P, Cartwright J, Buss N, Wikström J, Gan LM, Whittaker A, Khalil A, George RT, Garkaviy P, Brott D. Ebrahimi A, et al. Among authors: pointon a. Expert Opin Drug Saf. 2020 Mar;19(3):281-294. doi: 10.1080/14740338.2020.1731471. Epub 2020 Feb 25. Expert Opin Drug Saf. 2020. PMID: 32064957 Review.
On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships.
McAleer CW, Pointon A, Long CJ, Brighton RL, Wilkin BD, Bridges LR, Narasimhan Sriram N, Fabre K, McDougall R, Muse VP, Mettetal JT, Srivastava A, Williams D, Schnepper MT, Roles JL, Shuler ML, Hickman JJ, Ewart L. McAleer CW, et al. Among authors: pointon a. Sci Rep. 2019 Jul 3;9(1):9619. doi: 10.1038/s41598-019-45656-4. Sci Rep. 2019. PMID: 31270362 Free PMC article.
Preservation of cardiomyocytes from the adult heart.
Abi-Gerges N, Pointon A, Pullen GF, Morton MJ, Oldman KL, Armstrong D, Valentin JP, Pollard CE. Abi-Gerges N, et al. Among authors: pointon a. J Mol Cell Cardiol. 2013 Nov;64:108-19. doi: 10.1016/j.yjmcc.2013.09.004. Epub 2013 Sep 16. J Mol Cell Cardiol. 2013. PMID: 24051370
65 results