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Maintaining proteostasis under mechanical stress.

Höhfeld J, Benzing T, Bloch W, Fürst DO, Gehlert S, Hesse M, Hoffmann B, Hoppe T, Huesgen PF, Köhn M, Kolanus W, Merkel R, Niessen CM, Pokrzywa W, Rinschen MM, Wachten D, Warscheid B. Höhfeld J, et al. Among authors: pokrzywa w. EMBO Rep. 2021 Aug 4;22(8):e52507. doi: 10.15252/embr.202152507. Epub 2021 Jul 26. EMBO Rep. 2021. PMID: 34309183 Free PMC article. Review.

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Muscle-derived exophers promote reproductive fitness.

Turek M, Banasiak K, Piechota M, Shanmugam N, Macias M, Śliwińska MA, Niklewicz M, Kowalski K, Nowak N, Chacinska A, Pokrzywa W. Turek M, et al. Among authors: pokrzywa w. EMBO Rep. 2021 Aug 4;22(8):e52071. doi: 10.15252/embr.202052071. Epub 2021 Jul 20. EMBO Rep. 2021. PMID: 34288362 Free PMC article.

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The Dose-Dependent Pleiotropic Effects of the UBB⁺¹ Ubiquitin Mutant.

Banasiak K, Szulc NA, Pokrzywa W. Banasiak K, et al. Among authors: pokrzywa w. Front Mol Biosci. 2021 Mar 26;8:650730. doi: 10.3389/fmolb.2021.650730. eCollection 2021. Front Mol Biosci. 2021. PMID: 33842548 Free PMC article. Review.

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Ubiquitin Signaling Regulates RNA Biogenesis, Processing, and Metabolism.

Thapa P, Shanmugam N, Pokrzywa W. Thapa P, et al. Among authors: pokrzywa w. Bioessays. 2020 Jan;42(1):e1900171. doi: 10.1002/bies.201900171. Epub 2019 Nov 28. Bioessays. 2020. PMID: 31778250 Review.

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Ubiquitylation Pathways In Insulin Signaling and Organismal Homeostasis.

Balaji V, Pokrzywa W, Hoppe T. Balaji V, et al. Among authors: pokrzywa w. Bioessays. 2018 May;40(5):e1700223. doi: 10.1002/bies.201700223. Epub 2018 Apr 3. Bioessays. 2018. PMID: 29611634 Review.

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CHIPped balance of proteostasis and longevity.

Pokrzywa W, Hoppe T. Pokrzywa W, et al. Oncotarget. 2017 Oct 27;8(57):96472-96473. doi: 10.18632/oncotarget.22101. eCollection 2017 Nov 14. Oncotarget. 2017. PMID: 29228542 Free PMC article. No abstract available.

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Repair or destruction-an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasis.

Kevei É, Pokrzywa W, Hoppe T. Kevei É, et al. Among authors: pokrzywa w. FEBS Lett. 2017 Sep;591(17):2616-2635. doi: 10.1002/1873-3468.12750. Epub 2017 Jul 24. FEBS Lett. 2017. PMID: 28699655 Free PMC article. Review.

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CHIP ubiquitylates NOXA and induces its lysosomal degradation in response to DNA damage.

Albert MC, Brinkmann K, Pokrzywa W, Günther SD, Krönke M, Hoppe T, Kashkar H. Albert MC, et al. Among authors: pokrzywa w. Cell Death Dis. 2020 Sep 10;11(9):740. doi: 10.1038/s41419-020-02923-x. Cell Death Dis. 2020. PMID: 32913203 Free PMC article.

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Chaperone-directed ubiquitylation maintains proteostasis at the expense of longevity.

Pokrzywa W, Lorenz R, Hoppe T. Pokrzywa W, et al. Worm. 2017 Sep 5;6(2):e1371403. doi: 10.1080/21624054.2017.1371403. eCollection 2017. Worm. 2017. PMID: 28959501 Free PMC article.

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The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells.

Fatima A, Irmak D, Noormohammadi A, Rinschen MM, Das A, Leidecker O, Schindler C, Sánchez-Gaya V, Wagle P, Pokrzywa W, Hoppe T, Rada-Iglesias A, Vilchez D. Fatima A, et al. Among authors: pokrzywa w. Commun Biol. 2020 May 25;3(1):262. doi: 10.1038/s42003-020-0984-3. Commun Biol. 2020. PMID: 32451438 Free PMC article.

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