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TCRβ Sequencing Reveals Spatial and Temporal Evolution of Clonal CD4 T Cell Responses in a Breach of Tolerance Model of Inflammatory Arthritis.

Al Khabouri S, Benson RA, Prendergast CT, Gray JI, Otto TD, Brewer JM, Garside P. Al Khabouri S, et al. Among authors: prendergast ct. Front Immunol. 2021 Apr 27;12:669856. doi: 10.3389/fimmu.2021.669856. eCollection 2021. Front Immunol. 2021. PMID: 33986757 Free PMC article.

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Immune cell entry to central nervous system--current understanding and prospective therapeutic targets.

Prendergast CT, Anderton SM. Prendergast CT, et al. Endocr Metab Immune Disord Drug Targets. 2009 Dec;9(4):315-27. doi: 10.2174/187153009789839219. Endocr Metab Immune Disord Drug Targets. 2009. PMID: 20028334 Review.

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Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model.

Paape D, Prendergast CT, Price HP, Doehl JSP, Smith DF. Paape D, et al. Among authors: prendergast ct. Parasit Vectors. 2020 Mar 14;13(1):132. doi: 10.1186/s13071-020-3999-1. Parasit Vectors. 2020. PMID: 32171322 Free PMC article.

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Visualising the interaction of CD4 T cells and DCs in the evolution of inflammatory arthritis.

Prendergast CT, Patakas A, Al-Khabouri S, McIntyre CL, McInnes IB, Brewer JM, Garside P, Benson RA. Prendergast CT, et al. Ann Rheum Dis. 2018 Apr;77(4):579-588. doi: 10.1136/annrheumdis-2017-212279. Epub 2018 Jan 22. Ann Rheum Dis. 2018. PMID: 29358281

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Dissecting the molecular control of immune cell accumulation in the inflamed joint.

Prendergast CT, Benson RA, Scales HE, Bonilha CS, Cole JJ, McInnes I, Brewer JM, Garside P. Prendergast CT, et al. JCI Insight. 2022 Apr 8;7(7):e151281. doi: 10.1172/jci.insight.151281. JCI Insight. 2022. PMID: 35192549 Free PMC article.

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Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection.

Bourke CD, Prendergast CT, Sanin DE, Oulton TE, Hall RJ, Mountford AP. Bourke CD, et al. Among authors: prendergast ct. Int J Parasitol. 2015 Mar;45(4):215-24. doi: 10.1016/j.ijpara.2014.11.002. Epub 2015 Jan 6. Int J Parasitol. 2015. PMID: 25575749 Free PMC article.

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Exposure to inflammatory cytokines selectively limits GM-CSF production by induced T regulatory cells.

Reynolds BC, Turner DG, McPherson RC, Prendergast CT, Phelps RG, Turner NA, O'Connor RA, Anderton SM. Reynolds BC, et al. Among authors: prendergast ct. Eur J Immunol. 2014 Nov;44(11):3342-52. doi: 10.1002/eji.201444687. Epub 2014 Oct 1. Eur J Immunol. 2014. PMID: 25168419 Free PMC article.

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CD4+ T cell hyporesponsiveness after repeated exposure to Schistosoma mansoni larvae is dependent upon interleukin-10.

Prendergast CT, Sanin DE, Cook PC, Mountford AP. Prendergast CT, et al. Infect Immun. 2015 Apr;83(4):1418-30. doi: 10.1128/IAI.02831-14. Epub 2015 Jan 26. Infect Immun. 2015. PMID: 25624353 Free PMC article.

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CD4 T-cell hyporesponsiveness induced by schistosome larvae is not dependent upon eosinophils but may involve connective tissue mast cells.

Prendergast CT, Sanin DE, Mountford AP. Prendergast CT, et al. Parasite Immunol. 2016 Feb;38(2):81-92. doi: 10.1111/pim.12300. Parasite Immunol. 2016. PMID: 26679416 Free PMC article.

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Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4(+) T cells tolerized by peptide immunotherapy.

McPherson RC, Konkel JE, Prendergast CT, Thomson JP, Ottaviano R, Leech MD, Kay O, Zandee SE, Sweenie CH, Wraith DC, Meehan RR, Drake AJ, Anderton SM. McPherson RC, et al. Among authors: prendergast ct. Elife. 2014 Dec 29;3:e03416. doi: 10.7554/eLife.03416. Elife. 2014. PMID: 25546306 Free PMC article.

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