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Nonhomologous end joining: a good solution for bad ends.

Waters CA, Strande NT, Wyatt DW, Pryor JM, Ramsden DA. Waters CA, et al. Among authors: pryor jm. DNA Repair (Amst). 2014 May;17:39-51. doi: 10.1016/j.dnarep.2014.02.008. Epub 2014 Mar 14. DNA Repair (Amst). 2014. PMID: 24630899 Free PMC article. Review.

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Variations on a theme: eukaryotic Y-family DNA polymerases.

Washington MT, Carlson KD, Freudenthal BD, Pryor JM. Washington MT, et al. Among authors: pryor jm. Biochim Biophys Acta. 2010 May;1804(5):1113-23. doi: 10.1016/j.bbapap.2009.07.004. Epub 2009 Jul 17. Biochim Biophys Acta. 2010. PMID: 19616647 Free PMC article. Review.

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Structural snapshots of human DNA polymerase μ engaged on a DNA double-strand break.

Kaminski AM, Pryor JM, Ramsden DA, Kunkel TA, Pedersen LC, Bebenek K. Kaminski AM, et al. Among authors: pryor jm. Nat Commun. 2020 Sep 22;11(1):4784. doi: 10.1038/s41467-020-18506-5. Nat Commun. 2020. PMID: 32963245 Free PMC article.

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Enabling one-pot Golden Gate assemblies of unprecedented complexity using data-optimized assembly design.

Pryor JM, Potapov V, Kucera RB, Bilotti K, Cantor EJ, Lohman GJS. Pryor JM, et al. PLoS One. 2020 Sep 2;15(9):e0238592. doi: 10.1371/journal.pone.0238592. eCollection 2020. PLoS One. 2020. PMID: 32877448 Free PMC article.

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Ribonucleotide incorporation enables repair of chromosome breaks by nonhomologous end joining.

Pryor JM, Conlin MP, Carvajal-Garcia J, Luedeman ME, Luthman AJ, Small GW, Ramsden DA. Pryor JM, et al. Science. 2018 Sep 14;361(6407):1126-1129. doi: 10.1126/science.aat2477. Science. 2018. PMID: 30213916 Free PMC article.

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Mismatch discrimination and sequence bias during end-joining by DNA ligases.

Bilotti K, Potapov V, Pryor JM, Duckworth AT, Keck JL, Lohman GJS. Bilotti K, et al. Among authors: pryor jm. Nucleic Acids Res. 2022 May 6;50(8):4647-4658. doi: 10.1093/nar/gkac241. Nucleic Acids Res. 2022. PMID: 35438779 Free PMC article.

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Polμ tumor variants decrease the efficiency and accuracy of NHEJ.

Sastre-Moreno G, Pryor JM, Díaz-Talavera A, Ruiz JF, Ramsden DA, Blanco L. Sastre-Moreno G, et al. Among authors: pryor jm. Nucleic Acids Res. 2017 Sep 29;45(17):10018-10031. doi: 10.1093/nar/gkx625. Nucleic Acids Res. 2017. PMID: 28973441 Free PMC article.

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Regulation of human polλ by ATM-mediated phosphorylation during non-homologous end joining.

Sastre-Moreno G, Pryor JM, Moreno-Oñate M, Herrero-Ruiz AM, Cortés-Ledesma F, Blanco L, Ramsden DA, Ruiz JF. Sastre-Moreno G, et al. Among authors: pryor jm. DNA Repair (Amst). 2017 Mar;51:31-45. doi: 10.1016/j.dnarep.2017.01.004. Epub 2017 Jan 17. DNA Repair (Amst). 2017. PMID: 28109743 Free PMC article.

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Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu.

Moon AF, Pryor JM, Ramsden DA, Kunkel TA, Bebenek K, Pedersen LC. Moon AF, et al. Among authors: pryor jm. Nucleic Acids Res. 2017 Sep 6;45(15):9138-9148. doi: 10.1093/nar/gkx527. Nucleic Acids Res. 2017. PMID: 28911097 Free PMC article.

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Comprehensive Profiling of Four Base Overhang Ligation Fidelity by T4 DNA Ligase and Application to DNA Assembly.

Potapov V, Ong JL, Kucera RB, Langhorst BW, Bilotti K, Pryor JM, Cantor EJ, Canton B, Knight TF, Evans TC Jr, Lohman GJS. Potapov V, et al. Among authors: pryor jm. ACS Synth Biol. 2018 Nov 16;7(11):2665-2674. doi: 10.1021/acssynbio.8b00333. Epub 2018 Oct 29. ACS Synth Biol. 2018. PMID: 30335370 Free article.

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