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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2007 1
2010 1
2013 1
2014 3
2017 2
2018 2
2020 3
2021 5
2022 0
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17 results
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Page 1
LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody-Drug Conjugates.
Purcell JW, Tanlimco SG, Hickson J, Fox M, Sho M, Durkin L, Uziel T, Powers R, Foster K, McGonigal T, Kumar S, Samayoa J, Zhang D, Palma JP, Mishra S, Hollenbaugh D, Gish K, Morgan-Lappe SE, Hsi ED, Chao DT. Purcell JW, et al. Cancer Res. 2018 Jul 15;78(14):4059-4072. doi: 10.1158/0008-5472.CAN-18-0327. Epub 2018 May 15. Cancer Res. 2018. PMID: 29764866 Free article.
Evaluation of PNU-159682 antibody drug conjugates (ADCs).
Holte D, Lyssikatos JP, Valdiosera AM, Swinney Z, Sisodiya V, Sandoval J, Lee C, Aujay MA, Tchelepi RB, Hamdy OM, Gu C, Lin B, Sarvaiya H, Pysz MA, Laysang A, Williams S, Jun Lee D, Holda MK, Purcell JW, Gavrilyuk J. Holte D, et al. Among authors: purcell jw. Bioorg Med Chem Lett. 2020 Dec 15;30(24):127640. doi: 10.1016/j.bmcl.2020.127640. Epub 2020 Oct 28. Bioorg Med Chem Lett. 2020. PMID: 33127540
Targeting LRRC15 inhibits metastatic dissemination of ovarian cancer.
Ray U, Jung DB, Jin L, Xiao Y, Dasari S, Sarkar Bhattacharya S, Thirusangu P, Staub JK, Roy D, Roy B, Weroha SJ, Hou X, Purcell JW, Bakkum-Gamez JN, Kaufmann SH, Kannan N, Mitra AK, Shridhar V. Ray U, et al. Among authors: purcell jw. Cancer Res. 2021 Oct 15:canres.0622.2021. doi: 10.1158/0008-5472.CAN-21-0622. Online ahead of print. Cancer Res. 2021. PMID: 34654724 Free article.
Design, Synthesis, and Biological Investigation of Thailanstatin A and Spliceostatin D Analogues Containing Tetrahydropyran, Tetrahydrooxazine, and Fluorinated Structural Motifs.
Nicolaou KC, Rekula SR, Kumar SM, Podilapu AR, Matuszak RP, Jung PM, Lam LT, Phillips AC, Lyssikatos J, Munneke S, Gu C, Sarvaiya H, Sandoval J, Hammond M, Aujay M, Purcell JW, Reilly RM, Gavrilyuk J. Nicolaou KC, et al. Among authors: purcell jw. J Org Chem. 2021 Feb 5;86(3):2499-2521. doi: 10.1021/acs.joc.0c02643. Epub 2021 Jan 8. J Org Chem. 2021. PMID: 33417458
Streamlined Symmetrical Total Synthesis of Disorazole B1 and Design, Synthesis, and Biological Investigation of Disorazole Analogues.
Nicolaou KC, Krieger J, Murhade GM, Subramanian P, Dherange BD, Vourloumis D, Munneke S, Lin B, Gu C, Sarvaiaya H, Sandoval J, Zhang Z, Aujay M, Purcell JW, Gavrilyuk J. Nicolaou KC, et al. Among authors: purcell jw. J Am Chem Soc. 2020 Sep 9;142(36):15476-15487. doi: 10.1021/jacs.0c07094. Epub 2020 Aug 27. J Am Chem Soc. 2020. PMID: 32852944
NF-κB is a critical mediator of BRCA1-induced chemoresistance.
Harte MT, Gorski JJ, Savage KI, Purcell JW, Barros EM, Burn PM, McFarlane C, Mullan PB, Kennedy RD, Perkins ND, Harkin DP. Harte MT, et al. Among authors: purcell jw. Oncogene. 2014 Feb 6;33(6):713-723. doi: 10.1038/onc.2013.10. Epub 2013 Feb 25. Oncogene. 2014. PMID: 23435429 Free PMC article.
STAT1: a modulator of chemotherapy-induced apoptosis.
Thomas M, Finnegan CE, Rogers KM, Purcell JW, Trimble A, Johnston PG, Boland MP. Thomas M, et al. Among authors: purcell jw. Cancer Res. 2004 Nov 15;64(22):8357-64. doi: 10.1158/0008-5472.CAN-04-1864. Cancer Res. 2004. PMID: 15548705 Free article.
Design, Synthesis, and Biological Evaluation of Tubulysin Analogues, Linker-Drugs, and Antibody-Drug Conjugates, Insights into Structure-Activity Relationships, and Tubulysin-Tubulin Binding Derived from X-ray Crystallographic Analysis.
Nicolaou KC, Pan S, Pulukuri KK, Ye Q, Rigol S, Erande RD, Vourloumis D, Nocek BP, Munneke S, Lyssikatos J, Valdiosera A, Gu C, Lin B, Sarvaiaya H, Trinidad J, Sandoval J, Lee C, Hammond M, Aujay M, Taylor N, Pysz M, Purcell JW, Gavrilyuk J. Nicolaou KC, et al. Among authors: purcell jw. J Org Chem. 2021 Feb 19;86(4):3377-3421. doi: 10.1021/acs.joc.0c02755. Epub 2021 Feb 5. J Org Chem. 2021. PMID: 33544599
17 results