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1,4-Benzodiazepine peripheral cholecystokinin (CCK-A) receptor agonists.
Sherrill RG, Berman JM, Birkemo L, Croom DK, Dezube M, Ervin GN, Grizzle MK, James MK, Johnson MF, Queen KL, Rimele TJ, Vanmiddlesworth F, Sugg EE. Sherrill RG, et al. Among authors: queen kl. Bioorg Med Chem Lett. 2001 May 7;11(9):1145-8. doi: 10.1016/s0960-894x(01)00164-0. Bioorg Med Chem Lett. 2001. PMID: 11354363
Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity. 1. Optimization of the agonist "trigger".
Aquino CJ, Armour DR, Berman JM, Birkemo LS, Carr RA, Croom DK, Dezube M, Dougherty RW Jr, Ervin GN, Grizzle MK, Head JE, Hirst GC, James MK, Johnson MF, Miller LJ, Queen KL, Rimele TJ, Smith DN, Sugg EE. Aquino CJ, et al. Among authors: queen kl. J Med Chem. 1996 Jan 19;39(2):562-9. doi: 10.1021/jm950626d. J Med Chem. 1996. PMID: 8558528
Discovery of 1,5-benzodiazepines with peripheral cholecystokinin (CCK-A) receptor agonist activity (II): Optimization of the C3 amino substituent.
Hirst GC, Aquino C, Birkemo L, Croom DK, Dezube M, Dougherty RW Jr, Ervin GN, Grizzle MK, Henke B, James MK, Johnson MF, Momtahen T, Queen KL, Sherrill RG, Szewczyk J, Willson TM, Sugg EE. Hirst GC, et al. Among authors: queen kl. J Med Chem. 1996 Dec 20;39(26):5236-45. doi: 10.1021/jm9601664. J Med Chem. 1996. PMID: 8978852
16 results