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A(2A)R eGFP reporter mouse enables elucidation of A(2A)R expression dynamics during anti-tumor immune responses.
Todd KL, Lai J, Sek K, Huang YK, Newman DM, Derrick EB, Koay HF, Nguyen D, Hoang TX, Petley EV, Chan CW, Munoz I, House IG, Lee JN, Kim JS, Li J, Tong J, N de Menezes M, Scheffler CM, Yap KM, Chen AXY, Dunbar PA, Haugen B, Parish IA, Johnstone RW, Darcy PK, Beavis PA. Todd KL, et al. Nat Commun. 2023 Nov 1;14(1):6990. doi: 10.1038/s41467-023-42734-0. Nat Commun. 2023. PMID: 37914685 Free PMC article.
To overcome this limitation, here an A(2A)R eGFP reporter mouse is developed, enabling the expression of A(2A)R during ongoing anti-tumor immune responses to be assessed. ...In response to PD-L1 blockade, the emergence of PD-1(+)A(2A)R(-) cells correlates wit …
To overcome this limitation, here an A(2A)R eGFP reporter mouse is developed, enabling the expression of A(2A)R during ongoing …
Dexamethasone in Hospitalized Patients with Covid-19.
RECOVERY Collaborative Group; Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffery K, Montgomery A, Rowan K, Juszczak E, Baillie JK, Haynes R, Landray MJ. RECOVERY Collaborative Group, et al. N Engl J Med. 2021 Feb 25;384(8):693-704. doi: 10.1056/NEJMoa2021436. Epub 2020 Jul 17. N Engl J Med. 2021. PMID: 32678530 Free PMC article. Clinical Trial.
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.
Vervoort SJ, Welsh SA, Devlin JR, Barbieri E, Knight DA, Offley S, Bjelosevic S, Costacurta M, Todorovski I, Kearney CJ, Sandow JJ, Fan Z, Blyth B, McLeod V, Vissers JHA, Pavic K, Martin BP, Gregory G, Demosthenous E, Zethoven M, Kong IY, Hawkins ED, Hogg SJ, Kelly MJ, Newbold A, Simpson KJ, Kauko O, Harvey KF, Ohlmeyer M, Westermarck J, Gray N, Gardini A, Johnstone RW. Vervoort SJ, et al. Cell. 2021 Jun 10;184(12):3143-3162.e32. doi: 10.1016/j.cell.2021.04.022. Epub 2021 May 17. Cell. 2021. PMID: 34004147 Free PMC article.
Effects of preconception lifestyle intervention in infertile women with obesity: The FIT-PLESE randomized controlled trial.
Legro RS, Hansen KR, Diamond MP, Steiner AZ, Coutifaris C, Cedars MI, Hoeger KM, Usadi R, Johnstone EB, Haisenleder DJ, Wild RA, Barnhart KT, Mersereau J, Trussell JC, Krawetz SA, Kris-Etherton PM, Sarwer DB, Santoro N, Eisenberg E, Huang H, Zhang H; Reproductive Medicine Network. Legro RS, et al. PLoS Med. 2022 Jan 18;19(1):e1003883. doi: 10.1371/journal.pmed.1003883. eCollection 2022 Jan. PLoS Med. 2022. PMID: 35041662 Free PMC article. Clinical Trial.
PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity.
Djajawi TM, Pijpers L, Srivaths A, Chisanga D, Chan KF, Hogg SJ, Neil L, Rivera SM, Bartonicek N, Ellis SL, Lim Kam Sian TCC, Faridi P, Liao Y, Pal B, Behren A, Shi W, Vervoort SJ, Johnstone RW, Kearney CJ. Djajawi TM, et al. Cell Rep. 2024 Mar 26;43(3):113831. doi: 10.1016/j.celrep.2024.113831. Epub 2024 Feb 23. Cell Rep. 2024. PMID: 38401121 Free article.
The Staphylococcus aureus Network Adaptive Platform Trial Protocol: New Tools for an Old Foe.
Tong SYC, Mora J, Bowen AC, Cheng MP, Daneman N, Goodman AL, Heriot GS, Lee TC, Lewis RJ, Lye DC, Mahar RK, Marsh J, McGlothlin A, McQuilten Z, Morpeth SC, Paterson DL, Price DJ, Roberts JA, Robinson JO, van Hal SJ, Walls G, Webb SA, Whiteway L, Yahav D, Davis JS; Staphylococcus aureus Network Adaptive Platform (SNAP) Study Group. Tong SYC, et al. Clin Infect Dis. 2022 Nov 30;75(11):2027-2034. doi: 10.1093/cid/ciac476. Clin Infect Dis. 2022. PMID: 35717634 Free PMC article.
Erratum for the Research Article: "The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia" by G. Brumatti, C. Ma, N. Lalaoui, N.-Y. Nguyen, M. Navarro, M. C. Tanzer, J. Richmond, M. Ghisi, J. M. Salmon, N. Silke, G. Pomilio, S. P. Glaser, E. de Valle, R. Gugasyan, M. A. Gurthridge, S. M. Condon, R. W. Johnstone, R. Lock, G. Salvesen, A. Wei, D. L. Vaux, P. G. Ekert, J. Silke.
[No authors listed] [No authors listed] Sci Transl Med. 2017 May 31;9(392):eaan8181. doi: 10.1126/scitranslmed.aan8181. Sci Transl Med. 2017. PMID: 28566430 No abstract available.
Coronary CT Angiography and 5-Year Risk of Myocardial Infarction.
SCOT-HEART Investigators; Newby DE, Adamson PD, Berry C, Boon NA, Dweck MR, Flather M, Forbes J, Hunter A, Lewis S, MacLean S, Mills NL, Norrie J, Roditi G, Shah ASV, Timmis AD, van Beek EJR, Williams MC. SCOT-HEART Investigators, et al. N Engl J Med. 2018 Sep 6;379(10):924-933. doi: 10.1056/NEJMoa1805971. Epub 2018 Aug 25. N Engl J Med. 2018. PMID: 30145934 Free article. Clinical Trial.
Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models.
Hertz N, Chin R, Rakhit R, Ditsworth D, Wang C, Bartholomeus J, Liu S, Mody A, Laihsu A, Eastes A, Tai C, Kim R, Li J, Khasnavis S, Rafalski V, Heerendeen D, Garda V, Phung J, de Roulet D, Ordureau A, Harper JW, Johnstone S, Stöhr J. Hertz N, et al. Res Sq [Preprint]. 2024 May 10:rs.3.rs-4356493. doi: 10.21203/rs.3.rs-4356493/v1. Res Sq. 2024. PMID: 38765977 Free PMC article. Preprint.
54 results