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15 results

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Page 1
A Phase 1 Assessment of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of (2R,6R)-Hydroxynorketamine in Healthy Volunteers.
Raja SM, Guptill JT, Mack M, Peterson M, Byard S, Twieg R, Jordan L, Rich N, Castledine R, Bourne S, Wilmshurst M, Oxendine S, Avula SGC, Zuleta H, Quigley P, Lawson S, McQuaker SJ, Ahmadkhaniha R, Appelbaum LG, Kowalski K, Barksdale CT, Gufford BT, Awan A, Sancho AR, Moore MC, Berrada K, Cogan GB, DeLaRosa J, Radcliffe J, Pao M, Kennedy M, Lawrence Q, Goldfeder L, Amanfo L, Zanos P, Gilbert JR, Morris PJ, Moaddel R, Gould TD, Zarate CA Jr, Thomas CJ. Raja SM, et al. Clin Pharmacol Ther. 2024 Nov;116(5):1314-1324. doi: 10.1002/cpt.3391. Epub 2024 Jul 25. Clin Pharmacol Ther. 2024. PMID: 39054770 Free PMC article. Clinical Trial.
(R,S)-Ketamine (ketamine) is a dissociative anesthetic that also possesses analgesic and antidepressant activity. ...
(R,S)-Ketamine (ketamine) is a dissociative anesthetic that also possesses analgesic and antidepressant activity. ...
Senolytic effects of a modified Gingerenone A.
Moaddel R, Sanehira C, Keyes G, Cui CY, Ahmadkhaniha R, Candia J, Price NL, Eckroth S, Middleton B, Khadeer M, Mazucanti CH, McDevitt RA, Gorospe M, de Cabo R, Egan JM, Ramsden CE, Ferrucci L. Moaddel R, et al. NPJ Aging. 2025 May 30;11(1):45. doi: 10.1038/s41514-025-00230-3. NPJ Aging. 2025. PMID: 40447588 Free PMC article.
Lower folate levels in methamphetamine-induced psychosis: A cross-sectional study.
Hadizadeh H, Salehi M, Bozorgnia AR, Ahmadkhaniha HR. Hadizadeh H, et al. Drug Alcohol Depend. 2020 Feb 1;207:107682. doi: 10.1016/j.drugalcdep.2019.107682. Epub 2019 Oct 28. Drug Alcohol Depend. 2020. PMID: 31841749
The model demonstrated that every 1-unit increase in serum folate decreases the odds of presence of psychosis by 27% (R(2) = 53.5%, CI 12-64%, p = 0.006). The observed difference was not associated with the duration of METH use, patient's age at first METH use, or concurre …
The model demonstrated that every 1-unit increase in serum folate decreases the odds of presence of psychosis by 27% (R(2) = 53.5%, C …
Association of urinary bisphenol a concentration with type-2 diabetes mellitus.
Ahmadkhaniha R, Mansouri M, Yunesian M, Omidfar K, Jeddi MZ, Larijani B, Mesdaghinia A, Rastkari N. Ahmadkhaniha R, et al. J Environ Health Sci Eng. 2014 Mar 13;12(1):64. doi: 10.1186/2052-336X-12-64. J Environ Health Sci Eng. 2014. PMID: 24625016 Free PMC article.
A positive correlation between HbA1c and urinary BPA concentration was observed (r = 0.63, P = 0.001). CONCLUSIONS: Urinary Bisphenol A levels are found to be associated with diabetes independent of traditional diabetes risk factors. ...
A positive correlation between HbA1c and urinary BPA concentration was observed (r = 0.63, P = 0.001). CONCLUSIONS: Urinary Bisphenol …
Development and validation of a simple and sensitive HPLC-UV method for the determination of captopril in human plasma using a new derivatizing reagent 2-naphthyl propiolate.
Rastkari N, Khoobi M, Shafiee A, Khoshayand MR, Ahmadkhaniha R. Rastkari N, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Aug 1;932:144-51. doi: 10.1016/j.jchromb.2013.06.019. Epub 2013 Jun 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2013. PMID: 23831707
The achieved lower limit of quantification (LLOQ) was 3ng/mL; the assay exhibited a linear dynamic range of 3-2000ng/mL with correlation coefficient (r(2)) of 0.99. The precision was satisfactory in the whole calibration range with RSD of 5.9-12.4% (accuracy: from 97.5% to …
The achieved lower limit of quantification (LLOQ) was 3ng/mL; the assay exhibited a linear dynamic range of 3-2000ng/mL with correlation coe …
Magnetic solid-phase extraction based on magnetic multi-walled carbon nanotubes for the determination of polycyclic aromatic hydrocarbons in grilled meat samples.
Moazzen M, Ahmadkhaniha R, Gorji ME, Yunesian M, Rastkari N. Moazzen M, et al. Talanta. 2013 Oct 15;115:957-65. doi: 10.1016/j.talanta.2013.07.005. Epub 2013 Jul 9. Talanta. 2013. PMID: 24054688
Under optimized conditions, the LODs and LOQs achieved were in the range of 0.035-0.100 and 0.075-0.200 g Kg(-1) respectively. The calibration curves were linear (r(2) 0.988) over the concentration ranges from 0.100 g Kg(-1) to 250 g Kg(-1) The relative standard deviations …
Under optimized conditions, the LODs and LOQs achieved were in the range of 0.035-0.100 and 0.075-0.200 g Kg(-1) respectively. The calibrati …
Exposure assessment to trichloroethylene and perchloroethylene for workers in the dry cleaning industry.
Rastkari N, Yunesian M, Ahmadkhaniha R. Rastkari N, et al. Bull Environ Contam Toxicol. 2011 Apr;86(4):363-7. doi: 10.1007/s00128-011-0244-9. Epub 2011 Mar 17. Bull Environ Contam Toxicol. 2011. PMID: 21416139
The mean value of Perchloroethylene in breathing zone and the total Perchloroethylene uptake during the work shift of the three groups of dry-cleaning workers according to the capacity of the dry-cleaning machine (8, 12 and 18 kg) were 31.04, 50.87 and 120.99 mg m(-3) and 11.46, …
The mean value of Perchloroethylene in breathing zone and the total Perchloroethylene uptake during the work shift of the three groups of dr …
Sensitive determination of bisphenol A and bisphenol F in canned food using a solid-phase microextraction fibre coated with single-walled carbon nanotubes before GC/MS.
Rastkari N, Ahmadkhaniha R, Yunesian M, Baleh LJ, Mesdaghinia A. Rastkari N, et al. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010 Oct;27(10):1460-8. doi: 10.1080/19440049.2010.495730. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010. PMID: 20658403
Potential factors affecting the extraction efficiency, including extraction time, extraction temperature, desorption time, desorption temperature, and salinity were optimized. Calibration curves were linear (r(2)> or = 0.994) over the concentration range from 0.30 to 60 …
Potential factors affecting the extraction efficiency, including extraction time, extraction temperature, desorption time, desorption temper …
Magnetic solid-phase extraction based on magnetic multi-walled carbon nanotubes for the determination of phthalate monoesters in urine samples.
Rastkari N, Ahmadkhaniha R. Rastkari N, et al. J Chromatogr A. 2013 Apr 19;1286:22-8. doi: 10.1016/j.chroma.2013.02.070. Epub 2013 Feb 27. J Chromatogr A. 2013. PMID: 23510960
Under optimized conditions, the LODs and LOQs achieved were in the range of 0.025-0.050 and 0.125-0.250 ng mL(-1) respectively. And calibration curves were linear (r(2)0.992) over the concentration ranges from 0.250 to 250 ng mL(-1). In addition, a satisfying reproducibili …
Under optimized conditions, the LODs and LOQs achieved were in the range of 0.025-0.050 and 0.125-0.250 ng mL(-1) respectively. And calibrat …
Simultaneous determination of parathion, malathion, diazinon, and pirimiphos methyl in dried medicinal plants using solid-phase microextraction fibre coated with single-walled carbon nanotubes.
Ahmadkhaniha R, Samadi N, Salimi M, Sarkhail P, Rastkari N. Ahmadkhaniha R, et al. ScientificWorldJournal. 2012;2012:627607. doi: 10.1100/2012/627607. Epub 2012 May 2. ScientificWorldJournal. 2012. PMID: 22645439 Free PMC article.
For diazinon and pirimiphos methyl calibration, curves were linear (r(2) 0.993) over the concentration ranges from 1.5 to 300 ng g(-1), and the limit of detection at signal-to-noise ratio of 3 was 0.3 ng g(-1). For parathion and malathion, the linear range and limit of det …
For diazinon and pirimiphos methyl calibration, curves were linear (r(2) 0.993) over the concentration ranges from 1.5 to 300 ng g(-1 …
15 results