Spatial mapping of the brain metabolome lipidome and glycome.
Clarke HA, Ma X, Shedlock CJ, Medina T, Hawkinson TR, Wu L, Ribas RA, Keohane S, Ravi S, Bizon JL, Burke SN, Abisambra JF, Merritt ME, Prentice BM, Vander Kooi CW, Gentry MS, Chen L, Sun RC.
Clarke HA, et al.
Nat Commun. 2025 May 12;16(1):4373. doi: 10.1038/s41467-025-59487-7.
Nat Commun. 2025.
PMID: 40355410
Free PMC article.
This workflow integrates a computational platform, the Spatial Augmented Multiomics Interface (Sami), which enables multiomics integration, high-dimensional clustering, spatial anatomical mapping of matched molecular features, and metabolic pathway enrichment. To demonstra …
This workflow integrates a computational platform, the Spatial Augmented Multiomics Interface (Sami), which enables multiomics integr …