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Page 1
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
Structure-based drug discovery and antimicrobial activity of ciprofloxacin-grafted Ugi adducts.
Tahmasebi B, Iraji A, Sherafati M, Moazzam A, Akhlagh SA, Adib M, Mahdavi M. Tahmasebi B, et al. J Biomol Struct Dyn. 2023 Oct-Nov;41(17):8165-8174. doi: 10.1080/07391102.2022.2130985. Epub 2022 Oct 10. J Biomol Struct Dyn. 2023. PMID: 36214687
Among these derivatives, compound 7h with a 4-nitrophenyl substituent at R(2) exhibited significant activity against two tested Gram-positive bacteria with a minimum inhibitory concentration value of 0.097 g/mL while 7i bearing 4-chlorophenyl pendant demonstrated the best …
Among these derivatives, compound 7h with a 4-nitrophenyl substituent at R(2) exhibited significant activity against two tested Gram- …
Identification of key genes involved in secondary metabolite biosynthesis in Digitalis purpurea.
Amiri F, Moghadam A, Tahmasebi A, Niazi A. Amiri F, et al. PLoS One. 2023 Mar 9;18(3):e0277293. doi: 10.1371/journal.pone.0277293. eCollection 2023. PLoS One. 2023. PMID: 36893121 Free PMC article.
In spite of numerous omics experiments, most molecular mechanisms involved in metabolic pathways biosynthesis in D. purpurea remain unclear. Using R Package Weighted Gene Co-expression Network Analysis, co-expression analysis was performed on the transcriptome and metabolo …
In spite of numerous omics experiments, most molecular mechanisms involved in metabolic pathways biosynthesis in D. purpurea remain unclear. …
A comprehensive review of the botany, ethnopharmacology, phytochemistry, and pharmacological activities of two Iranian Rydingia species (Lamiaceae).
Tahmasebi A, Jamali B, Atabaki V, Sarker SD, Nahar L, Min HJ, Lee CW. Tahmasebi A, et al. Fitoterapia. 2024 Jul;176:106026. doi: 10.1016/j.fitote.2024.106026. Epub 2024 May 19. Fitoterapia. 2024. PMID: 38768794 Review.
Rydingia michauxii and R. persica, respectively, known as Kase Gol and Goldar in Persian, belong to the family Lamiaceae and they are well known herbal medicine in Iran for the treatment of various diseases, particularly diabetes. ...Only the search results that are associ …
Rydingia michauxii and R. persica, respectively, known as Kase Gol and Goldar in Persian, belong to the family Lamiaceae and they are …
Variation in essential oil composition of Rydingia michauxii at the three developmental stages.
Tahmasebi A, Hosseini SM, Karami A, Afsharifar A, Sharifi Olounabadi AR. Tahmasebi A, et al. Nat Prod Res. 2021 Jan;35(2):342-345. doi: 10.1080/14786419.2019.1622112. Epub 2019 May 29. Nat Prod Res. 2021. PMID: 31140321
In this study, the essential oil composition of Rydingia michauxii was evaluated during the dormant, vegetative and flowering stages. The major chemical constituents of R. michauxii at the dormant stage were eugenol (36.81%), eugenol acetate (21.02%), and carvacrol (9.35%) …
In this study, the essential oil composition of Rydingia michauxii was evaluated during the dormant, vegetative and flowering stages. The ma …
Medical education during the COVID-19 pandemic: lessons for the orthopedic departments.
Vahdati Z, Nematian H, Farhoud AR, Tahmasebi MN, Rahimi-Dehgolan S, Mortazavi SMJ, Kamrani RS, Zanjani LO, Golbakhsh MR, Seraj RN, Nabian MH. Vahdati Z, et al. BMC Med Educ. 2023 Jun 13;23(1):436. doi: 10.1186/s12909-023-04388-w. BMC Med Educ. 2023. PMID: 37312117 Free PMC article.
RESULTS: The maximum satisfaction for all three groups was observed in the platform and facilities for using e-classes, and the cost- and time-saving capabilities (Respectively, faculty members (FM): 81.8%, residents (R): 95.2%, students/interns (S/I): 87.0%; FM: 90.9%, …
RESULTS: The maximum satisfaction for all three groups was observed in the platform and facilities for using e-classes, and the cost- and ti …
A Meta-analysis of Transcriptome Data to Investigate the Effect of Soy Isoflavones on Breast Cancer Cell.
Ashrafi-Dehkordi E, Tahmasebi A, Zare H, Mazloomi SM. Ashrafi-Dehkordi E, et al. Iran J Biotechnol. 2024 Apr 1;22(2):e3762. doi: 10.30498/ijb.2024.407148.3762. eCollection 2024 Apr. Iran J Biotechnol. 2024. PMID: 39220340 Free PMC article.
In addition, we performed Gene Ontology (GO) enrichment analysis, pathway analysis, weighted gene co-expression network analysis (WGCNA) and recursive support vector machine (R-SVM) algorithm. RESULTS: Based on this meta-analysis, we identified 3,890 DEGs, of which 2,173 w …
In addition, we performed Gene Ontology (GO) enrichment analysis, pathway analysis, weighted gene co-expression network analysis (WGCNA) and …
Global genetic variations predict brain response to faces.
Dickie EW, Tahmasebi A, French L, Kovacevic N, Banaschewski T, Barker GJ, Bokde A, Büchel C, Conrod P, Flor H, Garavan H, Gallinat J, Gowland P, Heinz A, Ittermann B, Lawrence C, Mann K, Martinot JL, Nees F, Nichols T, Lathrop M, Loth E, Pausova Z, Rietschel M, Smolka MN, Ströhle A, Toro R, Schumann G, Paus T; IMAGEN consortium; IMAGEN consortium; IMAGEN consortium. Dickie EW, et al. PLoS Genet. 2014 Aug 14;10(8):e1004523. doi: 10.1371/journal.pgen.1004523. eCollection 2014 Aug. PLoS Genet. 2014. PMID: 25122193 Free PMC article.
Across the network, the strength of the genotype-phenotype relationship varied as a function of the inter-individual variability in the number of functional connections possessed by a given region (R(2) = 0.38, p<0.001). Furthermore, this variability showed an inverted …
Across the network, the strength of the genotype-phenotype relationship varied as a function of the inter-individual variability in the numb …
PIK3R3 is a candidate regulator of platelet count in people of Bangladeshi ancestry.
Burley K, Fitzgibbon L, van Heel D; Genes & Health Research Team@EastLondonGenes; Vuckovic D, Mumford AD; Genes & Health Research Team. Burley K, et al. Res Pract Thromb Haemost. 2023 May 14;7(4):100175. doi: 10.1016/j.rpth.2023.100175. eCollection 2023 May. Res Pract Thromb Haemost. 2023. PMID: 37538507 Free PMC article.
However, the Bangladeshi locus defined by rs946528 (chr1:46019890) did not associate with PLT in the Pakistani analysis but was in the same linkage disequilibrium block (r(2) 0.5) as PLT-associated variants in prior East Asian GWAS. The single independent association signa …
However, the Bangladeshi locus defined by rs946528 (chr1:46019890) did not associate with PLT in the Pakistani analysis but was in the same …
47 results