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hnRNP R promotes O-GlcNAcylation of eIF4G and facilitates axonal protein synthesis.
Zare A, Salehi S, Bader J, Schneider C, Fischer U, Veh A, Arampatzi P, Mann M, Briese M, Sendtner M. Zare A, et al. Nat Commun. 2024 Aug 28;15(1):7430. doi: 10.1038/s41467-024-51678-y. Nat Commun. 2024. PMID: 39198412 Free PMC article.
Mutant mice display denervated neuromuscular junctions and impaired motor behavior. In axons, hnRNP R is a component of translation initiation complexes and, through interaction with O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (Ogt), modulates O-GlcNAcylation …
Mutant mice display denervated neuromuscular junctions and impaired motor behavior. In axons, hnRNP R is a component of translation i …
337 results