Identification of genetic risk loci associated with aquaporin 4-positive neuromyelitis optica spectrum disorder: a genome-wide association study.
Attfield KE, Armen AP, Kuttikkatte SB, Farooq R, Francis AG, Dendrou CA, Leite MI, Waters P; International NMOSD Genetics Consortium; Weinshenker BG, Karczewski KJ, Neale BM, Jensen LT, Rossjohn J, Gold R, Korn T, McVean G, Palace J, Fugger L.
Attfield KE, et al.
Lancet Neurol. 2026 May;25(5):482-491. doi: 10.1016/S1474-4422(26)00084-0.
Lancet Neurol. 2026.
PMID: 42009010
Free article.
In Europeans, we identified variants that were either in linkage disequilibrium with or the same as those from the pan-ancestry study: rs1270942 (chr6:31951083:A>G, p=2.52 10(-28), OR 3.01, 95% CI 2.47-3.66), rs607929 (p=1.12 10(-20), OR 1.99, 95% CI 1.72-2.30), and rs3821 …
In Europeans, we identified variants that were either in linkage disequilibrium with or the same as those from the pan-ancestry study: rs127 …