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Page 1
Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines.
Ellrott K, Bailey MH, Saksena G, Covington KR, Kandoth C, Stewart C, Hess J, Ma S, Chiotti KE, McLellan M, Sofia HJ, Hutter C, Getz G, Wheeler D, Ding L; MC3 Working Group; Cancer Genome Atlas Research Network. Ellrott K, et al. Among authors: covington kr. Cell Syst. 2018 Mar 28;6(3):271-281.e7. doi: 10.1016/j.cels.2018.03.002. Cell Syst. 2018. PMID: 29596782 Free PMC article.
Gene expression profiling for metastatic risk in head and neck cutaneous squamous cell carcinoma.
Arron ST, Wysong A, Hall MA, Bailey CN, Covington KR, Kurley SJ, Goldberg MS, Kasprzak JM, Somani AK, Ibrahim SF, Brodland DG, Cleaver NJ, Maher IA, Xia Y, Koyfman SA, Newman JG. Arron ST, et al. Among authors: covington kr. Laryngoscope Investig Otolaryngol. 2022 Jan 6;7(1):135-144. doi: 10.1002/lio2.724. eCollection 2022 Feb. Laryngoscope Investig Otolaryngol. 2022. PMID: 35155791 Free PMC article.
Improved cutaneous melanoma survival stratification through integration of 31-gene expression profile testing with the American Joint Committee on Cancer 8th Edition Staging.
Wisco OJ, Marson JW, Litchman GH, Brownstone N, Covington KR, Martin BJ, Quick AP, Siegel JJ, Caruso HG, Cook RW, Winkelmann RR, Rigel DS. Wisco OJ, et al. Among authors: covington kr. Melanoma Res. 2022 Apr 1;32(2):98-102. doi: 10.1097/CMR.0000000000000804. Melanoma Res. 2022. PMID: 35254332 Free PMC article.
Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair.
Haradhvala NJ, Polak P, Stojanov P, Covington KR, Shinbrot E, Hess JM, Rheinbay E, Kim J, Maruvka YE, Braunstein LZ, Kamburov A, Hanawalt PC, Wheeler DA, Koren A, Lawrence MS, Getz G. Haradhvala NJ, et al. Among authors: covington kr. Cell. 2016 Jan 28;164(3):538-49. doi: 10.1016/j.cell.2015.12.050. Epub 2016 Jan 21. Cell. 2016. PMID: 26806129 Free PMC article.
Analyzing whole-genome sequences of 590 tumors from 14 different cancer types, we reveal widespread asymmetries across mutagenic processes, with transcriptional ("T-class") asymmetry dominating UV-, smoking-, and liver-cancer-associated mutations and replicative ("R-class" …
Analyzing whole-genome sequences of 590 tumors from 14 different cancer types, we reveal widespread asymmetries across mutagenic processes, …
Analytic validity of DecisionDx-Melanoma, a gene expression profile test for determining metastatic risk in melanoma patients.
Cook RW, Middlebrook B, Wilkinson J, Covington KR, Oelschlager K, Monzon FA, Stone JF. Cook RW, et al. Among authors: covington kr. Diagn Pathol. 2018 Feb 13;13(1):13. doi: 10.1186/s13000-018-0690-3. Diagn Pathol. 2018. PMID: 29433548 Free PMC article.
Inter-assay concordance on 168 specimens run on 2 consecutive days was 99% and matched probability scores were significantly correlated (R(2) = 0.96). Inter-instrument concordance was 95%, and probability scores had a correlation R(2) of 0.99 (p < 0.001). ...
Inter-assay concordance on 168 specimens run on 2 consecutive days was 99% and matched probability scores were significantly correlated ( …