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Commentary on "the E3 ubiquitin ligase Siah2 contributes to castration-resistant prostate cancer by regulation of androgen receptor transcriptional activity." Qi J, Tripathi M, Mishra R, Sahgal N, Fazli L, Ettinger S, Placzek WJ, Claps G, Chung LW, Bowtell D, Gleave M, Bhowmick N, Ronai ZA, Signal Transduction Program, Cancer Center, Sanford-Burnham Medical Research Institute, La Jolla, CA, USA.: Cancer Cell 2013;23(6):332-46.
Olumi AF. Olumi AF. Urol Oncol. 2014 Feb;32(2):210-1. doi: 10.1016/j.urolonc.2013.08.020. Urol Oncol. 2014. PMID: 24445292
PyVisualFields: A Python Package for Visual Field Analysis.
Eslami M, Kazeminasab S, Sharma V, Li Y, Fazli M, Wang M, Zebardast N, Elze T. Eslami M, et al. Transl Vis Sci Technol. 2023 Feb 1;12(2):6. doi: 10.1167/tvst.12.2.6. Transl Vis Sci Technol. 2023. PMID: 36745440 Free PMC article.
METHODS: For the first version, the R libraries for VF analysis provided by vfprogression and visualFields packages are analyzed to define the overlaps and distinct functions. ...Besides maintaining, the subsequent versions' milestones are established, and the third versio …
METHODS: For the first version, the R libraries for VF analysis provided by vfprogression and visualFields packages are analyzed to d …
Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression.
Ma T, Jin L, Bai S, Liu Z, Wang S, Shen B, Cho Y, Cao S, Sun MJS, Fazli L, Zhang D, Wedderburn C, Zhang DY, Mugon G, Ungerleider N, Baddoo M, Zhang K, Schiavone LH, Burkhardt BR, Fan J, You Z, Flemington EK, Dong X, Dong Y. Ma T, et al. J Natl Cancer Inst. 2024 Mar 7;116(3):421-433. doi: 10.1093/jnci/djad215. J Natl Cancer Inst. 2024. PMID: 37847647 Free PMC article.
Pretreatment with bisoprolol and vitamin E alone or in combination provides neuroprotection against cerebral ischemia/reperfusion injury in rats.
Salehi C, Seiiedy M, Soraya H, Fazli F, Ghasemnejad-Berenji M. Salehi C, et al. Naunyn Schmiedebergs Arch Pharmacol. 2021 Apr;394(4):685-695. doi: 10.1007/s00210-020-02007-9. Epub 2020 Oct 27. Naunyn Schmiedebergs Arch Pharmacol. 2021. PMID: 33106920
This study aimed to evaluate the neuroprotective effects of bisoprolol (biso) and vitamin E (vit E) treatment alone or in combination on cerebral ischemia/reperfusion (I/R) injury. A total of 30 male rats were divided randomly into five groups (n = 6), sham, I/R, I/ …
This study aimed to evaluate the neuroprotective effects of bisoprolol (biso) and vitamin E (vit E) treatment alone or in combination on cer …
Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer.
Al-Nakouzi N, Wang CK, Oo HZ, Nelepcu I, Lallous N, Spliid CB, Khazamipour N, Lo J, Truong S, Collins C, Hui D, Esfandnia S, Adomat H, Clausen TM, Gustavsson T, Choudhary S, Dagil R, Corey E, Wang Y, Chauchereau A, Fazli L, Esko JD, Salanti A, Nelson PS, Gleave ME, Daugaard M. Al-Nakouzi N, et al. Nat Commun. 2022 Aug 13;13(1):4760. doi: 10.1038/s41467-022-32530-7. Nat Commun. 2022. PMID: 35963852 Free PMC article.
Assessing Surface Shapes of the Optic Nerve Head and Peripapillary Retinal Nerve Fiber Layer in Glaucoma with Artificial Intelligence.
Saini C, Shen LQ, Pasquale LR, Boland MV, Friedman DS, Zebardast N, Fazli M, Li Y, Eslami M, Elze T, Wang M. Saini C, et al. Ophthalmol Sci. 2022 Apr 20;2(3):100161. doi: 10.1016/j.xops.2022.100161. eCollection 2022 Sep. Ophthalmol Sci. 2022. PMID: 36245761 Free PMC article.
Worse MD was associated most with higher coefficients of patterns 5, 4, and 9 (r = -0.16, r = -0.13, and r = -0.13, respectively), representing higher peripheral ONH and RNFL surfaces. In addition to established ONH summary parameters and 12-clock-hour RNFL t …
Worse MD was associated most with higher coefficients of patterns 5, 4, and 9 (r = -0.16, r = -0.13, and r = -0.13, res …
SRRM4 gene expression correlates with neuroendocrine prostate cancer.
Li Y, Zhang Q, Lovnicki J, Chen R, Fazli L, Wang Y, Gleave M, Huang J, Dong X. Li Y, et al. Prostate. 2019 Jan;79(1):96-104. doi: 10.1002/pros.23715. Epub 2018 Aug 28. Prostate. 2019. PMID: 30155992

Here, we report that SRRM4 in castrate-resistant tumors is highly expressed in NEPC, strongly correlated with SYP, CD56, and CHGA expressions (Pearson correlation r = 0.883, 0.675, and 0.881; P < 0.0001) and negatively correlated with AR and PSA expressions (Pearson cor

…
Here, we report that SRRM4 in castrate-resistant tumors is highly expressed in NEPC, strongly correlated with SYP, CD56, and CHGA expression …
Evasion of immunosurveillance by genomic alterations of PPARγ/RXRα in bladder cancer.
Korpal M, Puyang X, Jeremy Wu Z, Seiler R, Furman C, Oo HZ, Seiler M, Irwin S, Subramanian V, Julie Joshi J, Wang CK, Rimkunas V, Tortora D, Yang H, Kumar N, Kuznetsov G, Matijevic M, Chow J, Kumar P, Zou J, Feala J, Corson L, Henry R, Selvaraj A, Davis A, Bloudoff K, Douglas J, Kiss B, Roberts M, Fazli L, Black PC, Fekkes P, Smith PG, Warmuth M, Yu L, Hao MH, Larsen N, Daugaard M, Zhu P. Korpal M, et al. Nat Commun. 2017 Jul 24;8(1):103. doi: 10.1038/s41467-017-00147-w. Nat Commun. 2017. PMID: 28740126 Free PMC article.
Formulation and Pharmacokinetic Evaluation of Ethyl Cellulose/HPMC-Based Oral Expandable Sustained Release Dosage of Losartan Potassium.
Wani TU, Fazli AA, Raza SN, Khan NA, Sheikh FA. Wani TU, et al. AAPS PharmSciTech. 2022 Jun 8;23(5):160. doi: 10.1208/s12249-022-02295-9. AAPS PharmSciTech. 2022. PMID: 35676602
The plasma drug concentration-time curves obtained from the in vivo studies were used to determine pharmacokinetic parameters, such as area under the plasma drug concentration-time curve (AUC), area under first moment curve (AUMC), mean residence time (MRT), C(max), T(max), t(1/2 …
The plasma drug concentration-time curves obtained from the in vivo studies were used to determine pharmacokinetic parameters, such as area …
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