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Inference in generalized linear models with robustness to misspecified variances.
De Santis R, Goeman JJ, Davenport SJ, Hemerik J, Finos L. De Santis R, et al. Among authors: finos l. J Am Stat Assoc. 2025;120(552):2762-2771. doi: 10.1080/01621459.2025.2491775. Epub 2025 Jun 24. J Am Stat Assoc. 2025. PMID: 41488331 Free PMC article.
We illustrate the method using RNA sequencing count data, for which it is difficult to model the overdispersion correctly. The method is available in the R library flipscores....
We illustrate the method using RNA sequencing count data, for which it is difficult to model the overdispersion correctly. The method is ava …
β3AR-Dependent Brain-Derived Neurotrophic Factor (BDNF) Generation Limits Chronic Postischemic Heart Failure.
Cannavo A, Jun S, Rengo G, Marzano F, Agrimi J, Liccardo D, Elia A, Keceli G, Altobelli GG, Marcucci L, Megighian A, Gao E, Feng N, Kammers K, Ferrara N, Finos L, Koch WJ, Paolocci N. Cannavo A, et al. Among authors: finos l. Circ Res. 2023 Mar 31;132(7):867-881. doi: 10.1161/CIRCRESAHA.122.321583. Epub 2023 Mar 8. Circ Res. 2023. PMID: 36884028 Free PMC article.
Compared with wild type, isolated myoBDNF KO hearts displayed worse infarct size/LV dysfunction after I/R injury and modest benefits from LM22A-4. In vitro, LM22A-4 promoted neurite outgrowth and neovascularization, boosting myocyte function, effects reproduced by 7,8-dihy …
Compared with wild type, isolated myoBDNF KO hearts displayed worse infarct size/LV dysfunction after I/R injury and modest benefits …
Procrustes Analysis for High-Dimensional Data.
Andreella A, Finos L. Andreella A, et al. Among authors: finos l. Psychometrika. 2022 Dec;87(4):1422-1438. doi: 10.1007/s11336-022-09859-5. Epub 2022 May 18. Psychometrika. 2022. PMID: 35583747 Free PMC article.
The Procrustes-based perturbation model (Goodall in J R Stat Soc Ser B Methodol 53(2):285-321, 1991) allows minimization of the Frobenius distance between matrices by similarity transformation. ...
The Procrustes-based perturbation model (Goodall in J R Stat Soc Ser B Methodol 53(2):285-321, 1991) allows minimization of the Frobe …
Does exposure to reduced pH and diclofenac induce oxidative stress in marine bivalves? A comparative study with the mussel Mytilus galloprovincialis and the clam Ruditapes philippinarum.
Munari M, Matozzo V, Gagné F, Chemello G, Riedl V, Finos L, Pastore P, Badocco D, Marin MG. Munari M, et al. Among authors: finos l. Environ Pollut. 2018 Sep;240:925-937. doi: 10.1016/j.envpol.2018.05.005. Epub 2018 Jun 18. Environ Pollut. 2018. PMID: 29949844
Generally, due to increases in its antioxidant defence, M. galloprovincialis was more resistant than R. philippinarum to both diclofenac exposure and reduced pH. Conversely, reduced pH induced a significant decrease in COX activity in both the gills and digestive gland of …
Generally, due to increases in its antioxidant defence, M. galloprovincialis was more resistant than R. philippinarum to both diclofe …
Coping with seawater acidification and the emerging contaminant diclofenac at the larval stage: A tale from the clam Ruditapes philippinarum.
Munari M, Chemello G, Finos L, Ingrosso G, Giani M, Marin MG. Munari M, et al. Among authors: finos l. Chemosphere. 2016 Oct;160:293-302. doi: 10.1016/j.chemosphere.2016.06.095. Epub 2016 Jul 6. Chemosphere. 2016. PMID: 27391052
This study demonstrates a high susceptibility of R. philippinarum larvae to a slight reduction in seawater pH. Furthermore, the results obtained highlight that acidification enhances the sensitivity of clam larvae to environmentally relevant concentrations of diclofenac... …
This study demonstrates a high susceptibility of R. philippinarum larvae to a slight reduction in seawater pH. Furthermore, the resul …
Rotation-based multiple testing in the multivariate linear model.
Solari A, Finos L, Goeman JJ. Solari A, et al. Among authors: finos l. Biometrics. 2014 Dec;70(4):954-61. doi: 10.1111/biom.12238. Epub 2014 Sep 30. Biometrics. 2014. PMID: 25269416
Software to perform the procedure described in this article is available in the flip R package....
Software to perform the procedure described in this article is available in the flip R package....
FDR control with pseudo-gatekeeping based on a possibly data driven order of the hypotheses.
Farcomeni A, Finos L. Farcomeni A, et al. Among authors: finos l. Biometrics. 2013 Sep;69(3):606-13. doi: 10.1111/biom.12058. Epub 2013 Jul 11. Biometrics. 2013. PMID: 23844579
We conclude with an application to identification of molecular signatures of intracranial ependymoma. The methods are implemented in an R package (someMTP), freely available on CRAN....
We conclude with an application to identification of molecular signatures of intracranial ependymoma. The methods are implemented in an R …
k-FWER control without p -value adjustment, with application to detection of genetic determinants of multiple sclerosis in italian twins.
Finos L, Farcomeni A. Finos L, et al. Biometrics. 2011 Mar;67(1):174-81. doi: 10.1111/j.1541-0420.2010.01443.x. Biometrics. 2011. PMID: 20528862
We illustrate the method on an original study about gene discovery in multiple sclerosis, in which were involved a small number of couples of twins, discordant by disease. The methods are implemented in an R package (someKfwer), freely available on CRAN....
We illustrate the method on an original study about gene discovery in multiple sclerosis, in which were involved a small number of couples o …