Raab CE[au] - Search Results

Year	Number of Results
2002	2
2003	2
2004	3
2006	1
2007	1
2008	1
2009	1
2010	1
2020	1
2023	0

1

Integrating the Impact of Lipophilicity on Potency and Pharmacokinetic Parameters Enables the Use of Diverse Chemical Space during Small Molecule Drug Optimization.

Miller RR, Madeira M, Wood HB, Geissler WM, Raab CE, Martin IJ. Miller RR, et al. Among authors: raab ce. J Med Chem. 2020 Nov 12;63(21):12156-12170. doi: 10.1021/acs.jmedchem.9b01813. Epub 2020 Jul 7. J Med Chem. 2020. PMID: 32633947

2

Remote electronic control in the regioselective reduction of succinimides: a practical, scalable synthesis of Ep4 antagonist MF-310.

Molinaro C, Gauvreau D, Hughes G, Lau S, Lauzon S, Angelaud R, O'Shea PD, Janey J, Palucki M, Hoerrner SR, Raab CE, Sidler RR, Belley M, Han Y. Molinaro C, et al. Among authors: raab ce. J Org Chem. 2009 Sep 4;74(17):6863-6. doi: 10.1021/jo901267x. J Org Chem. 2009. PMID: 19663395

3

Synthesis of the first sulfur-35-labeled hERG radioligand.

Raab CE, Butcher JW, Connolly TM, Karczewski J, Yu NX, Staskiewicz SJ, Liverton N, Dean DC, Melillo DG. Raab CE, et al. Bioorg Med Chem Lett. 2006 Mar 15;16(6):1692-5. doi: 10.1016/j.bmcl.2005.12.021. Epub 2006 Jan 11. Bioorg Med Chem Lett. 2006. PMID: 16377185

4

A general and efficient 2-amination of pyridines and quinolines.

Yin J, Xiang B, Huffman MA, Raab CE, Davies IW. Yin J, et al. Among authors: raab ce. J Org Chem. 2007 Jun 8;72(12):4554-7. doi: 10.1021/jo070189y. Epub 2007 May 15. J Org Chem. 2007. PMID: 17500567

5

In vitro and in vivo metabolism of a novel cannabinoid-1 receptor inverse agonist, taranabant, in rats and monkeys.

Reddy VB, Doss GA, Karanam BV, Samuel K, Lanza TJ Jr, Lin LS, Yu NX, Zhang AS, Raab CE, Stearns RA, Kumar S. Reddy VB, et al. Among authors: raab ce. Xenobiotica. 2010 Sep;40(9):650-62. doi: 10.3109/00498254.2010.501117. Xenobiotica. 2010. PMID: 20608842

6

CYP2C75-involved autoinduction of metabolism in rhesus monkeys of methyl 3-chloro-3'-fluoro-4'-{(1R)-1-[({1-[(trifluoroacetyl)amino]cyclopropyl}carbonyl)amino]ethyl}-1,1'-biphenyl-2-carboxylate (MK-0686), a bradykinin B1 receptor antagonist.

Tang C, Carr BA, Poignant F, Ma B, Polsky-Fisher SL, Kuo Y, Strong-Basalyga K, Norcross A, Richards K, Eisenhandler R, Carlini EJ, Di Marco CN, Kuduk SD, Yu NX, Raab CE, Rushmore T, Frederick CB, Bock MG, Prueksaritanont T. Tang C, et al. Among authors: raab ce. J Pharmacol Exp Ther. 2008 Jun;325(3):935-46. doi: 10.1124/jpet.107.136044. Epub 2008 Feb 29. J Pharmacol Exp Ther. 2008. PMID: 18310472

7

Mechanism-based inhibition of human liver microsomal cytochrome P450 1A2 by zileuton, a 5-lipoxygenase inhibitor.

Lu P, Schrag ML, Slaughter DE, Raab CE, Shou M, Rodrigues AD. Lu P, et al. Among authors: raab ce. Drug Metab Dispos. 2003 Nov;31(11):1352-60. doi: 10.1124/dmd.31.11.1352. Drug Metab Dispos. 2003. PMID: 14570767

8

Pharmacological characterization and radioligand binding properties of a high-affinity, nonpeptide, bradykinin B1 receptor antagonist.

Ransom RW, Harrell CM, Reiss DR, Murphy KL, Chang RS, Hess JF, Miller PJ, O'Malley SS, Hey PJ, Kunapuli P, Su DS, Markowitz MK, Wallace MA, Raab CE, Jones AN, Dean DC, Pettibone DJ, Freidinger RM, Bock MG. Ransom RW, et al. Among authors: raab ce. Eur J Pharmacol. 2004 Sep 19;499(1-2):77-84. doi: 10.1016/j.ejphar.2004.07.104. Eur J Pharmacol. 2004. PMID: 15363953

9

Evaluation of ubiquinone concentration and mitochondrial function relative to cerivastatin-induced skeletal myopathy in rats.

Schaefer WH, Lawrence JW, Loughlin AF, Stoffregen DA, Mixson LA, Dean DC, Raab CE, Yu NX, Lankas GR, Frederick CB. Schaefer WH, et al. Among authors: raab ce. Toxicol Appl Pharmacol. 2004 Jan 1;194(1):10-23. doi: 10.1016/j.taap.2003.08.013. Toxicol Appl Pharmacol. 2004. PMID: 14728975

10

Comparative assessment of the ligand and metal ion binding properties of integrins alpha9beta1 and alpha4beta1.

Pepinsky RB, Mumford RA, Chen LL, Leone D, Amo SE, Riper GV, Whitty A, Dolinski B, Lobb RR, Dean DC, Chang LL, Raab CE, Si Q, Hagmann WK, Lingham RB. Pepinsky RB, et al. Among authors: raab ce. Biochemistry. 2002 Jun 4;41(22):7125-41. doi: 10.1021/bi020024d. Biochemistry. 2002. PMID: 12033947

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