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Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-occupied receptors.
Mol Pharmacol. 2003 Jul;64(1):21-31. doi: 10.1124/mol.64.1.21.
Mol Pharmacol. 2003.
PMID: 12815157
Elevation of ligand binding to muscarinic M(2) acetylcholine receptors by bis(ammonio)alkane-type allosteric modulators.
Raasch A, Scharfenstein O, Tränkle C, Holzgrabe U, Mohr K.
Raasch A, et al.
J Med Chem. 2002 Aug 15;45(17):3809-12. doi: 10.1021/jm020871e.
J Med Chem. 2002.
PMID: 12166953
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