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Page 1
De novo design of protein interactions with learned surface fingerprints.
Gainza P, Wehrle S, Van Hall-Beauvais A, Marchand A, Scheck A, Harteveld Z, Buckley S, Ni D, Tan S, Sverrisson F, Goverde C, Turelli P, Raclot C, Teslenko A, Pacesa M, Rosset S, Georgeon S, Marsden J, Petruzzella A, Liu K, Xu Z, Chai Y, Han P, Gao GF, Oricchio E, Fierz B, Trono D, Stahlberg H, Bronstein M, Correia BE. Gainza P, et al. Among authors: raclot c. Nature. 2023 May;617(7959):176-184. doi: 10.1038/s41586-023-05993-x. Epub 2023 Apr 26. Nature. 2023. PMID: 37100904 Free PMC article.
Broadly potent anti-SARS-CoV-2 antibody shares 93% of epitope with ACE2 and provides full protection in monkeys.
Fenwick C, Turelli P, Duhoo Y, Lau K, Herate C, Marlin R, Lamrayah M, Campos J, Esteves-Leuenberger L, Farina A, Raclot C, Genet V, Fiscalini F, Cesborn J, Perez L, Dereuddre-Bosquet N, Contreras V, Lheureux K, Relouzat F, Abdelnabi R, Leyssen P, Lévy Y, Pojer F, Le Grand R, Trono D, Pantaleo G. Fenwick C, et al. Among authors: raclot c. J Infect. 2023 Dec;87(6):524-537. doi: 10.1016/j.jinf.2023.10.008. Epub 2023 Oct 16. J Infect. 2023. PMID: 37852477 Free article.
S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity.
Mesquita FS, Abrami L, Sergeeva O, Turelli P, Qing E, Kunz B, Raclot C, Paz Montoya J, Abriata LA, Gallagher T, Dal Peraro M, Trono D, D'Angelo G, van der Goot FG. Mesquita FS, et al. Among authors: raclot c. Dev Cell. 2021 Oct 25;56(20):2790-2807.e8. doi: 10.1016/j.devcel.2021.09.016. Epub 2021 Oct 1. Dev Cell. 2021. PMID: 34599882 Free PMC article.
A highly potent antibody effective against SARS-CoV-2 variants of concern.
Fenwick C, Turelli P, Perez L, Pellaton C, Esteves-Leuenberger L, Farina A, Campos J, Lana E, Fiscalini F, Raclot C, Pojer F, Lau K, Demurtas D, Descatoire M, Joo VS, Foglierini M, Noto A, Abdelnabi R, Foo CS, Vangeel L, Neyts J, Du W, Bosch BJ, Veldman G, Leyssen P, Thiel V, LeGrand R, Lévy Y, Trono D, Pantaleo G. Fenwick C, et al. Among authors: raclot c. Cell Rep. 2021 Oct 12;37(2):109814. doi: 10.1016/j.celrep.2021.109814. Epub 2021 Sep 21. Cell Rep. 2021. PMID: 34599871 Free PMC article.
Patient-derived monoclonal antibody neutralizes SARS-CoV-2 Omicron variants and confers full protection in monkeys.
Fenwick C, Turelli P, Ni D, Perez L, Lau K, Herate C, Marlin R, Lana E, Pellaton C, Raclot C, Esteves-Leuenberger L, Campos J, Farina A, Fiscalini F, Dereuddre-Bosquet N, Relouzat F, Abdelnabi R, Foo CS, Neyts J, Leyssen P, Lévy Y, Pojer F, Stahlberg H, LeGrand R, Trono D, Pantaleo G. Fenwick C, et al. Among authors: raclot c. Nat Microbiol. 2022 Sep;7(9):1376-1389. doi: 10.1038/s41564-022-01198-6. Epub 2022 Jul 25. Nat Microbiol. 2022. PMID: 35879526 Free PMC article.
A high-throughput cell- and virus-free assay shows reduced neutralization of SARS-CoV-2 variants by COVID-19 convalescent plasma.
Fenwick C, Turelli P, Pellaton C, Farina A, Campos J, Raclot C, Pojer F, Cagno V, Nusslé SG, D'Acremont V, Fehr J, Puhan M, Pantaleo G, Trono D. Fenwick C, et al. Among authors: raclot c. Sci Transl Med. 2021 Aug 4;13(605):eabi8452. doi: 10.1126/scitranslmed.abi8452. Epub 2021 Jul 13. Sci Transl Med. 2021. PMID: 34257144 Free PMC article.
Seroprevalence of anti-SARS-CoV-2 antibodies and cross-variant neutralization capacity after the Omicron BA.2 wave in Geneva, Switzerland: a population-based study.
Zaballa ME, Perez-Saez J, de Mestral C, Pullen N, Lamour J, Turelli P, Raclot C, Baysson H, Pennacchio F, Villers J, Duc J, Richard V, Dumont R, Semaani C, Loizeau AJ, Graindorge C, Lorthe E, Balavoine JF, Pittet D, Schibler M, Vuilleumier N, Chappuis F, Kherad O, Azman AS, Posfay-Barbe KM, Kaiser L, Trono D, Stringhini S, Guessous I; Specchio-COVID19 study group. Zaballa ME, et al. Among authors: raclot c. Lancet Reg Health Eur. 2023 Jan;24:100547. doi: 10.1016/j.lanepe.2022.100547. Epub 2022 Dec 1. Lancet Reg Health Eur. 2023. PMID: 36474728 Free PMC article.
12 results