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Effect of capmatinib on the pharmacokinetics of digoxin and rosuvastatin administered as a 2-drug cocktail in patients with MET-dysregulated advanced solid tumours: A phase I, multicentre, open-label, single-sequence drug-drug interaction study.
Grande E, Giovannini M, Marriere E, Pultar P, Quinlan M, Chen X, Rahmanzadeh G, Curigliano G, Cui X. Grande E, et al. Among authors: rahmanzadeh g. Br J Clin Pharmacol. 2021 Jul;87(7):2867-2878. doi: 10.1111/bcp.14697. Epub 2020 Dec 29. Br J Clin Pharmacol. 2021. PMID: 33300203 Free PMC article. Clinical Trial.
Absorption, Distribution, Metabolism, and Excretion of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite.
Glaenzel U, Jin Y, Hansen R, Schroer K, Rahmanzadeh G, Pfaar U, Jaap van Lier J, Borell H, Meissner A, Camenisch G, Zhao S. Glaenzel U, et al. Among authors: rahmanzadeh g. Drug Metab Dispos. 2020 Oct;48(10):873-885. doi: 10.1124/dmd.119.090324. Epub 2020 Jul 14. Drug Metab Dispos. 2020. PMID: 32665418 Clinical Trial.