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Year Number of Results
2014 1
2015 1
2018 1
2020 10
2021 13
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Page 1
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing.
Riva L, Yuan S, Yin X, Martin-Sancho L, Matsunaga N, Pache L, Burgstaller-Muehlbacher S, De Jesus PD, Teriete P, Hull MV, Chang MW, Chan JF, Cao J, Poon VK, Herbert KM, Cheng K, Nguyen TH, Rubanov A, Pu Y, Nguyen C, Choi A, Rathnasinghe R, Schotsaert M, Miorin L, Dejosez M, Zwaka TP, Sit KY, Martinez-Sobrido L, Liu WC, White KM, Chapman ME, Lendy EK, Glynne RJ, Albrecht R, Ruppin E, Mesecar AD, Johnson JR, Benner C, Sun R, Schultz PG, Su AI, García-Sastre A, Chatterjee AK, Yuen KY, Chanda SK. Riva L, et al. Among authors: rathnasinghe r. Nature. 2020 Oct;586(7827):113-119. doi: 10.1038/s41586-020-2577-1. Epub 2020 Jul 24. Nature. 2020. PMID: 32707573 Free PMC article.
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling.
Miorin L, Kehrer T, Sanchez-Aparicio MT, Zhang K, Cohen P, Patel RS, Cupic A, Makio T, Mei M, Moreno E, Danziger O, White KM, Rathnasinghe R, Uccellini M, Gao S, Aydillo T, Mena I, Yin X, Martin-Sancho L, Krogan NJ, Chanda SK, Schotsaert M, Wozniak RW, Ren Y, Rosenberg BR, Fontoura BMA, García-Sastre A. Miorin L, et al. Among authors: rathnasinghe r. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28344-28354. doi: 10.1073/pnas.2016650117. Epub 2020 Oct 23. Proc Natl Acad Sci U S A. 2020. PMID: 33097660 Free PMC article.
Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models.
Yuin Ho JS, Wing-Yee Mok B, Campisi L, Jordan T, Yildiz S, Parameswaran S, Wayman JA, Gaudreault NN, Meekins DA, Indran SV, Morozov I, Trujillo JD, Fstkchyan YS, Rathnasinghe R, Zhu Z, Zheng S, Zhao N, White K, Ray-Jones H, Malysheva V, Thiecke MJ, Lau SY, Liu H, Junxia Zhang A, Chak-Yiu Lee A, Liu WC, Aydillo T, Salom Melo B, Guccione E, Sebra R, Shum E, Bakker J, Kaufman DA, Moreira AL, Carossino M, Balasuriya UBR, Byun M, Miraldi ER, Albrecht RA, Schotsaert M, Garcia-Sastre A, Chanda SK, Jeyasekharan AD, TenOever BR, Spivakov M, Weirauch MT, Heinz S, Chen H, Benner C, Richt JA, Marazzi I. Yuin Ho JS, et al. Among authors: rathnasinghe r. bioRxiv. 2020 Dec 1:2020.12.01.404483. doi: 10.1101/2020.12.01.404483. Preprint. bioRxiv. 2020. PMID: 33299999 Free PMC article. Updated.
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine.
Jangra S, De Vrieze J, Choi A, Rathnasinghe R, Laghlali G, Uvyn A, Van Herck S, Nuhn L, Deswarte K, Zhong Z, Sanders N, Lienenklaus S, David S, Strohmeier S, Amanat F, Krammer F, Hammad H, Lambrecht BN, Coughlan L, García-Sastre A, De Geest BG, Schotsaert M. Jangra S, et al. Among authors: rathnasinghe r. bioRxiv. 2020 Oct 23:2020.10.23.344085. doi: 10.1101/2020.10.23.344085. Preprint. bioRxiv. 2020. PMID: 33106810 Free PMC article. Updated.
Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection.
Kaul D, Rathnasinghe R, Ferres M, Tan GS, Barrera A, Pickett BE, Methe BA, Das SR, Budnik I, Halpin RA, Wentworth D, Schmolke M, Mena I, Albrecht RA, Singh I, Nelson KE, García-Sastre A, Dupont CL, Medina RA. Kaul D, et al. Among authors: rathnasinghe r. Nat Commun. 2020 May 21;11(1):2537. doi: 10.1038/s41467-020-16429-9. Nat Commun. 2020. PMID: 32439901 Free PMC article.
Scalable, effective, and rapid decontamination of SARS-CoV-2 contaminated N95 respirators using germicidal ultra-violet C (UVC) irradiation device.
Rathnasinghe R, Karlicek RF, Schotsaert M, Koffas MA, Arduini B, Jangra S, Wang B, Davis JL, Alnaggar M, Costa A, Vincent R, Garcia-Sastre A, Vashishth D, Balchandani P. Rathnasinghe R, et al. medRxiv. 2020 Oct 6:2020.10.05.20206953. doi: 10.1101/2020.10.05.20206953. Preprint. medRxiv. 2020. PMID: 33052360 Free PMC article.
Author Correction: Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection.
Kaul D, Rathnasinghe R, Ferres M, Tan GS, Barrera A, Pickett BE, Methe BA, Das SR, Budnik I, Halpin RA, Wentworth D, Schmolke M, Mena I, Albrecht RA, Singh I, Nelson KE, García-Sastre A, Dupont CL, Medina RA. Kaul D, et al. Among authors: rathnasinghe r. Nat Commun. 2020 Jun 16;11(1):3132. doi: 10.1038/s41467-020-17020-y. Nat Commun. 2020. PMID: 32546784 Free PMC article.
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