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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
2008 1
2009 2
2010 10
2011 9
2012 7
2013 3
2014 3
2015 5
2016 9
2017 7
2018 15
2019 9
2020 7
2021 3
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84 results
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Page 1
Targeting N-myristoylation for therapy of B-cell lymphomas.
Beauchamp E, Yap MC, Iyer A, Perinpanayagam MA, Gamma JM, Vincent KM, Lakshmanan M, Raju A, Tergaonkar V, Tan SY, Lim ST, Dong WF, Postovit LM, Read KD, Gray DW, Wyatt PG, Mackey JR, Berthiaume LG. Beauchamp E, et al. Among authors: read kd. Nat Commun. 2020 Oct 22;11(1):5348. doi: 10.1038/s41467-020-18998-1. Nat Commun. 2020. PMID: 33093447 Free PMC article.
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
BaragaƱa B, Forte B, Choi R, Nakazawa Hewitt S, Bueren-Calabuig JA, Pisco JP, Peet C, Dranow DM, Robinson DA, Jansen C, Norcross NR, Vinayak S, Anderson M, Brooks CF, Cooper CA, Damerow S, Delves M, Dowers K, Duffy J, Edwards TE, Hallyburton I, Horst BG, Hulverson MA, Ferguson L, JimƩnez-Dƭaz MB, Jumani RS, Lorimer DD, Love MS, Maher S, Matthews H, McNamara CW, Miller P, O'Neill S, Ojo KK, Osuna-Cabello M, Pinto E, Post J, Riley J, Rottmann M, Sanz LM, Scullion P, Sharma A, Shepherd SM, Shishikura Y, Simeons FRC, Stebbins EE, Stojanovski L, Straschil U, Tamaki FK, Tamjar J, Torrie LS, Vantaux A, Witkowski B, Wittlin S, Yogavel M, Zuccotto F, Angulo-Barturen I, Sinden R, Baum J, Gamo FJ, MƤser P, Kyle DE, Winzeler EA, Myler PJ, Wyatt PG, Floyd D, Matthews D, Sharma A, Striepen B, Huston CD, Gray DW, Fairlamb AH, Pisliakov AV, Walpole C, Read KD, Van Voorhis WC, Gilbert IH. BaragaƱa B, et al. Among authors: read kd. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7015-7020. doi: 10.1073/pnas.1814685116. Epub 2019 Mar 20. Proc Natl Acad Sci U S A. 2019. PMID: 30894487 Free PMC article.
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.
Wyllie S, Thomas M, Patterson S, Crouch S, De Rycker M, Lowe R, Gresham S, Urbaniak MD, Otto TD, Stojanovski L, Simeons FRC, Manthri S, MacLean LM, Zuccotto F, Homeyer N, Pflaumer H, Boesche M, Sastry L, Connolly P, Albrecht S, Berriman M, Drewes G, Gray DW, Ghidelli-Disse S, Dixon S, Fiandor JM, Wyatt PG, Ferguson MAJ, Fairlamb AH, Miles TJ, Read KD, Gilbert IH. Wyllie S, et al. Among authors: read kd. Nature. 2018 Aug;560(7717):192-197. doi: 10.1038/s41586-018-0356-z. Epub 2018 Jul 25. Nature. 2018. PMID: 30046105 Free PMC article.
Automated design of ligands to polypharmacological profiles.
Besnard J, Ruda GF, Setola V, Abecassis K, Rodriguiz RM, Huang XP, Norval S, Sassano MF, Shin AI, Webster LA, Simeons FR, Stojanovski L, Prat A, Seidah NG, Constam DB, Bickerton GR, Read KD, Wetsel WC, Gilbert IH, Roth BL, Hopkins AL. Besnard J, et al. Among authors: read kd. Nature. 2012 Dec 13;492(7428):215-20. doi: 10.1038/nature11691. Nature. 2012. PMID: 23235874 Free PMC article.
Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298).
Soares P, Gadd MS, Frost J, Galdeano C, Ellis L, Epemolu O, Rocha S, Read KD, Ciulli A. Soares P, et al. Among authors: read kd. J Med Chem. 2018 Jan 25;61(2):599-618. doi: 10.1021/acs.jmedchem.7b00675. Epub 2017 Sep 18. J Med Chem. 2018. PMID: 28853884 Free PMC article.
Setting Our Sights on Infectious Diseases.
De Rycker M, Horn D, Aldridge B, Amewu RK, Barry CE 3rd, Buckner FS, Cook S, Ferguson MAJ, Gobeau N, Herrmann J, Herrling P, Hope W, Keiser J, Lafuente-Monasterio MJ, Leeson PD, Leroy D, Manjunatha UH, McCarthy J, Miles TJ, Mizrahi V, Moshynets O, Niles J, Overington JP, Pottage J, Rao SPS, Read KD, Ribeiro I, Silver LL, Southern J, Spangenberg T, Sundar S, Taylor C, Van Voorhis W, White NJ, Wyllie S, Wyatt PG, Gilbert IH. De Rycker M, et al. Among authors: read kd. ACS Infect Dis. 2020 Jan 10;6(1):3-13. doi: 10.1021/acsinfecdis.9b00371. Epub 2019 Dec 6. ACS Infect Dis. 2020. PMID: 31808676 Free PMC article.
Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.
Giordani F, Paape D, Vincent IM, Pountain AW, FernƔndez-CortƩs F, Rico E, Zhang N, Morrison LJ, Freund Y, Witty MJ, Peter R, Edwards DY, Wilkes JM, van der Hooft JJJ, Regnault C, Read KD, Horn D, Field MC, Barrett MP. Giordani F, et al. Among authors: read kd. PLoS Pathog. 2020 Nov 3;16(11):e1008932. doi: 10.1371/journal.ppat.1008932. eCollection 2020 Nov. PLoS Pathog. 2020. PMID: 33141865 Free PMC article.
Substituted Aminoacetamides as Novel Leads for Malaria Treatment.
Norcross NR, Wilson C, BaragaƱa B, Hallyburton I, Osuna-Cabello M, Norval S, Riley J, Fletcher D, Sinden R, Delves M, Ruecker A, Duffy S, Meister S, Antonova-Koch Y, Crespo B, de CĆ³zar C, Sanz LM, Gamo FJ, Avery VM, Frearson JA, Gray DW, Fairlamb AH, Winzeler EA, Waterson D, Campbell SF, Willis PA, Read KD, Gilbert IH. Norcross NR, et al. Among authors: read kd. ChemMedChem. 2019 Jul 17;14(14):1329-1335. doi: 10.1002/cmdc.201900329. Epub 2019 Jul 3. ChemMedChem. 2019. PMID: 31188540 Free PMC article.
Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis.
Thomas MG, De Rycker M, Ajakane M, Crouch SD, Campbell L, Daugan A, Fra G, Guerrero C, Mackenzie CJ, MacLean L, Manthri S, Martin F, Norval S, Osuna-Cabello M, Riley J, Shishikura Y, Miguel-Siles J, Simeons FRC, Stojanovski L, Thomas J, Thompson S, Velasco RF, Fiandor JM, Wyatt PG, Read KD, Gilbert IH, Miles TJ. Thomas MG, et al. Among authors: read kd. RSC Med Chem. 2020 Aug 6;11(10):1168-1177. doi: 10.1039/d0md00203h. eCollection 2020 Oct 1. RSC Med Chem. 2020. PMID: 33479621 Free PMC article.
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