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Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis.

Ziegler PK, Bollrath J, Pallangyo CK, Matsutani T, Canli Ö, De Oliveira T, Diamanti MA, Müller N, Gamrekelashvili J, Putoczki T, Horst D, Mankan AK, Öner MG, Müller S, Müller-Höcker J, Kirchner T, Slotta-Huspenina J, Taketo MM, Reinheckel T, Dröse S, Larner AC, Wels WS, Ernst M, Greten TF, Arkan MC, Korn T, Wirth D, Greten FR. Ziegler PK, et al. Among authors: reinheckel t. Cell. 2018 Jun 28;174(1):88-101.e16. doi: 10.1016/j.cell.2018.05.028. Epub 2018 Jun 14. Cell. 2018. PMID: 29909986 Free PMC article.

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Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation.

Liszewski MK, Kolev M, Le Friec G, Leung M, Bertram PG, Fara AF, Subias M, Pickering MC, Drouet C, Meri S, Arstila TP, Pekkarinen PT, Ma M, Cope A, Reinheckel T, Rodriguez de Cordoba S, Afzali B, Atkinson JP, Kemper C. Liszewski MK, et al. Among authors: reinheckel t. Immunity. 2013 Dec 12;39(6):1143-57. doi: 10.1016/j.immuni.2013.10.018. Epub 2013 Dec 5. Immunity. 2013. PMID: 24315997 Free PMC article.

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Cathepsin D deficiency in mammary epithelium transiently stalls breast cancer by interference with mTORC1 signaling.

Ketterer S, Mitschke J, Ketscher A, Schlimpert M, Reichardt W, Baeuerle N, Hess ME, Metzger P, Boerries M, Peters C, Kammerer B, Brummer T, Steinberg F, Reinheckel T. Ketterer S, et al. Among authors: reinheckel t. Nat Commun. 2020 Oct 12;11(1):5133. doi: 10.1038/s41467-020-18935-2. Nat Commun. 2020. PMID: 33046706 Free PMC article.

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The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.

Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT. Halle A, et al. Among authors: reinheckel t. Nat Immunol. 2008 Aug;9(8):857-65. doi: 10.1038/ni.1636. Epub 2008 Jul 11. Nat Immunol. 2008. PMID: 18604209 Free PMC article.

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MMP14 empowers tumor-initiating breast cancer cells under hypoxic nutrient-depleted conditions.

Hillebrand LE, Wickberg SM, Gomez-Auli A, Follo M, Maurer J, Busch H, Boerries M, Reinheckel T. Hillebrand LE, et al. Among authors: reinheckel t. FASEB J. 2019 Mar;33(3):4124-4140. doi: 10.1096/fj.201801127R. Epub 2018 Dec 6. FASEB J. 2019. PMID: 30521382

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Cathepsin B as a potential cystatin M/E target in the mouse hair follicle.

Oortveld MAW, van Vlijmen-Willems IMJJ, Kersten FFJ, Cheng T, Verdoes M, van Erp PEJ, Verbeek S, Reinheckel T, Hendriks WJAJ, Schalkwijk J, Zeeuwen PLJM. Oortveld MAW, et al. Among authors: reinheckel t. FASEB J. 2017 Oct;31(10):4286-4294. doi: 10.1096/fj.201700267R. Epub 2017 Jun 8. FASEB J. 2017. PMID: 28596234 Free PMC article.

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New Kid on the Block.

Reinheckel T. Reinheckel T. Theranostics. 2017 Jul 30;7(11):2965-2967. doi: 10.7150/thno.21603. eCollection 2017. Theranostics. 2017. PMID: 28824729 Free PMC article.

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The role of proteases in epithelial-to-mesenchymal cell transitions in cancer.

Mitschke J, Burk UC, Reinheckel T. Mitschke J, et al. Among authors: reinheckel t. Cancer Metastasis Rev. 2019 Sep;38(3):431-444. doi: 10.1007/s10555-019-09808-2. Cancer Metastasis Rev. 2019. PMID: 31482486 Review.

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Impact of proteolysis on cancer stem cell functions.

Hillebrand LE, Reinheckel T. Hillebrand LE, et al. Among authors: reinheckel t. Biochimie. 2019 Nov;166:214-222. doi: 10.1016/j.biochi.2019.03.002. Epub 2019 Mar 12. Biochimie. 2019. PMID: 30876968 Review.

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Lysosomal processing of progranulin.

Zhou X, Paushter DH, Feng T, Sun L, Reinheckel T, Hu F. Zhou X, et al. Among authors: reinheckel t. Mol Neurodegener. 2017 Aug 23;12(1):62. doi: 10.1186/s13024-017-0205-9. Mol Neurodegener. 2017. PMID: 28835281 Free PMC article.

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