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IL-4-dependent Jagged1 expression/processing is associated with survival of chronic lymphocytic leukemia cells but not with Notch activation.
De Falco F, Del Papa B, Baldoni S, Sabatini R, Falzetti F, Di Ianni M, Martelli MP, Mezzasoma F, Pelullo M, Marconi P, Sportoletti P, Screpanti I, Rosati E. De Falco F, et al. Among authors: sabatini r. Cell Death Dis. 2018 Nov 26;9(12):1160. doi: 10.1038/s41419-018-1185-6. Cell Death Dis. 2018. PMID: 30478302 Free PMC article.
γ-Secretase inhibitor I induces apoptosis in chronic lymphocytic leukemia cells by proteasome inhibition, endoplasmic reticulum stress increase and notch down-regulation.
Rosati E, Sabatini R, De Falco F, Del Papa B, Falzetti F, Di Ianni M, Cavalli L, Fettucciari K, Bartoli A, Screpanti I, Marconi P. Rosati E, et al. Among authors: sabatini r. Int J Cancer. 2013 Apr 15;132(8):1940-53. doi: 10.1002/ijc.27863. Epub 2012 Oct 17. Int J Cancer. 2013. PMID: 23001755 Free article.
Novel targets for endoplasmic reticulum stress-induced apoptosis in B-CLL.
Rosati E, Sabatini R, Rampino G, De Falco F, Di Ianni M, Falzetti F, Fettucciari K, Bartoli A, Screpanti I, Marconi P. Rosati E, et al. Among authors: sabatini r. Blood. 2010 Oct 14;116(15):2713-23. doi: 10.1182/blood-2010-03-275628. Epub 2010 Jul 13. Blood. 2010. PMID: 20628148 Free article.