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A transgenic minipig model of Huntington's disease shows early signs of behavioral and molecular pathologies.
Askeland G, Rodinova M, Štufková H, Dosoudilova Z, Baxa M, Smatlikova P, Bohuslavova B, Klempir J, Nguyen TD, Kuśnierczyk A, Bjørås M, Klungland A, Hansikova H, Ellederova Z, Eide L. Askeland G, et al. Among authors: rodinova m. Dis Model Mech. 2018 Oct 24;11(10):dmm035949. doi: 10.1242/dmm.035949. Dis Model Mech. 2018. PMID: 30254085 Free PMC article.
Deterioration of mitochondrial bioenergetics and ultrastructure impairment in skeletal muscle of a transgenic minipig model in the early stages of Huntington's disease.
Rodinova M, Krizova J, Stufkova H, Bohuslavova B, Askeland G, Dosoudilova Z, Juhas S, Juhasova J, Ellederova Z, Zeman J, Eide L, Motlik J, Hansikova H. Rodinova M, et al. Dis Model Mech. 2019 Jul 26;12(7):dmm038737. doi: 10.1242/dmm.038737. Dis Model Mech. 2019. PMID: 31278192 Free PMC article.
Mitochondrial Metabolism in a Large-Animal Model of Huntington Disease: The Hunt for Biomarkers in the Spermatozoa of Presymptomatic Minipigs.
Krizova J, Stufkova H, Rodinova M, Macakova M, Bohuslavova B, Vidinska D, Klima J, Ellederova Z, Pavlok A, Howland DS, Zeman J, Motlik J, Hansikova H. Krizova J, et al. Among authors: rodinova m. Neurodegener Dis. 2017;17(4-5):213-226. doi: 10.1159/000475467. Epub 2017 Jun 21. Neurodegener Dis. 2017. PMID: 28633139