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An HLA-A*11:01-Binding Neoantigen from Mutated NPM1 as Target for TCR Gene Therapy in AML.
van der Lee DI, Koutsoumpli G, Reijmers RM, Honders MW, de Jong RCM, Remst DFG, Wachsmann TLA, Hagedoorn RS, Franken KLMC, Kester MGD, Harber KJ, Roelofsen LM, Schouten AM, Mulder A, Drijfhout JW, Veelken H, van Veelen PA, Heemskerk MHM, Falkenburg JHF, Griffioen M. van der Lee DI, et al. Among authors: roelofsen lm. Cancers (Basel). 2021 Oct 27;13(21):5390. doi: 10.3390/cancers13215390. Cancers (Basel). 2021. PMID: 34771556 Free PMC article.
An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer.
Voabil P, de Bruijn M, Roelofsen LM, Hendriks SH, Brokamp S, van den Braber M, Broeks A, Sanders J, Herzig P, Zippelius A, Blank CU, Hartemink KJ, Monkhorst K, Haanen JBAG, Schumacher TN, Thommen DS. Voabil P, et al. Among authors: roelofsen lm. Nat Med. 2021 Jul;27(7):1250-1261. doi: 10.1038/s41591-021-01398-3. Epub 2021 Jul 8. Nat Med. 2021. PMID: 34239134
Anti-Inflammatory Drugs Remodel the Tumor Immune Environment to Enhance Immune Checkpoint Blockade Efficacy.
Pelly VS, Moeini A, Roelofsen LM, Bonavita E, Bell CR, Hutton C, Blanco-Gomez A, Banyard A, Bromley CP, Flanagan E, Chiang SC, Jørgensen C, Schumacher TN, Thommen DS, Zelenay S. Pelly VS, et al. Among authors: roelofsen lm. Cancer Discov. 2021 Oct;11(10):2602-2619. doi: 10.1158/2159-8290.CD-20-1815. Epub 2021 May 24. Cancer Discov. 2021. PMID: 34031121 Free PMC article.