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Page 1
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases.
Cuadrado A, Rojo AI, Wells G, Hayes JD, Cousin SP, Rumsey WL, Attucks OC, Franklin S, Levonen AL, Kensler TW, Dinkova-Kostova AT. Cuadrado A, et al. Among authors: rojo ai. Nat Rev Drug Discov. 2019 Apr;18(4):295-317. doi: 10.1038/s41573-018-0008-x. Nat Rev Drug Discov. 2019. PMID: 30610225 Review.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R… See abstract for full author list ➔ Klionsky DJ, et al. Among authors: rojo ai. Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8. Autophagy. 2021. PMID: 33634751 Free PMC article.
On the Clinical Pharmacology of Reactive Oxygen Species.
Casas AI, Nogales C, Mucke HAM, Petraina A, Cuadrado A, Rojo AI, Ghezzi P, Jaquet V, Augsburger F, Dufrasne F, Soubhye J, Deshwal S, Di Sante M, Kaludercic N, Di Lisa F, Schmidt HHHW. Casas AI, et al. Among authors: rojo ai. Pharmacol Rev. 2020 Oct;72(4):801-828. doi: 10.1124/pr.120.019422. Pharmacol Rev. 2020. PMID: 32859763 Free article. Review.
Specific targeting of the NRF2/β-TrCP axis promotes beneficial effects in NASH.
Fernández-Ginés R, Encinar JA, Escoll M, Carnicero-Senabre D, Jiménez-Villegas J, García-Yagüe ÁJ, González-Rodríguez Á, Garcia-Martinez I, Valverde ÁM, Rojo AI, Cuadrado A. Fernández-Ginés R, et al. Among authors: rojo ai. Redox Biol. 2024 Feb;69:103027. doi: 10.1016/j.redox.2024.103027. Epub 2024 Jan 3. Redox Biol. 2024. PMID: 38184999 Free PMC article.
Overlooked and valuable facts to know in the NRF2/KEAP1 field.
Kopacz A, Rojo AI, Patibandla C, Lastra-Martínez D, Piechota-Polanczyk A, Kloska D, Jozkowicz A, Sutherland C, Cuadrado A, Grochot-Przeczek A. Kopacz A, et al. Among authors: rojo ai. Free Radic Biol Med. 2022 Nov 1;192:37-49. doi: 10.1016/j.freeradbiomed.2022.08.044. Epub 2022 Sep 12. Free Radic Biol Med. 2022. PMID: 36100148 Free article. Review. No abstract available.
Can Activation of NRF2 Be a Strategy against COVID-19?
Cuadrado A, Pajares M, Benito C, Jiménez-Villegas J, Escoll M, Fernández-Ginés R, Garcia Yagüe AJ, Lastra D, Manda G, Rojo AI, Dinkova-Kostova AT. Cuadrado A, et al. Among authors: rojo ai. Trends Pharmacol Sci. 2020 Sep;41(9):598-610. doi: 10.1016/j.tips.2020.07.003. Epub 2020 Jul 14. Trends Pharmacol Sci. 2020. PMID: 32711925 Free PMC article. Review.
NRF2 as a therapeutic opportunity to impact in the molecular roadmap of ALS.
Jiménez-Villegas J, Ferraiuolo L, Mead RJ, Shaw PJ, Cuadrado A, Rojo AI. Jiménez-Villegas J, et al. Among authors: rojo ai. Free Radic Biol Med. 2021 Sep;173:125-141. doi: 10.1016/j.freeradbiomed.2021.07.022. Epub 2021 Jul 24. Free Radic Biol Med. 2021. PMID: 34314817 Free article. Review.
52 results