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Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes.

Kent OA, Saha M, Coyaud E, Burston HE, Law N, Dadson K, Chen S, Laurent EM, St-Germain J, Sun RX, Matsumoto Y, Cowen J, Montgomery-Song A, Brown KR, Ishak C, Rose J, De Carvalho DD, He HH, Raught B, Billia F, Kannu P, Rottapel R. Kent OA, et al. Among authors: rottapel r. Nat Commun. 2020 Sep 16;11(1):4673. doi: 10.1038/s41467-020-18483-9. Nat Commun. 2020. PMID: 32938917 Free PMC article.

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Bone dynamics and inflammation: lessons from rare diseases.

Matsumoto Y, Rottapel R. Matsumoto Y, et al. Among authors: rottapel r. Immunol Med. 2020 Jun;43(2):61-64. doi: 10.1080/25785826.2020.1720104. Epub 2020 Jan 30. Immunol Med. 2020. PMID: 31999934 Review.

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The LUBAC participates in lysophosphatidic acid-induced NF-κB activation.

Douanne T, Chapelier S, Rottapel R, Gavard J, Bidère N. Douanne T, et al. Among authors: rottapel r. Cell Immunol. 2020 Jul;353:104133. doi: 10.1016/j.cellimm.2020.104133. Epub 2020 May 18. Cell Immunol. 2020. PMID: 32450431

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Rheumatic immune-related adverse events associated with cancer immunotherapy: A nationwide multi-center cohort.

Roberts J, Ennis D, Hudson M, Ye C, Saltman A, Himmel M, Rottapel R, Pope J, Hoa S, Tisseverasinghe A, Fifi-Mah A, Maltez N, Jamal S. Roberts J, et al. Among authors: rottapel r. Autoimmun Rev. 2020 Aug;19(8):102595. doi: 10.1016/j.autrev.2020.102595. Epub 2020 Jun 11. Autoimmun Rev. 2020. PMID: 32535092 Review.

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Go with the flow: GEF-H1 mediated shear stress mechanotransduction in neutrophils.

Fine N, Dimitriou ID, Rottapel R. Fine N, et al. Among authors: rottapel r. Small GTPases. 2020 Jan;11(1):23-31. doi: 10.1080/21541248.2017.1332505. Epub 2017 Nov 30. Small GTPases. 2020. PMID: 29188751 Free PMC article. Review.

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Nucleotide Binding, Evolutionary Insights, and Interaction Partners of the Pseudokinase Unc-51-like Kinase 4.

Preuss F, Chatterjee D, Mathea S, Shrestha S, St-Germain J, Saha M, Kannan N, Raught B, Rottapel R, Knapp S. Preuss F, et al. Among authors: rottapel r. Structure. 2020 Nov 3;28(11):1184-1196.e6. doi: 10.1016/j.str.2020.07.016. Epub 2020 Aug 18. Structure. 2020. PMID: 32814032

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GEF-H1 Is Required for Colchicine Inhibition of Neutrophil Rolling and Recruitment in Mouse Models of Gout.

Fine N, Gracey E, Dimitriou I, La Rose J, Glogauer M, Rottapel R. Fine N, et al. Among authors: rottapel r. J Immunol. 2020 Dec 15;205(12):3300-3310. doi: 10.4049/jimmunol.1900783. Epub 2020 Nov 16. J Immunol. 2020. PMID: 33199537

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The adapter 3BP2: how it plugs into leukocyte signaling.

Deckert M, Rottapel R. Deckert M, et al. Among authors: rottapel r. Adv Exp Med Biol. 2006;584:107-14. doi: 10.1007/0-387-34132-3_8. Adv Exp Med Biol. 2006. PMID: 16802602 Review. No abstract available.

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Alveolar Bone Protection by Targeting the SH3BP2-SYK Axis in Osteoclasts.

Kittaka M, Yoshimoto T, Schlosser C, Rottapel R, Kajiya M, Kurihara H, Reichenberger EJ, Ueki Y. Kittaka M, et al. Among authors: rottapel r. J Bone Miner Res. 2020 Feb;35(2):382-395. doi: 10.1002/jbmr.3882. Epub 2019 Oct 24. J Bone Miner Res. 2020. PMID: 31613396 Free PMC article.

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Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways.

Azoitei ML, Noh J, Marston DJ, Roudot P, Marshall CB, Daugird TA, Lisanza SL, Sandí MJ, Ikura M, Sondek J, Rottapel R, Hahn KM, Danuser G. Azoitei ML, et al. Among authors: rottapel r. J Cell Biol. 2019 Sep 2;218(9):3077-3097. doi: 10.1083/jcb.201812073. Epub 2019 Aug 16. J Cell Biol. 2019. PMID: 31420453 Free PMC article.

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