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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
1985 1
1988 2
1994 1
1996 1
1997 1
1998 2
1999 5
2000 5
2001 9
2002 15
2003 13
2004 6
2005 14
2006 3
2007 10
2008 16
2009 9
2010 20
2011 22
2012 14
2013 22
2014 11
2015 11
2016 7
2017 9
2018 5
2019 6
2020 3
2021 4
2022 2
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223 results
Results by year
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Page 1
Targeting the NLRP3 inflammasome in inflammatory diseases.
Mangan MSJ, Olhava EJ, Roush WR, Seidel HM, Glick GD, Latz E. Mangan MSJ, et al. Among authors: roush wr. Nat Rev Drug Discov. 2018 Aug;17(8):588-606. doi: 10.1038/nrd.2018.97. Epub 2018 Jul 20. Nat Rev Drug Discov. 2018. PMID: 30026524 Review.
Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer.
Quereda V, Bayle S, Vena F, Frydman SM, Monastyrskyi A, Roush WR, Duckett DR. Quereda V, et al. Among authors: roush wr. Cancer Cell. 2019 Nov 11;36(5):545-558.e7. doi: 10.1016/j.ccell.2019.09.004. Epub 2019 Oct 24. Cancer Cell. 2019. PMID: 31668947 Free article.
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.
Renner K, Bruss C, Schnell A, Koehl G, Becker HM, Fante M, Menevse AN, Kauer N, Blazquez R, Hacker L, Decking SM, Bohn T, Faerber S, Evert K, Aigle L, Amslinger S, Landa M, Krijgsman O, Rozeman EA, Brummer C, Siska PJ, Singer K, Pektor S, Miederer M, Peter K, Gottfried E, Herr W, Marchiq I, Pouyssegur J, Roush WR, Ong S, Warren S, Pukrop T, Beckhove P, Lang SA, Bopp T, Blank CU, Cleveland JL, Oefner PJ, Dettmer K, Selby M, Kreutz M. Renner K, et al. Among authors: roush wr. Cell Rep. 2019 Oct 1;29(1):135-150.e9. doi: 10.1016/j.celrep.2019.08.068. Cell Rep. 2019. PMID: 31577944 Free article.
Structure Based Design of CYP51 Inhibitors.
Choi JY, Roush WR. Choi JY, et al. Among authors: roush wr. Curr Top Med Chem. 2017;17(1):30-39. doi: 10.2174/1568026616666160719164933. Curr Top Med Chem. 2017. PMID: 27449014 Review.
Acute urinary retention.
Fontanarosa PB, Roush WR. Fontanarosa PB, et al. Among authors: roush wr. Emerg Med Clin North Am. 1988 Aug;6(3):419-37. Emerg Med Clin North Am. 1988. PMID: 3292220 Review.
The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis.
Torres S, Brol MJ, Magdaleno F, Schierwagen R, Uschner FE, Klein S, Ortiz C, Tyc O, Bachtler N, Stunden J, Bertheloot D, Kitanovic A, Sanchez B, Schrum J, Roush WR, Franchi L, Byth K, Latz E, Trebicka J. Torres S, et al. Among authors: roush wr. Front Mol Biosci. 2021 Aug 13;8:715765. doi: 10.3389/fmolb.2021.715765. eCollection 2021. Front Mol Biosci. 2021. PMID: 34513923 Free PMC article.
ML302, a Novel Beta-lactamase (BLA) Inhibitor.
Spicer T, Minond D, Enogieru I, Saldanha SA, Allais C, Liu Q, Mercer BA, Roush WR, Hodder P. Spicer T, et al. Among authors: roush wr. 2012 Apr 16 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Apr 16 [updated 2014 May 13]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23762954 Free Books & Documents. Review.
Drug strategies targeting CYP51 in neglected tropical diseases.
Choi JY, Podust LM, Roush WR. Choi JY, et al. Among authors: roush wr. Chem Rev. 2014 Nov 26;114(22):11242-71. doi: 10.1021/cr5003134. Epub 2014 Oct 22. Chem Rev. 2014. PMID: 25337991 Free PMC article. Review. No abstract available.
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.
Schreiber SL, Kotz JD, Li M, Aubé J, Austin CP, Reed JC, Rosen H, White EL, Sklar LA, Lindsley CW, Alexander BR, Bittker JA, Clemons PA, de Souza A, Foley MA, Palmer M, Shamji AF, Wawer MJ, McManus O, Wu M, Zou B, Yu H, Golden JE, Schoenen FJ, Simeonov A, Jadhav A, Jackson MR, Pinkerton AB, Chung TD, Griffin PR, Cravatt BF, Hodder PS, Roush WR, Roberts E, Chung DH, Jonsson CB, Noah JW, Severson WE, Ananthan S, Edwards B, Oprea TI, Conn PJ, Hopkins CR, Wood MR, Stauffer SR, Emmitte KA; NIH Molecular Libraries Project Team. Schreiber SL, et al. Among authors: roush wr. Cell. 2015 Jun 4;161(6):1252-65. doi: 10.1016/j.cell.2015.05.023. Cell. 2015. PMID: 26046436 Free PMC article. Review.
223 results